Search Results - "Ansari, Saqib Hussain"

Primary HBB gene mutation severity and long‐term outcomes in a global cohort of β‐thalassaemia by Musallam, Khaled M., Vitrano, Angela, Meloni, Antonella, Addario Pollina, Sebastiano, Di Marco, Vito, Hussain Ansari, Saqib, Filosa, Aldo, Ricchi, Paolo, Ceci, Adriana, Daar, Shahina, Vlachaki, Efthymia, Singer, Sylvia T., Naserullah, Zaki A., Pepe, Alessia, Scondotto, Salvatore, Dardanoni, Gabriella, Karimi, Mehran, El‐Beshlawy, Amal, Hajipour, Mahmoud, Bonifazi, Fedele, Vichinsky, Elliott, Taher, Ali T., Sankaran, Vijay G., Maggio, Aurelio

“…Summary In β‐thalassaemia, the severity of inherited β‐globin gene mutations determines the severity of the clinical phenotype at presentation and subsequent…”
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Hydroxyurea Treated β-Thalassemia Children Demonstrate a Shift in Metabolism Towards Healthy Pattern by Iqbal, Ayesha, Ansari, Saqib Hussain, Parveen, Sadia, Khan, Ishtiaq Ahmad, Siddiqui, Amna Jabbar, Musharraf, Syed Ghulam

“…Augmentation of fetal hemoglobin (HbF) production has been an enduring therapeutic objective in β-thalassemia patients for which hydroxyurea (HU) has largely…”
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Risk of mortality from anemia and iron overload in nontransfusion‐dependent β‐thalassemia by Musallam, Khaled M., Vitrano, Angela, Meloni, Antonella, Pollina, Sebastiano Addario, Karimi, Mehran, El‐Beshlawy, Amal, Hajipour, Mahmoud, Di Marco, Vito, Ansari, Saqib Hussain, Filosa, Aldo, Ricchi, Paolo, Ceci, Adriana, Daar, Shahina, Vlachaki, Efthymia, Singer, Sylvia Titi, Naserullah, Zaki A., Pepe, Alessia, Scondotto, Salvatore, Dardanoni, Gabriella, Bonifazi, Fedele, Sankaran, Vijay G., Vichinsky, Elliott, Taher, Ali T., Maggio, Aurelio

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Survival and causes of death in 2,033 patients with non-transfusion-dependent β-thalassemia by Musallam, Khaled M., Vitrano, Angela, Meloni, Antonella, Pollina, Walter Addario, Karimi, Mehran, El-Beshlawy, Amal, Hajipour, Mahmoud, Di Marco, Vito, Ansari, Saqib Hussain, Filosa, Aldo, Ricchi, Paolo, Ceci, Adriana, Daar, Shahina, Vlachaki, Efthymia, Singer, Sylvia Titi, Naserullah, Zaki A., Pepe, Alessia, Scondotto, Salvatore, Dardanoni, Gabriella, Bonifazi, Fedele, Sankaran, Vijay G., Vichinsky, Elliott, Taher, Ali T., Maggio, Aurelio

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A complication risk score to evaluate clinical severity of thalassaemia syndromes by Vitrano, Angela, Meloni, Antonella, Addario Pollina, Walter, Karimi, Mehran, El‐Beshlawy, Amal, Hajipour, Mahmoud, Di Marco, Vito, Hussain Ansari, Saqib, Filosa, Aldo, Ricchi, Paolo, Ceci, Adriana, Daar, Shahina, Titi Singer, Sylvia, Naserullah, Zaki A., Pepe, Alessia, Scondotto, Salvatore, Dardanoni, Gabriella, Bonifazi, Fedele, Vichinsky, Elliott, Maggio, Aurelio

“…Summary The thalassaemia syndromes (TS) show different phenotype severity. Developing a reliable, practical and global tool to determine disease severity and…”
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Seasonal variations in hematological disorders: A 10‐year single‐center experience by Hassan, Jawad, Adil, Syed Omair, Haider, Zeeshan, Zaheer, Sidra, Anwar, Nida, Nadeem, Muhammad, Ansari, Saqib Hussain, Shamsi, Tahir

