Search Results - "Ansari, Asgar Hussain"

Identification of G-quadruplex structures in MALAT1 lncRNA that interact with nucleolin and nucleophosmin by Ghosh, Arpita, Pandey, Satya Prakash, Joshi, Dheeraj Chandra, Rana, Priya, Ansari, Asgar Hussain, Sundar, Jennifer Seematti, Singh, Praveen, Khan, Yasmeen, Ekka, Mary Krishna, Chakraborty, Debojyoti, Maiti, Souvik

“…Nuclear-retained long non-coding RNAs (lncRNAs) including MALAT1 have emerged as critical regulators of many molecular processes including transcription,…”
Get full text

TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes by Aich, Meghali, Ansari, Asgar Hussain, Ding, Li, Iesmantavicius, Vytautas, Paul, Deepanjan, Choudhary, Chunaram, Maiti, Souvik, Buchholz, Frank, Chakraborty, Debojyoti

“…Embryonic stem cells (ESCs) can undergo lineage-specific differentiation, giving rise to different cell types that constitute an organism. Although roles of…”
Get full text

PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics by Acharya, Sundaram, Ansari, Asgar Hussain, Kumar Das, Prosad, Hirano, Seiichi, Aich, Meghali, Rauthan, Riya, Mahato, Sudipta, Maddileti, Savitri, Sarkar, Sajal, Kumar, Manoj, Phutela, Rhythm, Gulati, Sneha, Rahman, Abdul, Goel, Arushi, Afzal, C., Paul, Deepanjan, Agrawal, Trupti, Pulimamidi, Vinay Kumar, Jalali, Subhadra, Nishimasu, Hiroshi, Mariappan, Indumathi, Nureki, Osamu, Maiti, Souvik, Chakraborty, Debojyoti

“…The clinical success of CRISPR therapies hinges on the safety and efficacy of Cas proteins. The Cas9 from Francisella novicida (FnCas9) is highly precise, with…”
Get full text

Small molecule quercetin binds MALAT1 triplex and modulates its cellular function by Rakheja, Isha, Ansari, Asgar Hussain, Ray, Arjun, Chandra Joshi, Dheeraj, Maiti, Souvik

“…The triple-helix structure at the 3′ end of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long non-coding RNA, has been considered to be a…”
Get full text

Diagnostic and Prognostic Potential of MiR-379/656 MicroRNA Cluster in Molecular Subtypes of Breast Cancer by Lal, Megha, Ansari, Asgar Hussain, Agrawal, Anurag, Mukhopadhyay, Arijit

“…Introduction: Breast cancer is the most frequently diagnosed cancer globally and is one of the most important contributors to cancer-related deaths. Earlier…”
Get full text

Fine-tuning miR-21 expression and inhibition of EMT in breast cancer cells using aromatic-neomycin derivatives by Ghosh, Arpita, Ranjan, Nihar, Jiang, Liuwei, Ansari, Asgar Hussain, Degyatoreva, Natalya, Ahluwalia, Shivaksh, Arya, Dev P., Maiti, Souvik

“…MicroRNAs (miRs) are a class of endogenously expressed non-coding RNAs that negatively regulate gene expression within cells and participate in maintaining…”
Get full text

Human Brain Shows Recurrent Non-Canonical MicroRNA Editing Events Enriched for Seed Sequence with Possible Functional Consequence by Paul, Deepanjan, Ansari, Asgar Hussain, Lal, Megha, Mukhopadhyay, Arijit

“…RNA editing is a post-transcriptional modification, which can provide tissue-specific functions not encoded in DNA. Adenosine-to-inosine is the predominant…”
Get full text

Human brain harbors single nucleotide somatic variations in functionally relevant genes possibly mediated by oxidative stress by Sharma, Anchal, Ansari, Asgar Hussain, Kumari, Renu, Pandey, Rajesh, Rehman, Rakhshinda, Mehani, Bharati, Varma, Binuja, Desiraju, Bapu K., Mabalirajan, Ulaganathan, Agrawal, Anurag, Mukhopadhyay, Arijit

