Search Results - "Annis, David A."

Hydrogen Peroxide Induces α-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes by Stemberger, Megan B, Ju, Julia A, Thompson, Keyata N, Mathias, Trevor J, Jerrett, Alexandra E, Chang, Katarina T, Ory, Eleanor C, Annis, David A, Mull, Makenzy L, Gilchrist, Darin E, Vitolo, Michele I, Martin, Stuart S

“…Levels of hydrogen peroxide are highly elevated in the breast tumor microenvironment compared to normal tissue. Production of hydrogen peroxide is implicated…”
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237-LB: Identification of Small Molecules That Increase Beta-Cell Mass in Hyperinsulinemic Zebrafish Alström Syndrome Model by DUNLEAVEY, JESSICA, ANNIS, DAVID A., HOSTELLEY, TIMOTHY L., ZAGHLOUL, NORANN A.

“…Alström syndrome is an autosomal recessive obesity ciliopathy caused by loss-of-function mutations in the ALMS1 gene. In addition to multi-organ dysfunction,…”
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Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca2+ signals that are inhibited by oncogenic KRas by Pratt, Stephen J. P., Lee, Rachel M., Chang, Katarina T., Hernández-Ochoa, Erick O., Annis, David A., Ory, Eleanor C., Thompson, Keyata N., Bailey, Patrick C., Mathias, Trevor J., Ju, Julia A., Vitolo, Michele I., Schneider, Martin F., Stains, Joseph P., Ward, Christopher W., Martin, Stuart S.

“…Changes in the mechanical microenvironment and mechanical signals are observed during tumor progression, malignant transformation, and metastasis. In this…”
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Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca 2+ signals that are inhibited by oncogenic KRas by Pratt, Stephen J P, Lee, Rachel M, Chang, Katarina T, Hernández-Ochoa, Erick O, Annis, David A, Ory, Eleanor C, Thompson, Keyata N, Bailey, Patrick C, Mathias, Trevor J, Ju, Julia A, Vitolo, Michele I, Schneider, Martin F, Stains, Joseph P, Ward, Christopher W, Martin, Stuart S

“…Changes in the mechanical microenvironment and mechanical signals are observed during tumor progression, malignant transformation, and metastasis. In this…”
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Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells by Chang, Katarina T, Thompson, Keyata N, Pratt, Stephen J P, Ju, Julia A, Lee, Rachel M, Mathias, Trevor J, Mull, Makenzy L, Annis, David A, Ory, Eleanor C, Stemberger, Megan B, Vitolo, Michele I, Martin, Stuart S

“…Cytoskeletal remodeling in circulating tumor cells (CTCs) facilitates metastatic spread. Previous oncology studies examine sustained aberrant calcium (Ca )…”
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Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling by Mathias, Trevor J, Ju, Julia A, Lee, Rachel M, Thompson, Keyata N, Mull, Makenzy L, Annis, David A, Chang, Katarina T, Ory, Eleanor C, Stemberger, Megan B, Hotta, Takashi, Ohi, Ryoma, Vitolo, Michele I, Moutin, Marie-Jo, Martin, Stuart S

“…Post-translational modifications (PTMs) of the microtubule network impart differential functions across normal cell types and their cancerous counterparts. The…”
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