Search Results - "Anson, R Michael"

Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories by Mitchell, Sarah J., Bernier, Michel, Mattison, Julie A., Aon, Miguel A., Kaiser, Tamzin A., Anson, R. Michael, Ikeno, Yuji, Anderson, Rozalyn M., Ingram, Donald K., de Cabo, Rafael

“…The importance of dietary composition and feeding patterns in aging remains largely unexplored, but was implicated recently in two prominent nonhuman primate…”
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Caloric Restriction Study Design Limitations in Rodent and Nonhuman Primate Studies by Vaughan, Kelli L, Kaiser, Tamzin, Peaden, Robert, Anson, R Michael, de Cabo, Rafael, Mattison, Julie A

“…Abstract For a century, we have known that caloric restriction influences aging in many species. However, only recently it was firmly established that the…”
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Intermittent Fasting Dissociates Beneficial Effects of Dietary Restriction on Glucose Metabolism and Neuronal Resistance to Injury from Calorie Intake by Anson, R. Michael, Guo, Zhihong, de Cabo, Rafael, Iyun, Titilola, Rios, Michelle, Hagepanos, Adrienne, Ingram, Donald K., Lane, Mark A., Mattson, Mark P.

“…Dietary restriction has been shown to have several health benefits including increased insulin sensitivity, stress resistance, reduced morbidity, and increased…”
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Development of Calorie Restriction Mimetics as a Prolongevity Strategy by INGRAM, DONALD K., ANSON, R MICHAEL, DE CABO, RAFAEL, MAMCZARZ, JACEK, ZHU, MIN, MATTISON, JULIE, LANE, MARK A., ROTH, GEORGE S.

“…: By applying calorie restriction (CR) at 30‐50% below ad libitum levels, studies in numerous species have reported increased life span, reduced incidence and…”
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The Importance of Networks by Anson, R Michael

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Within- and between-species study of extreme longevity--comments, commonalities, and goals by Anson, R Michael, Willcox, Bradley, Austad, Steven, Perls, Thomas

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The diet restriction paradigm: a brief review of the effects of every-other-day feeding by Anson, R Michael, Jones, Bruce, de Cabod, Rafael

“…It has been known since the early 1900s that restriction of dietary intake relative to the ad libitum (AL) level increases stress resistance, cancer…”
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An in vitro model of caloric restriction by de Cabo, Rafael, Fürer-Galbán, Stefanie, Anson, R.Michael, Gilman, Charles, Gorospe, Myriam, Lane, Mark A.

“…The mechanisms underlying the ability of caloric restriction (CR) to extend life span and enhance stress responsiveness remain elusive. Progress in this area…”
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Mitochondrial endogenous oxidative damage has been overestimated by Michael Anson, R., Hudson, Edgar, Bohr, Vilhelm A.

“…ABSTRACT The oxidatively induced DNA lesion 8‐oxo‐dG in mitochondrial DNA (mtDNA) is commonly used as a marker for oxidative damage to mitochondria, which in…”
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Absolute versus Relative Caloric Intake: Clues to the Mechanism of Calorie/Aging-Rate Interactions by ANSON, R MICHAEL

“…: It has been suggested that the influence of caloric intake on aging rate is not due to the absolute number of calories ingested. Instead, aging rate is…”
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Mitochondrial influence on aging rate in Caenorhabditis elegans by Anson, R. Michael, Hansford, Richard G.

“…Summary Virtually every model of mitochondrial involvement in aging shares the underlying proposition that mitochondrial dysfunction will accelerate the rate…”
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Gene-specific and mitochondrial repair of oxidative DNA damage by Anson, R Michael, Mason, Penelope A, Bohr, Vilhelm A

“…The Southern blot gene-specific DNA damage and repair assay is a robust and flexible method for quantifying many kinds of induced damage and repair with high…”
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Caloric restriction modulates insulin receptor signaling in liver and skeletal muscle of rat by Zhu, Min, de Cabo, Rafael, Anson, R. Michael, Ingram, Donald K., Lane, Mark A.

“…We investigated how the insulin/insulin-like growth factor-1 signaling pathway is involved in the robust antiaging effects produced by caloric restriction. We…”
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Mitochondrial DNA repair pathways by Bohr, V A, Anson, R M

“…It has long been held that there is no DNA repair in mitochondria. Early observations suggested that the reason for the observed accumulation of DNA damage in…”
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Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA by Anson, R. Michael, Croteau, Deborah L., Stierum, Rob H., Filburn, Charles, Parsell, Robin, Bohr, Vilhelm A.

“…Photoactivated methylene blue was used to damage purified DNA and the mitochondrial DNA (mtDNA) of human fibroblasts in culture. The primary product of this…”
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Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice by Mitchell, Sarah J., Madrigal-Matute, Julio, Scheibye-Knudsen, Morten, Fang, Evandro, Aon, Miguel, González-Reyes, José A., Cortassa, Sonia, Kaushik, Susmita, Gonzalez-Freire, Marta, Patel, Bindi, Wahl, Devin, Ali, Ahmed, Calvo-Rubio, Miguel, Burón, María I., Guiterrez, Vincent, Ward, Theresa M., Palacios, Hector H., Cai, Huan, Frederick, David W., Hine, Christopher, Broeskamp, Filomena, Habering, Lukas, Dawson, John, Beasley, T. Mark, Wan, Junxiang, Ikeno, Yuji, Hubbard, Gene, Becker, Kevin G., Zhang, Yongqing, Bohr, Vilhelm A., Longo, Dan L., Navas, Placido, Ferrucci, Luigi, Sinclair, David A., Cohen, Pinchas, Egan, Josephine M., Mitchell, James R., Baur, Joseph A., Allison, David B., Anson, R. Michael, Villalba, José M., Madeo, Frank, Cuervo, Ana Maria, Pearson, Kevin J., Ingram, Donald K., Bernier, Michel, de Cabo, Rafael

“…Calorie restriction (CR) is the most robust non-genetic intervention to delay aging. However, there are a number of emerging experimental variables that alter…”
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Mitochondria, oxidative DNA damage, and aging by Anson, R M, Bohr, V A

“…Protection from reactive oxygen species (ROS) and from mitochondrial oxidative damage is well known to be necessary to longevity. The relevance of…”
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The arcuate nucleus and NPY contribute to the antitumorigenic effect of calorie restriction by Minor, Robin K., López, Miguel, Younts, Caitlin M., Jones, Bruce, Pearson, Kevin J., Anson, R. Michael, Diéguez, Carlos, de Cabo, Rafael

“…Calorie restriction (CR) is known to have profound effects on tumor incidence. A typical consequence of CR is hunger, and we hypothesized that the…”
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Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal restistance to injury to calorie intake by Anson, R Michael, Guo, Zhihong, de Cabo, Rafael, Iyun, Titilola

“…Dietary restriction has been shown to have several health benefits including increased insulin sensitivity, stress resistance, reduced morbidity, and increased…”
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CALORIES, FREE RADICALS, AND GENE HOMOLOGY: EXAMINING THE SACRED COWS OF TODAY'S BIOGERONTOLOGICAL RESEARCH by Anson, R Michael, Handy, April

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