Search Results - "Annunziata, M."

Proteasome inhibitors: structure and function by Nunes, Ana T., Annunziata, Christina M.

“…Since 2003, the US Food and Drug Administration approval of bortezomib, a proteasome inhibitor, has changed the management of hematologic malignancies and…”
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Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline by Konstantinopoulos, Panagiotis A, Norquist, Barbara, Lacchetti, Christina, Armstrong, Deborah, Grisham, Rachel N, Goodfellow, Paul J, Kohn, Elise C, Levine, Douglas A, Liu, Joyce F, Lu, Karen H, Sparacio, Dorinda, Annunziata, Christina M

“…To provide recommendations on genetic and tumor testing for women diagnosed with epithelial ovarian cancer based on available evidence and expert consensus. A…”
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Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression by Rice, Christopher M., Davies, Luke C., Subleski, Jeff J., Maio, Nunziata, Gonzalez-Cotto, Marieli, Andrews, Caroline, Patel, Nimit L., Palmieri, Erika M., Weiss, Jonathan M., Lee, Jung-Min, Annunziata, Christina M., Rouault, Tracey A., Durum, Scott K., McVicar, Daniel W.

“…Neutrophils are a vital component of immune protection, yet in cancer they may promote tumour progression, partly by generating reactive oxygen species (ROS)…”
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Combination of PARP Inhibitor Olaparib, and PD-L1 Inhibitor Durvalumab, in Recurrent Ovarian Cancer: a Proof-of-Concept Phase II Study by Lampert, Erika J, Zimmer, Alexandra, Padget, Michelle, Cimino-Mathews, Ashley, Nair, Jayakumar R, Liu, Yingmiao, Swisher, Elizabeth M, Hodge, James W, Nixon, Andrew B, Nichols, Erin, Bagheri, Mohammad H, Levy, Elliott, Radke, Marc R, Lipkowitz, Stanley, Annunziata, Christina M, Taube, Janis M, Steinberg, Seth M, Lee, Jung-Min

“…Preclinical studies suggest PARP inhibition (PARPi) induces immunostimulatory micromilieu in ovarian cancer thus complementing activity of immune checkpoint…”
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The Betti base: the awakening of a sleeping beauty by Cardellicchio, Cosimo, Capozzi, Maria Annunziata M., Naso, Francesco

“…The multicomponent reaction between 2-naphthol, aryl aldehydes and ammonia or amines yields aminobenzylnaphthols in a process known as the Betti reaction,…”
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Infrared Irradiation‐Assisted Solvent‐Free Pd‐Catalyzed (Hetero)aryl‐aryl Coupling via C−H Bond Activation by Albano, Gianluigi, Decandia, Gianfranco, Capozzi, Maria Annunziata M., Zappimbulso, Nicola, Punzi, Angela, Farinola, Gianluca M.

“…The increasing attention towards environmentally friendly synthetic protocols has boosted studies directed to the development of green and sustainable methods…”
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A comparative screening of laccase-mediator systems by white-rot fungi laccases for biocatalytic benzyl alcohol oxidation by Marino, Ivana, Pignataro, Eugenia, Danzi, Donatella, Cellini, Francesco, Cardellicchio, Cosimo, Biundo, Antonino, Pisano, Isabella, Capozzi, Maria Annunziata M.

“…Production of value-added compounds from waste materials is of utmost importance for the development of a sustainable society especially regarding their use as…”
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Solvent‐free Reactions for the Synthesis of Indolenine‐based Squaraines and Croconaines: Comparison of Thermal Heating, Mechanochemical Milling, and IR Irradiation by Zappimbulso, Nicola, Capozzi, Maria Annunziata M., Porcheddu, Andrea, Farinola, Gianluca M., Punzi, Angela

“…Squaraines and croconaines are organic dyes characterized by intense absorption in the visible or near‐infrared spectral regions with applications ranging from…”
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Solvent-Free Pd-Catalyzed Heteroaryl–Aryl Coupling via C–H Bond Activation for the Synthesis of Extended Heteroaromatic Conjugated Molecules by Punzi, Angela, Capozzi, Maria Annunziata M, Di Noja, Simone, Ragni, Roberta, Zappimbulso, Nicola, Farinola, Gianluca M

“…Direct arylation of thienopyrrolodione, diketopyrrolopyrroles, benzodithiophene derivatives, and fluorinated heteroarenes with functionalized aryl iodides is…”
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Prexasertib, a cell cycle checkpoint kinase 1 and 2 inhibitor, in BRCA wild-type recurrent high-grade serous ovarian cancer: a first-in-class proof-of-concept phase 2 study by Lee, Jung-Min, Nair, Jayakumar, Zimmer, Alexandra, Lipkowitz, Stanley, Annunziata, Christina M, Merino, Maria J, Swisher, Elizabeth M, Harrell, Maria I, Trepel, Jane B, Lee, Min-Jung, Bagheri, Mohammad H, Botesteanu, Dana-Adriana, Steinberg, Seth M, Minasian, Lori, Ekwede, Irene, Kohn, Elise C

