Search Results - "Annicotte, Jean‐Sébastien"

The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids by Ducastel, Sarah, Touche, Véronique, Trabelsi, Mohamed-Sami, Boulinguiez, Alexis, Butruille, Laura, Nawrot, Margaux, Peschard, Simon, Chávez-Talavera, Oscar, Dorchies, Emilie, Vallez, Emmanuelle, Annicotte, Jean-Sébastien, Lancel, Steve, Briand, Olivier, Bantubungi, Kadiombo, Caron, Sandrine, Bindels, Laure B., Delzenne, Nathalie M., Tailleux, Anne, Staels, Bart, Lestavel, Sophie

“…The gut microbiota participates in the control of energy homeostasis partly through fermentation of dietary fibers hence producing short-chain fatty acids…”
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E2F transcription factor-1 regulates oxidative metabolism by Blanchet, Emilie, Annicotte, Jean-Sébastien, Fajas, Lluis, Lagarrigue, Sylviane, Aguilar, Victor, Clapé, Cyrielle, Chavey, Carine, Fritz, Vanessa, Casas, François, Apparailly, Florence, Auwerx, Johan

“…Cells respond to stress by coordinating proliferative and metabolic pathways. Starvation restricts cell proliferative (glycolytic) and activates energy…”
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Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver by Dubois, Vanessa, Gheeraert, Céline, Vankrunkelsven, Wouter, Dubois‐Chevalier, Julie, Dehondt, Hélène, Bobowski‐Gerard, Marie, Vinod, Manjula, Zummo, Francesco Paolo, Güiza, Fabian, Ploton, Maheul, Dorchies, Emilie, Pineau, Laurent, Boulinguiez, Alexis, Vallez, Emmanuelle, Woitrain, Eloise, Baugé, Eric, Lalloyer, Fanny, Duhem, Christian, Rabhi, Nabil, van Kesteren, Ronald E, Chiang, Cheng‐Ming, Lancel, Steve, Duez, Hélène, Annicotte, Jean‐Sébastien, Paumelle, Réjane, Vanhorebeek, Ilse, Van den Berghe, Greet, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme

“…Liver injury triggers adaptive remodeling of the hepatic transcriptome for repair/regeneration. We demonstrate that this involves particularly profound…”
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Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR by Mogilenko, Denis A., Haas, Joel T., L’homme, Laurent, Fleury, Sébastien, Quemener, Sandrine, Levavasseur, Matthieu, Becquart, Coralie, Wartelle, Julien, Bogomolova, Alexandra, Pineau, Laurent, Molendi-Coste, Olivier, Lancel, Steve, Dehondt, Hélène, Gheeraert, Celine, Melchior, Aurelie, Dewas, Cédric, Nikitin, Artemii, Pic, Samuel, Rabhi, Nabil, Annicotte, Jean-Sébastien, Oyadomari, Seiichi, Velasco-Hernandez, Talia, Cammenga, Jörg, Foretz, Marc, Viollet, Benoit, Vukovic, Milica, Villacreces, Arnaud, Kranc, Kamil, Carmeliet, Peter, Marot, Guillemette, Boulter, Alexis, Tavernier, Simon, Berod, Luciana, Longhi, Maria P., Paget, Christophe, Janssens, Sophie, Staumont-Sallé, Delphine, Aksoy, Ezra, Staels, Bart, Dombrowicz, David

“…Innate immune responses are intricately linked with intracellular metabolism of myeloid cells. Toll-like receptor (TLR) stimulation shifts intracellular…”
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Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription by Paiva, Isabel, Cellai, Lucrezia, Meriaux, Céline, Poncelet, Lauranne, Nebie, Ouada, Saliou, Jean-Michel, Lacoste, Anne-Sophie, Papegaey, Anthony, Drobecq, Hervé, Le Gras, Stéphanie, Schneider, Marion, Malik, Enas M., Müller, Christa E., Faivre, Emilie, Carvalho, Kevin, Gomez-Murcia, Victoria, Vieau, Didier, Thiroux, Bryan, Eddarkaoui, Sabiha, Lebouvier, Thibaud, Schueller, Estelle, Tzeplaeff, Laura, Grgurina, Iris, Seguin, Jonathan, Stauber, Jonathan, Lopes, Luisa, Buée, Luc, Buée-Scherrer, Valérie, Cunha, Rodrigo, Ait-Belkacem, Rima, Sergeant, Nicolas, Annicotte, Jean-Sébastien, Boutillier, Anne-Laurence, Blum, David

