Search Results - "Anselme, Ann C."

Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXs by Reddy, Tejaswini P, Choi, Dong S, Anselme, Ann C, Qian, Wei, Chen, Wen, Lantto, Johan, Horak, Ivan D, Kragh, Michael, Chang, Jenny C, Rosato, Roberto R

“…The human epidermal growth factor receptor (HER) family, notably EGFR, is overexpressed in most triple-negative breast cancer (TNBC) cases and provides cancer…”
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Tocilizumab overcomes chemotherapy resistance in mesenchymal stem-like breast cancer by negating autocrine IL-1A induction of IL-6 by Chung, Andrew W., Kozielski, Anthony J., Qian, Wei, Zhou, Jianying, Anselme, Ann C., Chan, Alfred A., Pan, Ping-Ying, Lee, Delphine J., Chang, Jenny C.

“…Triple-negative breast cancer (TNBC) patients with mesenchymal stem-like (MSL) subtype have responded poorly to chemotherapy whereas patients with basal-like 1…”
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A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer by Chung, Andrew W, Anand, Kartik, Anselme, Ann C, Chan, Alfred A, Gupta, Nakul, Venta, Luz A, Schwartz, Mary R, Qian, Wei, Xu, Yitian, Zhang, Licheng, Kuhn, John, Patel, Tejal, Rodriguez, Angel A, Belcheva, Anna, Darcourt, Jorge, Ensor, Joe, Bernicker, Eric, Pan, Ping-Ying, Chen, Shu Hsia, Lee, Delphine J, Niravath, Polly A, Chang, Jenny C

“…The inducible nitric oxide signaling (iNOS) pathway is associated with poor prognosis in triple-negative breast cancer (TNBC). Prior studies using in vivo…”
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Abstract P5-17-07: Phase 1B/2 clinical trial targeting nitric oxide in the treatment of chemo-refractory metaplastic triple-negative breast cancer patients by Puri, Akshjot, Ordonez, Adriana, Anselme, Ann C., Guzman, Liliana, Niravath, Polly, Chang, Jenny C.

“…Abstract BACKGROUND Metaplastic breast cancer (MpBC) is an extremely rare, therapeutically recalcitrant and aggressive variant of triple negative breast cancer…”
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Abstract 2261: Understanding the mechanism underlying resistance to immunotherapy in TNBC by Anselme, Ann C., Qian, Wei, Kozielski, Anthony, Rosato, Roberto R., Chang, Jenny C.

“…Abstract Triple Negative Breast Cancer (TNBC) accounts for 15-20% of all breast cancer cases. TNBC patients have the worst outcome amongst all breast cancers;…”
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Abstract P3-07-09: Pan-NOS Inhibitor L-NMMA in combination with Docetaxel Enhances Antitumor Effect in Obesity-associated Triple Negative Breast Cancer by Sun, Kai, anselme, Ann C., Qian, Wei, Zhou, Jianying, Cheng, Robert, Rosato, Roberto, Chang, Jenny

“…Abstract Background: Obesity is associated with increased risk of triple negative breast cancer (TNBC). Obese patients with TNBC have worse outcomes compared…”
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