Search Results - "Anraku, Tsuyoshi"

In vivo bladder selectivity of imidafenacin, a novel antimuscarinic agent, assessed by using an effectiveness index for bladder capacity in rats by Yamazaki, Takanobu, Muraki, Yukiko, Anraku, Tsuyoshi

“…Imidafenacin (KRP-197) is a novel antimuscarinic agent for overactive bladder treatment. The inhibitory effect of imidafenacin on detrusor contraction has been…”
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Anoxia/reoxygenation enhances spontaneous contractile activity via TRPA1 channel and COX2 activation in isolated rat whole bladder by Anraku, Tsuyoshi

“…Purpose Bladder ischemia/reperfusion is an important etiologic factor for overactive bladder disease. The occurrence of this disease is closely associated with…”
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Ibudilast, a mixed PDE3/4 inhibitor, causes a selective and nitric oxide/cGMP-independent relaxation of the intracranial vertebrobasilar artery by Yamazaki, Takanobu, Anraku, Tsuyoshi, Matsuzawa, Shigeki

“…Ibudilast, a mixed phosphodiesterase (PDE) 3/4 inhibitor, is a cerebral vasodilator widely used in Japan for treating post-stroke dizziness. However, little…”
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Withdrawal from chronic morphine administration causes prolonged enhancement of immobility in rat forced swimming test by ANRAKU, Tsuyoshi, IKEGAYA, Yuji, MATSUKI, Norio, NISHIYAMA, Nobuyoshi

“…Opiate-dependent subjects experience severe depression as one of the subjective symptoms during withdrawal. No experimental work, however, has focused on the…”
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Neuroprotective effects of KCL-440, a new poly(ADP-ribose) polymerase inhibitor, in the rat middle cerebral artery occlusion model by Ikeda, Yasuhiko, Hokamura, Kazuya, Kawai, Tomoyuki, Ishiyama, Junichi, Ishikawa, Kumi, Anraku, Tsuyoshi, Uno, Takashi, Umemura, Kazuo

“…It is reported that ischemic brain injury is mediated by the activation of poly(ADP-ribose) polymerase (PARP). In this study, we examined the pharmacological…”
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Design and synthesis of novel 7-heterocycle-6-trifluoromethyl-3-oxoquinoxaline-2-carboxylic acids bearing a substituted phenyl group as superior AMPA receptor antagonists with good physicochemical properties by Takano, Yasuo, Shiga, Futoshi, Asano, Jun, Hori, Wataru, Fukuchi, Kazunori, Anraku, Tsuyoshi, Uno, Takashi

“…We describe the design, synthesis, and physicochemical properties and biological properties of a novel series of…”
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Design and synthesis of novel 7-heterocycle-6-trifluoromethyl-3-oxoquinoxaline-2-carboxylic acids bearing a substituted phenyl group as superior AMPAreceptor antagonists with good physicochemical properties by TAKANO, Yasuo, SHIGA, Futoshi, ASANO, Jun, HORI, Wataru, FUKUCHI, Kazunori, ANRAKU, Tsuyoshi, UNO, Takashi

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Neuroprotective effects of KCL-440, a new poly(ADP-ribose)polymerase inhibitor, on a rat model of middle cerebral artery occlusion by Yasuhko Ikeda, Kazuya Hokamura, Kazunao Kondo, Yasuhiro Suzuki, Tomoyuki Kawai, Tsuyoshi Anraku, Takashi Uno, Kazuo Umemura

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Chronic interferon- α treatment leads to adaptations of opioid receptors-mediated intracellular cAMP pathway in human neuroblastoma SK-N-SH cells by Nishiyama, N

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Withdrawal from Repeated and Chronic Morphine Administration Cause Differential Changes in Immobility in Rat Forced Swimming Test by Tsuyoshi Anraku, Yuji Ikegaya, Norio Matsuki, Nobuyoshi Nishiyama

“…Opiate-dependent subjects have experience of severe depression as one of subjective symptomatology during the drug withdrawal. No work, however, has focused on…”
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