Search Results - "Ansell, J. D."

Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures by Clutton, S.M., Townsend, K.M.S., Walker, C., Ansell, J.D., Wright, E.G.

“…There is accumulating evidence that cells exposed to low and often environmentally relevant doses of ionizing radiation survive the initial insult, but…”
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A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro by HOLE, N, GRAHAM, G. J, MENZEL, U, ANSELL, J. D

“…Embryonal stem cells have been shown to differentiate in vitro into all hematopoietic lineages. This has been used successfully as one approach to the study of…”
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DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability by Bentley, Darren J, Selfridge, Jim, Millar, J. Kirsty, Samuel, Kay, Hole, Nicholas, Ansell, John D, Melton, David W

“…Four distinct DNA ligase activities (I-IV) have been identified within mammalian cells. Evidence has indicated that DNA ligase I is central to DNA replication,…”
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The use of a multiple criteria decision analysis to evaluate the effectiveness of landscape and habitat enhancement mechanisms: An example from the South Downs by Park, J. R., Stabler, M. J., Mortimer, S. R., Jones, P. J., Ansell, D. J., Parker, G. P. D.

“…A range of funding schemes and policy instruments exist to effect enhancement of the landscapes and habitats of the UK. While a number of assessments of these…”
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Uptake and distribution of N-acetylcysteine in mice: tissue-specific effects on glutathione concentrations by McLellan, L I, Lewis, A D, Hall, D J, Ansell, J D, Wolf, C R

“…Modulation of cellular thiols has been used to ameliorate the toxic side effects associated with cancer chemotherapy and is currently being investigated as a…”
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C-Terminal Truncation of WT1 Delays but Does Not Abolish Hematopoiesis in Embryoid Bodies by Wagner, K.J., Patek, C.E., Cunningham, A., Taylor, A.H., Hooper, M.L., Ansell, J.D.

“…ABSTRACT The effect of mutations that truncate the WT1 protein on in vitro hematopoietic differentiation from embryonal stem cells has been examined by CFU-A…”
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Numbers and dispersion of repopulating hematopoietic cell clones in radiation chimeras as functions of injected cell dose by Micklem, H S, Lennon, J E, Ansell, J D, Gray, R A

“…Lethally irradiated mice were repopulated with low (10(5)), medium (10(6)) or high (10(7)) doses of congenic bone marrow cells. Marrow donors were heterozygous…”
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Special Proliferative Sites are not Needed for Seeding and Proliferation of Transfused Bone Marrow Cells in Normal Syngeneic Mice by Brecher, G., Ansell, J. D., Micklem, H. S., J.-H. Tjio, Cronkite, E. P.

“…The widely held view that transfused bone marrow cells will not proliferate in normal mice, not exposed to irradiation or other forms of bone marrow ablation,…”
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Age-dependent selection against hypoxanthine phosphoribosyl transferase-deficient cells in mouse haematopoiesis by SAMUEL, K, CLARKE, A. R, ANSELL, J. D, HOOPER, M. L

“…The basis of a previously observed difference in the level of contribution of hypoxanthine phosphoribosyltransferase-deficient cells between the haematopoietic…”
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Development of B lymphocytes in mice heterozygous for the X-linked immunodeficiency (xid) mutation: xid inhibits development of all splenic and lymph node B cells at a stage subsequent to their initial formation in bone marrow by FORRESTER, L. M, ANSELL, J. D, MICKLEM, H. S

“…CBA/N mice were crossed with CBA/Ca-Pgk-1a to produce female F1 hybrids that were heterozygous for both xid and the phosphoglycerate kinase 1 (PGK-1)…”
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The number of clonal precursors of the follicular epithelium in the mouse ovary by Telfer, E, Ansell, J D, Taylor, H, Gosden, R G

“…The number of clonal precursors of granulosa cells in mouse ovarian follicles has been estimated using a technique based on the phenomenon of random…”
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Polycystic kidney disease in the CBA/N immunodeficient mouse by Rahilly, M A, Samuel, K, Ansell, J D, Micklem, H S, Fleming, S

“…We describe a polycystic lesion of the kidney in the CBA/N mouse with an X-linked recessive immunodeficient syndrome. There is progressive cystic dilatation…”
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Cloning and Characterization of Ehox, a Novel Homeobox Gene Essential for Embryonic Stem Cell Differentiation by Jackson, Melany, Baird, Janet W., Cambray, Noemi, Ansell, John D., Forrester, Lesley M., Graham, Gerard J.

“…We report here the identification and characterization of a novel paired-like homeobox-containing gene (Ehox). This gene, identified in embryonic stem (ES)…”
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Hypoxanthine phosphoribosyl transferase deficiency, haematopoiesis and fertility in the mouse by ANSELL, J. D, SAMUEL, K, WHITTINGHAM, D. G, PATEK, C. E, HARDY, K, HANDYSIDE, A. H, JONES, K. W, MUGGLETON-HARRIS, A. L, TAYLOR, A. H, HOOPER, M. L

“…We have looked for effects of deficiency in hypoxanthine phosphoribosyl transferase (HPRT) in the mouse comparable to non-behavioural consequences of…”
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Clonal interaction in tumours by Woodruff, M. F. A, Ansell, J. D, Forbes, G. M, Gordon, J. C, Burton, D. I, Micklem, H. S

“…The development of cancer is contingent on the emergence of at least one clone of transformed cells. One method used to investigate whether human tumours are…”
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Evidence that decidual cells are not derived from bone marrow by Fowlis, D J, Ansell, J D

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The role of glutathione in determining the response of normal and tumor cells to anticancer drugs by Wolf, C R, Lewis, A D, Carmichael, J, Adams, D J, Allan, S G, Ansell, D J

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Establishment of Theileria-infected bovine cell lines in scid mice by Fell, A H, Preston, P M, Ansell, J D

“…Bovine cells transformed by infection with the protozoan parasite Theileria annulata were inoculated subcutaneously or intraperitoneally into C.B.-17 scid…”
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Oligoclonal tumours by Woodruff, M F, Ansell, J D, Hodson, B A, Potts, R B

“…Tumours are commonly classified as monoclonal or polyclonal. The question of how many clones are present in a polyclonal tumour is seldom asked; it is…”
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The provenance of cells in sarcomas induced in chimaeric mice by ANSELL, J. D, HODSON, B. A, WOODRUFF, M. F. A

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