“…Copyright © 2022, Paiva et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License. Caffeine…”
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Leptin brain entry via a tanycytic LepR–EGFR shuttle controls lipid metabolism and pancreas function by Duquenne, Manon, Folgueira, Cintia, Bourouh, Cyril, Millet, Marion, Silva, Anisia, Clasadonte, Jérôme, Imbernon, Monica, Fernandois, Daniela, Martinez-Corral, Ines, Kusumakshi, Soumya, Caron, Emilie, Rasika, S., Deliglia, Eleonora, Jouy, Nathalie, Oishi, Asturo, Mazzone, Massimiliano, Trinquet, Eric, Tavernier, Jan, Kim, Young-Bum, Ory, Stéphane, Jockers, Ralf, Schwaninger, Markus, Boehm, Ulrich, Nogueiras, Ruben, Annicotte, Jean-Sébastien, Gasman, Stéphane, Dam, Julie, Prévot, Vincent

“…Metabolic health depends on the brain’s ability to control food intake and nutrient use versus storage, processes that require peripheral signals such as the…”
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CDK4 is an essential insulin effector in adipocytes by Lagarrigue, Sylviane, Lopez-Mejia, Isabel C, Denechaud, Pierre-Damien, Escoté, Xavier, Castillo-Armengol, Judit, Jimenez, Veronica, Chavey, Carine, Giralt, Albert, Lai, Qiuwen, Zhang, Lianjun, Martinez-Carreres, Laia, Delacuisine, Brigitte, Annicotte, Jean-Sébastien, Blanchet, Emilie, Huré, Sébastien, Abella, Anna, Tinahones, Francisco J, Vendrell, Joan, Dubus, Pierre, Bosch, Fatima, Kahn, C Ronald, Fajas, Lluis

“…Insulin resistance is a fundamental pathogenic factor that characterizes various metabolic disorders, including obesity and type 2 diabetes. Adipose tissue…”
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β-Cell-Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion by Oger, Frédérik, Bourouh, Cyril, Friano, Marika Elsa, Courty, Emilie, Rolland, Laure, Gromada, Xavier, Moreno, Maeva, Carney, Charlène, Rabhi, Nabil, Durand, Emmanuelle, Amanzougarene, Souhila, Berberian, Lionel, Derhourhi, Mehdi, Blanc, Etienne, Hannou, Sarah Anissa, Denechaud, Pierre-Damien, Benfodda, Zohra, Meffre, Patrick, Fajas, Lluis, Kerr-Conte, Julie, Pattou, François, Froguel, Philippe, Pourcet, Benoit, Bonnefond, Amélie, Collombat, Patrick, Annicotte, Jean-Sébastien

“…The loss of pancreatic β-cell identity has emerged as an important feature of type 2 diabetes development, but the molecular mechanisms are still elusive…”
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Compromised Intestinal Lipid Absorption in Mice with a Liver-Specific Deficiency of Liver Receptor Homolog 1 by Mataki, Chikage, Magnier, Benjamin C., Houten, Sander M., Annicotte, Jean-Sébastien, Argmann, Carmen, Thomas, Charles, Overmars, Henk, Kulik, Wim, Metzger, Daniel, Auwerx, Johan, Schoonjans, Kristina

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Improved synthesis, resolution, absolute configuration determination and biological evaluation of HLM006474 enantiomers by Rosales-Hurtado, Miyanou, Lebeau, Alexandre, Bourouh, Cyril, Cebrian-Torrejon, Gerardo, Albalat, Muriel, Jean, Marion, Naubron, Jean-Valère, Annicotte, Jean-Sébastien, Benfodda, Zohra, Meffre, Patrick

“…[Display omitted] An improved green synthesis of the E2F inhibitor HLM0066474 is described, using solvent-free and microwave irradiation conditions. The two…”
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The CDK4–pRB–E2F1 pathway controls insulin secretion by Annicotte, Jean-Sébastien, Blanchet, Emilie, Chavey, Carine, Iankova, Irena, Costes, Safia, Assou, Said, Teyssier, Jacques, Dalle, Stéphane, Sardet, Claude, Fajas, Lluis