“…Somatic variation in DNA can cause cells to deviate from the preordained genomic path in both disease and healthy conditions. Here, using exome sequencing of…”
Get full text

Human brain harbors single nucleotide somatic variations in functionally relevant genes possibly mediated by oxidative stress [version 2; peer review: 2 approved with reservations] by Sharma, Anchal, Ansari, Asgar Hussain, Kumari, Renu, Pandey, Rajesh, Rehman, Rakhshinda, Mehani, Bharati, Varma, Binuja, Desiraju, Bapu K, Mabalirajan, Ulaganathan, Agrawal, Anurag, Mukhopadhyay, Arijit

“…Somatic variation in DNA can cause cells to deviate from the preordained genomic path in both disease and healthy conditions. Here, using exome sequencing of…”
Get full text

Rapid and accurate nucleobase detection using FnCas9 and its application in COVID-19 diagnosis by Azhar, Mohd, Phutela, Rhythm, Kumar, Manoj, Ansari, Asgar Hussain, Rauthan, Riya, Gulati, Sneha, Sharma, Namrata, Sinha, Dipanjali, Sharma, Saumya, Singh, Sunaina, Acharya, Sundaram, Sarkar, Sajal, Paul, Deepanjan, Kathpalia, Poorti, Aich, Meghali, Sehgal, Paras, Ranjan, Gyan, Bhoyar, Rahul C., Singhal, Khushboo, Lad, Harsha, Patra, Pradeep Kumar, Makharia, Govind, Chandak, Giriraj Ratan, Pesala, Bala, Chakraborty, Debojyoti, Maiti, Souvik

“…Rapid detection of DNA/RNA pathogenic sequences or variants through point-of-care diagnostics is valuable for accelerated clinical prognosis, as witnessed…”
Get full text

Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing by Acharya, Sundaram, Mishra, Arpit, Paul, Deepanjan, Ansari, Asgar Hussain, Azhar, Mohd, Kumar, Manoj, Rauthan, Riya, Sharma, Namrata, Aich, Meghali, Sinha, Dipanjali, Sharma, Saumya, Jain, Shivani, Ray, Arjun, Jain, Suman, Ramalingam, Sivaprakash, Maiti, Souvik, Chakraborty, Debojyoti

“…Genome editing using the CRISPR/Cas9 system has been used to make precise heritable changes in the DNA of organisms. Although the widely used Streptococcus…”
Get full text

Alternative splicing modulation mediated by G-quadruplex structures in MALAT1 lncRNA by Ghosh, Arpita, Pandey, Satya Prakash, Ansari, Asgar Hussain, Sundar, Jennifer Seematti, Singh, Praveen, Khan, Yasmeen, Ekka, Mary Krishna, Chakraborty, Debojyoti, Maiti, Souvik

“…MALAT1, an abundant lncRNA specifically localized to nuclear speckles, regulates alternative-splicing (AS). The molecular basis of its role in AS remains…”
Get full text

Retracted: Alternative splicing modulation mediated by G-quadruplex structures in MALAT1 lncRNA by Ghosh, Arpita, Pandey, Satya Prakash, Ansari, Asgar Hussain, Sundar, Jennifer Seematti, Singh, Praveen, Khan, Yasmeen, Ekka, Mary Krishna, Chakraborty, Debojyoti, Maiti, Souvik

Get full text

Human brain harbors single nucleotide somatic variations in functionally relevant genes possibly mediated by oxidative stress by Sharma, Anchal, Ansari, Asgar Hussain, Kumari, Renu, Pandey, Rajesh, Rehman, Rakhshinda, Mehani, Bharati, Varma, Binuja, Desiraju, Bapu K, Mabalirajan, Ulaganathan, Agrawal, Anurag, Mukhopadhyay, Arijit

“…Somatic variation in DNA can cause cells to deviate from the preordained genomic path in both disease and healthy conditions. Here, using exome sequencing of…”
Get full text