Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages

Understanding how populations adapt to abrupt environmental change is necessary to predict responses to future challenges, but identifying specific adaptive variants, quantifying their responses to selection and reconstructing their detailed histories is challenging in natural populations. Here, we...

Full description

Saved in:

Bibliographic Details
Published in:	Nature communications Vol. 13; no. 1; p. 1461
Main Authors:	Fulgione, Andrea, Neto, Célia, Elfarargi, Ahmed F., Tergemina, Emmanuel, Ansari, Shifa, Göktay, Mehmet, Dinis, Herculano, Döring, Nina, Flood, Pádraic J., Rodriguez-Pacheco, Sofia, Walden, Nora, Koch, Marcus A., Roux, Fabrice, Hermisson, Joachim, Hancock, Angela M.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 18-03-2022 Nature Publishing Group Nature Portfolio
Subjects:	45 45/23 45/43 45/90 631/181/2474 631/208/182 631/449/1870 64 Adaptation Arabidopsis - genetics Arabidopsis Proteins - genetics Arid climates Aridity Drought Environmental changes Evolution Fitness Flowering Flowers - genetics Genetics Genomes Humanities and Social Sciences Islands Life Sciences MADS Domain Proteins - genetics multidisciplinary Mutation Natural populations Plants genetics Populations Reproductive fitness Science Science (multidisciplinary) Vegetal Biology
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Understanding how populations adapt to abrupt environmental change is necessary to predict responses to future challenges, but identifying specific adaptive variants, quantifying their responses to selection and reconstructing their detailed histories is challenging in natural populations. Here, we use Arabidopsis from the Cape Verde Islands as a model to investigate the mechanisms of adaptation after a sudden shift to a more arid climate. We find genome-wide evidence of adaptation after a multivariate change in selection pressures. In particular, time to flowering is reduced in parallel across islands, substantially increasing fitness. This change is mediated by convergent de novo loss of function of two core flowering time genes: FRI on one island and FLC on the other. Evolutionary reconstructions reveal a case where expansion of the new populations coincided with the emergence and proliferation of these variants, consistent with models of rapid adaptation and evolutionary rescue. Detailing how populations adapted to environmental change is needed to predict future responses, but identifying adaptive variants and detailing their fitness effects is rare. Here, the authors show that parallel loss of FRI and FLC function reduces time to flowering and drives adaptation in a drought prone environment.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 PMCID: PMC8933414
ISSN:	2041-1723 2041-1723
DOI:	10.1038/s41467-022-28800-z