Search Results - "Ansari , Naseem"

4-Hydroxynonenal in the pathogenesis and progression of human diseases by Shoeb, Mohammad, Ansari, Naseem H, Srivastava, Satish K, Ramana, Kota V

“…Metastable aldehydes produced by lipid peroxidation act as 'toxic second messengers' that extend the injurious potential of free radicals. 4-hydroxy 2-nonenal…”
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Metal chelation attenuates oxidative stress, inflammation, and vertical burn progression in a porcine brass comb burn model by El Ayadi, Amina, Salsbury, John R., Enkhbaatar, Perenlei, Herndon, David N., Ansari, Naseem H.

“…Oxidative stress and inflammation may mediate cellular damage and tissue destruction as the burn wound continues to progress after the abatement of the initial…”
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Thermal injury induces early blood vessel occlusion in a porcine model of brass comb burn by Wang, Jing, Wang, Cheng Z., Salsbury, John R., Zhang, Jianzi, Enkhbaatar, Perenlei, Herndon, David N., El Ayadi, Amina, Ansari, Naseem H.

“…Burn wound progression is an important determinant of patient morbidity and mortality after injury. In this study, we used the brass comb contact burn to…”
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Antidiabetic drug metformin suppresses endotoxin-induced uveitis in rats by Kalariya, Nilesh M, Shoeb, Mohammad, Ansari, Naseem H, Srivastava, Satish K, Ramana, Kota V

“…To investigate the therapeutic effects of metformin, a commonly used antidiabetic drug, in preventing endotoxin-induced uveitis (EIU) in rats. EIU in Lewis…”
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Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders by Srivastava, Satish K., Yadav, Umesh C.S., Reddy, Aramati B.M., Saxena, Ashish, Tammali, Ravinder, Shoeb, Mohammad, Ansari, Naseem H., Bhatnagar, Aruni, Petrash, Mark J., Srivastava, Sanjay, Ramana, Kota V.

“…Oxidative stress-induced inflammation is a major contributor to several disease conditions including sepsis, carcinogenesis and metastasis, diabetic…”
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Amelioration of Endotoxin-Induced Inflammatory Toxic Response by a Metal Chelator in Rat Eyes by Shoeb, Mohammad, Zhang, Min, Xiao, Tianlin, Syed, Misha F, Ansari, Naseem H

“…Metal ions play a key role in exacerbating toxicity associated with oxidative stress and inflammation. This study examines the effects of a formulation…”
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Aneurysm in a Large Sporadic Renal Angiomyolipoma by Al Omran , Bedoor, Ansari , Naseem

“…Angiomyolipomas (AMLs) are the most common mesenchymal renal neoplasms and are classified as neoplasms of perivascular epithelioid cells (PEComa). AML is…”
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Attenuation of p38α MAPK stress response signaling delays the in vivo aging of skeletal muscle myofibers and progenitor cells by Papaconstantinou, John, Wang, Chen Z, Zhang, Min, Yang, San, Deford, James, Bulavin, Dmitry V, Ansari, Naseem H

“…Functional competence and self-renewal of mammalian skeletal muscle myofibers and progenitor cells declines with age. Progression of the muscle aging phenotype…”
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Therapeutic Strategies to Reduce Burn Wound Conversion by Palackic, Alen, Jay, Jayson W., Duggan, Robert P., Branski, Ludwik K., Wolf, Steven E., Ansari, Naseem, El Ayadi, Amina

“…Burn wound conversion refers to the phenomenon whereby superficial burns that appear to retain the ability to spontaneously heal, convert later into deeper…”
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Topically applied metal chelator reduces thermal injury progression in a rat model of brass comb burn by Wang, Cheng Z, Ayadi, Amina El, Goswamy, Juhi, Finnerty, Celeste C, Mifflin, Randy, Sousse, Linda, Enkhbaatar, Perenlei, Papaconstantinou, John, Herndon, David N, Ansari, Naseem H

“…Highlights • We examine a novel strategy to ameliorate progression of full thickness burn. • The mechanism relies on the use of a metal chelator to control…”
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Metal chelation reduces skin epithelial inflammation and rescues epithelial cells from toxicity due to thermal injury in a rat model by El Ayadi, Amina, Wang, Cheng Z, Zhang, Min, Wetzel, Michael, Prasai, Anesh, Finnerty, Celeste C, Enkhbaatar, Perenlei, Herndon, David N, Ansari, Naseem H

