Search Results - "Anraku, Kensaku"
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A clue to unprecedented strategy to HIV eradication: “Lock-in and apoptosis”
Published in Scientific reports (21-08-2017)“…Despite the development of antiretroviral therapy against HIV, eradication of the virus from the body, as a means to a cure, remains in progress. A “kick and…”
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Structural insight into host plasma membrane association and assembly of HIV-1 matrix protein
Published in Scientific reports (04-08-2021)“…Oligomerization of Pr55 Gag is a critical step of the late stage of the HIV life cycle. It has been known that the binding of IP6, an abundant endogenous…”
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Highly Sensitive Analysis of the Interaction between HIV-1 Gag and Phosphoinositide Derivatives Based on Surface Plasmon Resonance
Published in Biochemistry (Easton) (29-06-2010)“…Human immunodeficiency virus type 1 (HIV-1) Gag protein is the principal structural component of the HIV particle. Localization of the Pr55Gag protein to the…”
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Significance of Circulating Remnant Lipoprotein Cholesterol Levels Measured by Homogeneous Assay in Patients with Type 2 Diabetes
Published in Biomolecules (Basel, Switzerland) (01-03-2023)“…Remnant lipoproteins (RLs), which are typically present at high concentrations in patients with type 2 diabetes mellitus (T2DM), are associated with…”
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Design and synthesis of lipid-coupled inositol 1,2,3,4,5,6-hexakisphosphate derivatives exhibiting high-affinity binding for the HIV-1 MA domain
Published in Organic & biomolecular chemistry (21-07-2014)“…The precursor of Gag protein (Pr55(Gag)) of human immunodeficiency virus, the principal structural component required for virus assembly, is known to bind…”
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Differences in reaction specificity toward lipoprotein X and abnormal LDL among 6 homogeneous assays for LDL-cholesterol
Published in Clinica chimica acta (15-01-2015)“…We investigated the reaction specificity toward cholesterol in lipoprotein X (Lp-X) and abnormal LDL among 6 homogeneous assays for low-density lipoprotein…”
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Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain
Published in Bioorganic & medicinal chemistry (15-11-2011)“…A bifunctional molecule containing biotin and d-myo-inositol 1,3,4,5-tetrakisphosphate was synthesized. This molecule was designed on the basis of X-ray…”
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Removal of toxin (tetrodotoxin) from puffer ovary by traditional fermentation
Published in Toxins (18-01-2013)“…The amounts of puffer toxin (tetrodotoxin, TTX) extracted from the fresh and the traditional Japanese salted and fermented "Nukazuke" and "Kasuzuke" ovaries of…”
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Design and synthesis of biotinylated inositol phosphates relevant to the biotin-avidin techniques
Published in Organic & biomolecular chemistry (01-01-2008)“…Six bifunctional molecules containing biotin and various inositol phosphates were synthesized. These compounds were designed on the basis of X-ray structures…”
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HIV‐1 Gag MA domain binds to cardiolipin in a binding mode distinct from virus assemble mediator PI(4,5)P2
Published in Chemical biology & drug design (01-01-2024)“…The human immunodeficiency virus type 1 (HIV‐1) Gag protein is responsible for facilitating HIV‐1 virion assembly and budding. Our study demonstrates that…”
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HIV-1 Gag MA domain binds to cardiolipin in a binding mode distinct from virus assemble mediator PI(4,5)P 2
Published in Chemical biology & drug design (01-01-2024)“…The human immunodeficiency virus type 1 (HIV-1) Gag protein is responsible for facilitating HIV-1 virion assembly and budding. Our study demonstrates that…”
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The design and synthesis of an α-Gal trisaccharide epitope that provides a highly specific anti-Gal immune response
Published in Organic & biomolecular chemistry (05-04-2017)“…Carbohydrate antigens displaying Galα(1,3)Gal epitopes are recognized by naturally occurring antibodies in humans. These anti-Gal antibodies comprise up to 1%…”
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Development of chimeric receptor activator of nuclear factor‐kappa B with glutathione S‐transferase in the extracellular domain: Artificial switch in a membrane receptor
Published in Chemical biology & drug design (01-04-2022)“…Various chimeric receptors have been developed and used for biological experiments. In the present study, we constructed three types of chimeric receptor…”
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14
A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior
Published in Chemical communications (Cambridge, England) (18-07-2017)“…A method for potentiating the response to an anti-cocaine vaccine by leveraging xenoreactive antibodies against the carbohydrate epitope Galα1,3-Gal (GAL) was…”
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15
A homogeneous assay to determine high-density lipoprotein subclass cholesterol in serum
Published in Analytical biochemistry (15-01-2021)“…Existing methods to measure high-density lipoprotein cholesterol (HDL-C) subclasses (HDL2-C and HDL3-C) are complex and require proficiency, and thus there is…”
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Facile Synthesis of 2-Phenylquinoline-4-carboxamide Derivatives with Variant Structural Features
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Quantitative analysis of toxin extracts from various tissues of wild and cultured puffer fish by an electrophysiological method
Published in Toxicon (Oxford) (15-03-2008)“…We observed the effects of the toxin extracted from various tissues of wild and cultured puffer fish on voltage-dependent sodium current ( I Na) using single…”
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