“…High-grade serous ovarian carcinoma is characterised by TP53 mutations, DNA repair defects, and genomic instability. We hypothesised that prexasertib…”
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Poly (ADP-Ribose) Polymerase as a Novel Therapeutic Target in Cancer by ANNUNZIATA, Christina M, O'SHAUGHNESSY, Joyce

“…Cancer chemotherapy exploits limitations in repairing DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within…”
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Aggregation Modes of Chiral Diketopyrrolo[3,4‐c]pyrrole Dyes in Solution and Thin Films by Albano, Gianluigi, Zinna, Francesco, Urraci, Francesco, Capozzi, Maria Annunziata M., Pescitelli, Gennaro, Punzi, Angela, Di Bari, Lorenzo, Farinola, Gianluca M.

“…The chiroptical features of chiral diketopyrrolo[3,4‐c]pyrrole (DPP) derivatives have been only marginally investigated to date. In this regard, we have…”
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1-[(1S)-(4-Fluorophenyl)-((1′S)-1′-naphthalen-1-yl-ethylamino)-methyl]-naphthalen-2-trifluoromethanesulfonate by Cardellicchio, Cosimo, Capozzi, Maria Annunziata M.

“…The complex structure of aminobenzylnaphthols can be easily obtained with the useful Betti reaction. These valuable compounds can give rise to chiral…”
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Radiation Therapy for Cervical Cancer: Executive Summary of an ASTRO Clinical Practice Guideline by Chino, Junzo, Annunziata, Christina M., Beriwal, Sushil, Bradfield, Lisa, Erickson, Beth A., Fields, Emma C., Fitch, KathrynJane, Harkenrider, Matthew M., Holschneider, Christine H., Kamrava, Mitchell, Leung, Eric, Lin, Lilie L., Mayadev, Jyoti S., Morcos, Marc, Nwachukwu, Chika, Petereit, Daniel, Viswanathan, Akila N.

“…This guideline reviews the evidence and provides recommendations for the indications and appropriate techniques of radiation therapy (RT) in the treatment of…”
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Chiral Diketopyrrolo[3,4‐c]pyrrole‐1,2,3‐1H‐triazole Dyes with Highly Tuneable Properties in Solution and Thin Films by Albano, Gianluigi, Zinna, Francesco, Taddeucci, Andrea, Capozzi, Maria Annunziata M., Pescitelli, Gennaro, Punzi, Angela, Di Bari, Lorenzo, Farinola, Gianluca M.

“…We have studied the impact of achiral substituents on the chiral supramolecular architectures of diketopyrrolo[3,4‐c]pyrrole‐1,2,3‐1H‐triazole (DPP) dyes. We…”
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(S,S)-1-(Phenyl((1′-4-nitrophenyl-ethyl)amino)methyl)-2-naphthol by Capozzi, Maria Annunziata M., Cardellicchio, Cosimo

“…The Betti reaction of 2-naphthol, benzaldehyde and (S)-1-(4-nitrophenyl)ethylamine without any solvent gave the corresponding aminobenzylnaphthol, that is the…”
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Defining Hospital Anxiety and Depression Scale (HADS) structure by confirmatory factor analysis: a contribution to validation for oncological settings by Annunziata, M.A., Muzzatti, B., Altoè, G.

“…Despite its popularity, not a definitive word has yet been said about the latent structure of the Hospital Anxiety and Depression Scale (HADS). The present…”
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Driving Immune Responses in the Ovarian Tumor Microenvironment by Ning, Franklin, Cole, Christopher B, Annunziata, Christina M

“…Ovarian cancer is the leading cause of death among gynecological neoplasms, with an estimated 14,000 deaths in 2019. First-line treatment options center around…”
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Chiral Diketopyrrolo[3,4‐c]pyrrole‐1,2,3‐1H‐triazole Dyes with Highly Tuneable Properties in Solution and Thin Films by Albano, Gianluigi, Zinna, Francesco, Taddeucci, Andrea, Capozzi, Maria Annunziata M., Pescitelli, Gennaro, Punzi, Angela, Di Bari, Lorenzo, Farinola, Gianluca M.

“…Invited for the cover of this issue are the research groups of Lorenzo Di Bari at the University of Pisa and Gianluca Maria Farinola at the University of Bari…”
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Antiproliferative Activity of Aminobenzylnaphthols Deriving from the Betti Reaction by Mallamaci, Rosanna, Capozzi, Maria Annunziata M., Cardellicchio, Cosimo

“…Two aminobenzylnaphthols, which are representative items of the family of compounds synthesized with the Betti reaction, were investigated as antiproliferative…”
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