“…The Cdk4–pRb–E2F1 pathway is shown to have a role in insulin secretion in b cells by controlling the expression of a subunit of the K+ATP channel through E2F1…”
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The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells by Bourouh, Cyril, Courty, Emilie, Rolland, Laure, Pasquetti, Gianni, Gromada, Xavier, Rabhi, Nabil, Carney, Charlène, Moreno, Maeva, Boutry, Raphaël, Caron, Emilie, Benfodda, Zohra, Meffre, Patrick, Kerr-Conte, Julie, Pattou, François, Froguel, Philippe, Bonnefond, Amélie, Oger, Frédérik, Annicotte, Jean-Sébastien

“…The glucagon-like peptide 1 (Glp-1) has emerged as a hormone with broad pharmacological potential in type 2 diabetes (T2D) treatment, notably by improving β…”
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Lamin C Counteracts Glucose Intolerance in Aging, Obesity, and Diabetes Through β-Cell Adaptation by de Toledo, Marion, Lopez-Mejia, Isabel C, Cavelier, Patricia, Pratlong, Marine, Barrachina, Célia, Gromada, Xavier, Annicotte, Jean-Sébastien, Tazi, Jamal, Chavey, Carine

“…Aging-dependent changes in tissue function are associated with the development of metabolic diseases. However, the molecular connections linking aging,…”
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PPARγ contributes to PKM2 and HK2 expression in fatty liver by Panasyuk, Ganna, Espeillac, Catherine, Chauvin, Céline, Pradelli, Ludivine A., Horie, Yasuo, Suzuki, Akira, Annicotte, Jean-Sebastien, Fajas, Lluis, Foretz, Marc, Verdeguer, Francisco, Pontoglio, Marco, Ferré, Pascal, Scoazec, Jean-Yves, Birnbaum, Morris J., Ricci, Jean-Ehrland, Pende, Mario

“…Rapidly proliferating cells promote glycolysis in aerobic conditions, to increase growth rate. Expression of specific glycolytic enzymes, namely pyruvate…”
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Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System by Deckmyn, Benjamin, Domenger, Dorothée, Blondel, Chloé, Ducastel, Sarah, Nicolas, Emilie, Dorchies, Emilie, Caron, Emilie, Charton, Julie, Vallez, Emmanuelle, Deprez, Benoit, Annicotte, Jean-Sébastien, Lestavel, Sophie, Tailleux, Anne, Magnan, Christophe, Staels, Bart, Bantubungi, Kadiombo

“…The nuclear bile acid (BA) receptor farnesoid X receptor (FXR) is a major regulator of metabolic/energy homeostasis in peripheral organs. Indeed,…”
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Cyclin G2 Regulates Adipogenesis through PPARγ Coactivation by Aguilar, Victor, Annicotte, Jean-Sébastien, Escote, Xavier, Vendrell, Joan, Langin, Dominique, Fajas, Lluis

“…Cell cycle regulators such as cyclins, cyclin-dependent kinases, or retinoblastoma protein play important roles in the differentiation of adipocytes. In the…”
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Cardiac Acetylation in Metabolic Diseases by Dubois-Deruy, Emilie, El Masri, Yara, Turkieh, Annie, Amouyel, Philippe, Pinet, Florence, Annicotte, Jean-Sébastien

“…Lysine acetylation is a highly conserved mechanism that affects several biological processes such as cell growth, metabolism, enzymatic activity, subcellular…”
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Cofactors As Metabolic Sensors Driving Cell Adaptation in Physiology and Disease by Rabhi, Nabil, Hannou, Sarah Anissa, Froguel, Philippe, Annicotte, Jean-Sébastien

“…Chromatin architectures and epigenetic fingerprint regulation are fundamental for genetically determined biological processes. Chemical modifications of the…”
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LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease by Coste, Agnes, Dubuquoy, Laurent, Barnouin, Romain, Annicotte, Jean-Sebastien, Magnier, Benjamin, Notti, Mario, Corazza, Nadia, Antal, Maria Cristina, Metzger, Daniel, Desreumaux, Pierre, Brunner, Thomas, Auwerx, Johan, Schoonjans, Kristina

“…Liver receptor homolog-1 (LRH-1) is a nuclear receptor involved in intestinal lipid homeostasis and cell proliferation. Here we show that haploinsufficiency of…”
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Emerging Roles for the INK4a/ARF ( CDKN2A ) Locus in Adipose Tissue: Implications for Obesity and Type 2 Diabetes by Kahoul, Yasmina, Oger, Frédérik, Montaigne, Jessica, Froguel, Philippe, Breton, Christophe, Annicotte, Jean-Sébastien

“…Besides its role as a cell cycle and proliferation regulator, the ( ) locus and its associated pathways are thought to play additional functions in the control…”
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