Propionibacterium acnes causing non-contiguous, multifocal spondylodiscitis in an immunosuppressed patient

Propionibacterium acnes causing non-contiguous, multifocal spondylodiscitis in an immunosuppressed patient

This report describes a case of a spondylodiscitis in an immunocompromised patient with an HIV infection caused by Propionibacterium acnes . The patient was admitted to hospital with a sudden loss of motor function and sensation in both of the patient’s legs. A biopsy taken during the first debridem...

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Bibliographic Details
Published in:BMJ case reports Vol. 14; no. 9; p. e242420
Main Authors: Ozolina, Elina, Auslands, Kaspars, Buks, Maris, Ansons, Martins
Format: Journal Article
Language:English
Published: London BMJ Publishing Group LTD 20-09-2021
BMJ Publishing Group
Subjects:
Antibiotics
Back pain
Biopsy
Case Report
Case reports
Debridement
Drug use
Edema
Epidural
Genetic testing
Hemoglobin
HIV
Human immunodeficiency virus
Infections
Muscle strength
Patients
Physical therapy
Skin
Spinal cord
Substance abuse treatment
Surgery
Trauma
Tuberculosis
Vertebrae
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Summary:This report describes a case of a spondylodiscitis in an immunocompromised patient with an HIV infection caused by Propionibacterium acnes . The patient was admitted to hospital with a sudden loss of motor function and sensation in both of the patient’s legs. A biopsy taken during the first debridement operation proved to be negative for Mycobacterium tuberculosis DNA and growth, but was positive for the growth of P. acnes . Following a course of antibiotic therapy and the aforementioned debridement, the patient was moved to a specialised clinic for physical therapy. The patient’s condition quickly deteriorated, and the patient once again required extensive debridement. Repeated spinal surgery, antibiotics for 12 weeks and subsequent rehabilitation resulted in almost complete recovery of sensorimotor limb function.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2021-242420