“…Abstract Background One of the most pervasive complications of burn injury is wound progression, characterized by continuous tissue destruction in untreated…”
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Corrigendum to “Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders” [Chem. Biol. Interact. (2011) 330–338] by Srivastava, Satish K., Yadav, Umesh C.S., Reddy, Aramati B.M., Mishra, Rakesh, Saxena, Ashish, Tammali, Ravinder, Shoeb, Mohammad, Ansari, Naseem H., Bhatnagar, Aruni, Petrash, Mark J., Srivastava, Sanjay, Ramana, Kota V.

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Topical Metal Chelation Therapy Ameliorates Oxidation-Induced Toxicity in Diabetic Cataract by Zhang, Min, Shoeb, Mohammad, Liu, Ping, Xiao, Tianlin, Hogan, Dale, Wong, Ira G., Campbell, Gerald A., Ansari, Naseem H.

“…Oxidative stress plays a critical role in cataractogenesis, the leading cause of blindness worldwide. Since transition metals generate reactive oxygen species…”
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Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats by Kalariya, Nilesh M, Reddy, Aramati B M, Ansari, Naseem H, VanKuijk, Frederik J G M, Ramana, Kota V

“…Recent studies indicate that ethyl pyruvate (EP) exerts anti-inflammatory properties; however, the effect of EP on ocular inflammation is not known. The…”
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Pneumocystis carinii infection. Update and review by Wazir, Javed F, Ansari, Naseem A

“…To review and update the literature on current trends with regard to Pneumocystis carinii (jiroveci ) diagnosis, treatment modalities, and its role in human…”
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Differential diagnosis of malignant epithelial tumours in the liver: an immunohistochemical study on liver biopsy material by Al-Muhannadi, Najla, Ansari, Naseem, Brahmi, Urmil, Satir, Ali Abdel

“…A variety of primary and secondary malignant tumours may present in the liver. In clinical practice the most commonly encountered hepatic tumours are primary…”
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Role of Aldehyde Dehydrogenase Isozymes in the Defense of Rat Lens and Human Lens Epithelial Cells against Oxidative Stress by Choudhary, Sanjeev, Xiao, Tianlin, Vergara, Leoncio A, Srivastava, Sanjay, Nees, David, Piatigorsky, Joram, Ansari, Naseem H

“…4-Hydroxynonenal (HNE), a metastable lipid peroxidation product, is highly toxic to various cell types if not detoxified. Because of its constant exposure to…”
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Molecular Cloning and Oxidative Modification of Human Lens ALDH1A1: Implication in Impaired Detoxification of Lipid Aldehydes by Xiao, Tianlin, Shoeb, Mohammad, Siddiqui, M. Saeed, Zhang, Min, Ramana, Kota V., Srivastava, Satish K., Vasiliou, Vasilis, Ansari, Naseem H.

“…Earlier studies showed that human lens ALDH1A1 plays a critical role in protection against oxidative stress-induced cytotoxicity in human lens epithelial cells…”
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Regulation of CD95 (Fas) Expression and Fas-Mediated Apoptotic Signaling in HLE B-3 Cells by 4-Hydroxynonenal by Li, Jie, Sharma, Rajendra, Patrick, Brad, Sharma, Abha, Jeyabal, Prince V. S, Reddy, Prasada M. R. V, Saini, Manjit K, Dwivedi, Seema, Dhanani, Shaheen, Ansari, Naseem H, Zimniak, Piotr, Awasthi, Sanjay, Awasthi, Yogesh C

“…The Fas (apo/CD95) receptor which belongs to the TNF-α family is a transmembrane protein involved in the signaling for apoptosis through the extrinsic pathway…”
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Assessment of methylsulfonylmethane as a permeability enhancer for regional EDTA chelation therapy by Zhang, Min, Wong, Ira G, Gin, Jerry B, Ansari, Naseem H

“…Pharmacologic chelators do not effectively penetrate cell membranes and blood-brain barrier. This study assesses methylsulfonylmethane (MSM) as a permeability…”
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