“…Aims To assess the seasonal variations in hematological disorders among patients diagnosed on the basis of bone marrow biopsy, who attended National Institute…”
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Challenges of Blood Transfusions in β-Thalassemia during COVID-19 Pandemic in Low Middle-Income Country by Ali, Kashif, Rizvi, Kashif, Ansari, Saqib Hussain, Zahid, Faisal

“…Wuhan, Hubei province, China, was recognized as the center of an epidemic of pneumonia of unknown origin in December 2019. Ultimately, intense focus on the…”
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Impact of hydroxyurea therapy on serum fatty acids of β-thalassemia patients by Iqbal, Ayesha, Siddiqui, Amna Jabbar, Huang, Jian-Hua, Ansari, Saqib Hussain, Musharraf, Syed Ghulam

“…Introduction and objective Fatty acids (FAs) influence cell and tissue metabolism, function, responsiveness to hormonal and other signals in addition to…”
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Peripheral Blood Stem Cell Harvest HPC Count Is an Effective Surrogate Marker for CD34+ Cell Count in Allogeneic Stem Cell Transplant Setting by Jamal, Aisha, Khan, Mohammad Tahir, Parveen, Sadia, Rizvi, Qurratulain, Farzana, Tasneem, Zaidi, Uzma, Borhany, Munira, Siddiqui, Saima, Ansari, Saqib Hussain, Shamsi, Tahir Sultan

“…OBJECTIVE: We assessed the predictive potential of XN-HPC for CD34+ cell count as obtained through Sysmex automated hematology analyzers (XN-1000). METHODS:…”
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Haematopoietic Stem Cell Transplant Trends in Pakistan: Activity Survey from Pakistan Bone Marrow Transplant Group by Ali, Natasha, Iftikhar, Raheel, Ayaz Mir, Muhammad, Bokhari, Syed Waqas, Rehman, Jehanzeb Ur, Zaidi, Uzma, Nasir, Shahzad, Adil, Salman Naseem, Satti, Tariq, Nisa Chaudhry, Qamar Un, Farhan, Muhammad, Farzana, Tasneem, Ghafoor, Tariq, Ahsan, Bushra, Khan, Azhar S., Khan, Farrukh Ali, Fatima, Syeda Itrat, Samad, Shafaq Abdul, Batool, Aliya, Nadeem, Hafiz Muhammad, Abbas Bukhari, Syed Nasir, Ansari, Saqib Hussain, Ahmed, Parvez

“…Pakistan is the fifth most populous country with a population of 225 million and has health expenditure accounting for only 2.8 percent of gross domestic…”
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Early and sustained deep molecular response achieved with nilotinib in high Sokal risk chronic myeloid leukemia patients by Zaidi, Uzma, Kaleem, Bushra, Borhany, Munira, Maqsood, Sidra, Fatima, Naveena, Sufaida, Gul, Ansari, Saqib Hussain, Farzana, Tasneem, Shamsi, Tahir Sultan

“…Nilotinib (Tasigna®) is a second-generation tyrosine kinase inhibitor that shows faster and deeper molecular responses (MR) in comparison to Imatinib as…”
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Random Forest Clustering Identifies Three Subgroups of β-Thalassemia with Distinct Clinical Severity by Vitrano, Angela, Musallam, Khaled M., Meloni, Antonella, Addario Pollina, Sebastiano, Karimi, Mehran, El-Beshlawy, Amal, Hajipour, Mahmoud, Di Marco, Vito, Ansari, Saqib Hussain, Filosa, Aldo, Ricchi, Paolo, Ceci, Adriana, Daar, Shahina, Vlachaki, Efthymia, Singer, Sylvia Titi, Naserullah, Zaki A., Pepe, Alessia, Scondotto, Salvatore, Dardanoni, Gabriella, Bonifazi, Fedele, Sankaran, Vijay G., Vichinsky, Elliott, Taher, Ali T., Maggio, Aurelio

“…In this work, we aimed to establish subgroups of clinical severity in a global cohort of β-thalassemia through unsupervised random forest (RF) clustering. We…”
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Transcobalamin deficiency — a rare genetic defect in transportation of cobalamin; case report by Iqbal, Neelofar, Meghani, Marium Ali, Khalid, Wajeeha, Ansari, Ali Hussain, Ansari, Muhammad Usman Hussain, Ansari, Saqib Hussain

