Search Results - "Anshika Bajaj"
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Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic Stroke
Published in Cell reports (Cambridge) (11-09-2018)“…Cerebrovascular malformations (CVMs) affect approximately 3% of the population, risking hemorrhagic stroke, seizures, and neurological deficits. Recently Ras…”
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Loss of NF1 expression in human endothelial cells promotes autonomous proliferation and altered vascular morphogenesis
Published in PloS one (07-11-2012)“…Neurofibromatosis is a well known familial tumor syndrome, however these patients also suffer from a number of vascular anomalies. The loss of NFl from the…”
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Activation of Endothelial Ras Signaling Bypasses Senescence and Causes Abnormal Vascular Morphogenesis
Published in Cancer research (Chicago, Ill.) (01-05-2010)“…Angiogenesis is crucial for embryogenesis, reproduction, and wound healing and is a critical determinant of tumor growth and metastasis. The multifunctional…”
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Abstract 5092: ZVex® lentiviral vector strongly activates pro-inflammatory, antigen processing, and anti-viral defense response pathways in monocyte-derived dendritic cells
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Background: Dendritic cells (DCs) are professional antigen presenting cells that effectively bridge the innate and adaptive immune responses and require…”
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Abstract 5919: Component-specific qPCR assays for characterization and identity testing of multigenome ZVex®, a dendritic cell-targeting lentiviral vector platform
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Background: ZVex is a novel, integration-deficient, dendritic cell-targeting lentiviral vector platform currently being evaluated in clinical trials in sarcoma…”
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Oligomerization of the Yeast α-Factor Receptor: IMPLICATIONS FOR DOMINANT NEGATIVE EFFECTS OF MUTANT RECEPTORS
Published in The Journal of biological chemistry (28-07-2006)“…Oligomerization of G protein-coupled receptors is commonly observed, but the functional significance of oligomerization for this diverse family of receptors…”
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Abstract 4884: Intratumoral expression of IL-12 from a dendritic cell-targeting chimeric lentiviral vector from the ZVex platform cures established tumors in multiple models and induces systemic anti-tumor responses
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Interleukin-12 (IL-12), produced by antigen-presenting cells, plays a pivotal role in the interplay between innate and adaptive arms of the immune system…”
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Identification of the Protein Target of Myelin-Binding Ligands by Immunohistochemistry and Biochemical Analyses
Published in The journal of histochemistry and cytochemistry (01-01-2013)“…The ability to visualize myelin is important in the diagnosis of demyelinating disorders and the detection of myelin-containing nerves during surgery. The…”
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Intraoperative Fluorescence Imaging of Peripheral and Central Nerves Through a Myelin-Selective Contrast Agent
Published in Molecular imaging and biology (01-12-2012)“…Purpose Patients suffer from complications as a result of unintentional nerve damage during surgery. We focus on improving intraoperative visualization of…”
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Differential Interactions of Fluorescent Agonists and Antagonists with the Yeast G Protein Coupled Receptor Ste2p
Published in Journal of molecular biology (17-06-2011)“…We describe a rapid method to probe for mutations in cell surface ligand-binding proteins that affect the environment of bound ligand. The method uses…”
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Fluorescence phenomena in nerve-labeling styryl-type dyes
Published in Journal of photochemistry and photobiology. A, Chemistry. (01-02-2016)“…[Display omitted] •Synthesized and investigated photophysical properties of several substituted styryl type dyes d1–d15.•Three dyes d7, d9 and d10 showed good…”
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Dual-mode laparoscopic fluorescence image-guided surgery using a single camera
Published in Biomedical optics express (01-08-2012)“…Iatrogenic nerve damage is a leading cause of morbidity associated with many common surgical procedures. Complications arising from these injuries may result…”
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Oligomerization of the Yeast α-Factor Receptor
Published in The Journal of biological chemistry (28-07-2006)“…Oligomerization of G protein-coupled receptors is commonly observed, but the functional significance of oligomerization for this diverse family of receptors…”
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Journal Article -
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Oligomerization of the Yeast α-Factor Receptor
Published in The Journal of biological chemistry (28-07-2006)“…Oligomerization of G protein-coupled receptors is commonly observed, but the functional significance of oligomerization for this diverse family of receptors…”
Get full text
Journal Article -
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Role of extracellular charged amino acids in the yeast α-factor receptor
Published in Biochimica et biophysica acta (01-06-2007)“…The yeast pheromone receptor, Ste2p, is a G protein coupled receptor that initiates cellular responses to α-mating pheromone, a 13 residue peptide that carries…”
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Journal Article -
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A Fluorescent α-Factor Analogue Exhibits Multiple Steps on Binding to Its G Protein Coupled Receptor in Yeast
Published in Biochemistry (Easton) (26-10-2004)“…The yeast α-factor receptor encoded by the STE2 gene is a member of the extended family of G protein coupled receptors (GPCRs) involved in a wide variety of…”
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Ligand binding and receptor activation in a G protein coupled receptor in baker's yeast Saccharomyces cerevisiae
Published 01-01-2006“…The STE2 receptor in yeast belongs to the extended family of G protein coupled receptors (GPCRs) that are involved in multiple signal transduction pathways…”
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Dissertation -
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Fluorescence image guided surgical instruments and contrast agents for intraoperative visualization of nerves
Published in 2012 Conference on Lasers and Electro-Optics (CLEO) (01-05-2012)“…Fluorescence image-guided surgery (FIGS) improves intraoperative visualization of critical structures. We describe the advancement of handheld and minimally…”
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Conference Proceeding