“…Background Vitamin B12 is primarily transported from plasma to cells by Transcobalamin. Deficiency of Transcobalamin is a rare autosomal recessive disorder…”
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Reflection of treatment proficiency of hydroxyurea treated β-thalassemia serum samples through nuclear magnetic resonance based metabonomics by Khalid, Ayesha, Siddiqui, Amna Jabbar, Ansari, Saqib Hussain, Musharraf, Syed Ghulam

“…β-Thalassemia is a widespread autosomal recessive blood disorder found in most parts of the world. Fetal hemoglobin (HbF), a form of hemoglobin is found in…”
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β-Thalassemia Patients Revealed a Significant Change of Untargeted Metabolites in Comparison to Healthy Individuals by Musharraf, Syed Ghulam, Iqbal, Ayesha, Ansari, Saqib Hussain, Parveen, Sadia, Khan, Ishtiaq Ahmad, Siddiqui, Amna Jabbar

“…β-Thalassemia is one of the most prevalent forms of congenital blood disorders characterized by reduced hemoglobin levels with severe complications, affecting…”
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Antibiotic Stewardship: A Handshaking Strategy Among Physicians and Pharmacists to Improve therapeutic Outcomes in Hematology-Oncology by Ali, Kashif, Shakeel, Sadia, Dhiloo, Azizullah Khan, Wajdi, Mehwish, Anjum, Fakhsheena, Ansari, Saqib Hussain

“…Background: Infections are highly susceptible in patients with hematological malignancies due to immune suppression, immunosuppressive therapies and disease…”
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Molecular pathology and computational profiling of Janus kinase 2 (JAK2) mutation in acute lymphoblastic leukemia: insights from a Pakistani cohort by Maqsood, Sidra, Ansari, Saqib Hussain, Mushtaq, Mamona, Abbas, Azhar, Waryah, Ali Muhammad, Haq, Zaheer Ul

“…JAK2 mutation plays a clinically significant role in the pathogenesis of acute lymphoblastic leukemia (ALL) by enhancing its oncogenicity. The study aimed to…”
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A scoping review on the obstacles faced by beta thalassemia major patients in Pakistan- Matter of policy investment by Ansari, Ali Hussain, Ansari, Saqib Hussain, Salman, Mubarak Jabeen, Ansari, Muhammad Usman Hussain, Jabeen, Rawshan

“…Beta-thalassemia major (β-TM) is a genetic disorder, prevalent especially in the Mediterranean region, Southeast Asia, and the Indian subcontinent. With…”
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Development of a Thalassemia International Prognostic Scoring System (TIPSS) by Vitrano, Angela, Musallam, Khaled M., Meloni, Antonella, Karimi, Mehran, Daar, Shahina, Ricchi, Paolo, Costantini, Silvia, Vlachaki, Efthymia, Di Marco, Vito, El-Beshlawy, Amal, Hajipour, Mahmoud, Ansari, Saqib Hussain, Filosa, Aldo, Ceci, Adriana, Singer, Sylvia Titi, Naserullah, Zaki A., Pepe, Alessia, Cademartiri, Filippo, Pollina, Sebastiano Addario, Scondotto, Salvatore, Dardanoni, Gabriella, Bonifazi, Fedele, Sankaran, Vijay G., Vichinsky, Elliott, Taher, Ali T., Maggio, Aurelio

“…A prognostic scoring system that can differentiate β-thalassemia patients based on mortality risk is lacking. We analysed data from 3145 β-thalassemia patients…”
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Frequency of Alpha Thalassaemia in homozygous Beta Thalassaemia paediatric patients and its clinical impact at a blood disease centre in Karachi, Pakistan by Hassan, Jawad, Nadeem, Muhammad, Ansari, Saqib Hussain, Ahmed, Shariq, Parveen, Sadia, Shamsi, Tahir

“…To find frequency ofalpha Thalsaemia nhomozygous beta Thalsaemia patients, and to se any difernce infrequency and age ofirst ransfusion and mean haemoglobin…”
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