Search Results - "Anne Schaefer"

General principals of miRNA biogenesis and regulation in the brain by O'Carroll, Dónal, Schaefer, Anne

“…MicroRNAs (miRNAs) are small, noncoding RNAs that mediate posttranscriptional gene suppression in a sequence-specific manner. The ability of a single miRNA…”
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Innate sensing of mechanical properties of brain tissue by microglia by Ayata, Pinar, Schaefer, Anne

“…•Microglia display diverse and brain region-specific phenotypes.•Microglial response to protein aggregates/plaques during Alzheimer disease resembles…”
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The knowledge gap on the ECMO gap: The importance of speaking the same language by Mariani, Silvia, Makhoul, Maged, Schaefer, Anne-Kristin, Wiedemann, Dominik, Lorusso, Roberto

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An AUTS2–Polycomb complex activates gene expression in the CNS by Gao, Zhonghua, Lee, Pedro, Stafford, James M., von Schimmelmann, Melanie, Schaefer, Anne, Reinberg, Danny

“…Naturally occurring variations of Polycomb repressive complex 1 (PRC1) comprise a core assembly of Polycomb group proteins and additional factors that include,…”
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Negative feedback control of neuronal activity by microglia by Badimon, Ana, Strasburger, Hayley J., Ayata, Pinar, Chen, Xinhong, Nair, Aditya, Ikegami, Ako, Hwang, Philip, Chan, Andrew T., Graves, Steven M., Uweru, Joseph O., Ledderose, Carola, Kutlu, Munir Gunes, Wheeler, Michael A., Kahan, Anat, Ishikawa, Masago, Wang, Ying-Chih, Loh, Yong-Hwee E., Jiang, Jean X., Surmeier, D. James, Robson, Simon C., Junger, Wolfgang G., Sebra, Robert, Calipari, Erin S., Kenny, Paul J., Eyo, Ukpong B., Colonna, Marco, Quintana, Francisco J., Wake, Hiroaki, Gradinaru, Viviana, Schaefer, Anne

“…Microglia, the brain’s resident macrophages, help to regulate brain function by removing dying neurons, pruning non-functional synapses, and producing ligands…”
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Epigenetic regulation of brain region-specific microglia clearance activity by Ayata, Pinar, Badimon, Ana, Strasburger, Hayley J., Duff, Mary Kaye, Montgomery, Sarah E., Loh, Yong-Hwee E., Ebert, Anja, Pimenova, Anna A., Ramirez, Brianna R., Chan, Andrew T., Sullivan, Josefa M., Purushothaman, Immanuel, Scarpa, Joseph R., Goate, Alison M., Busslinger, Meinrad, Shen, Li, Losic, Bojan, Schaefer, Anne

“…The rapid elimination of dying neurons and nonfunctional synapses in the brain is carried out by microglia, the resident myeloid cells of the brain. Here we…”
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The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System by Cholewa-Waclaw, Justyna, Bird, Adrian, von Schimmelmann, Melanie, Schaefer, Anne, Yu, Huimei, Song, Hongjun, Madabhushi, Ram, Tsai, Li-Huei

“…Neuroepigenetics is a newly emerging field in neurobiology that addresses the epigenetic mechanism of gene expression regulation in various postmitotic…”
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Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling by Gunner, Georgia, Cheadle, Lucas, Johnson, Kasey M., Ayata, Pinar, Badimon, Ana, Mondo, Erica, Nagy, M. Aurel, Liu, Liwang, Bemiller, Shane M., Kim, Ki-Wook, Lira, Sergio A., Lamb, Bruce T., Tapper, Andrew R., Ransohoff, Richard M., Greenberg, Michael E., Schaefer, Anne, Schafer, Dorothy P.

“…Microglia rapidly respond to changes in neural activity and inflammation to regulate synaptic connectivity. The extracellular signals, particularly…”
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CSF-1 controls cerebellar microglia and is required for motor function and social interaction by Kana, Veronika, Desland, Fiona A, Casanova-Acebes, Maria, Ayata, Pinar, Badimon, Ana, Nabel, Elisa, Yamamuro, Kazuhiko, Sneeboer, Marjolein, Tan, I-Li, Flanigan, Meghan E, Rose, Samuel A, Chang, Christie, Leader, Andrew, Le Bourhis, Hortense, Sweet, Eric S, Tung, Navpreet, Wroblewska, Aleksandra, Lavin, Yonit, See, Peter, Baccarini, Alessia, Ginhoux, Florent, Chitu, Violeta, Stanley, E Richard, Russo, Scott J, Yue, Zhenyu, Brown, Brian D, Joyner, Alexandra L, De Witte, Lotje D, Morishita, Hirofumi, Schaefer, Anne, Merad, Miriam

“…Microglia, the brain resident macrophages, critically shape forebrain neuronal circuits. However, their precise function in the cerebellum is unknown. Here we…”
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Preoperative anatomical landmarks and longitudinal HeartMate 3 pump position in X‐rays: Relevance for adverse events by Widhalm, Gregor, Aigner, Philipp, Gruber, Bernhard, Moscato, Francesco, Moayedifar, Roxana, Schaefer, Anne‐Kristin, Dimitrov, Kamen, Zimpfer, Daniel, Riebandt, Julia, Schlöglhofer, Thomas

“…Background Left ventricular assist device (LVAD) malposition has been linked to hemocompatibility‐related adverse events (HRAEs). This study aimed to identify…”
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Access site complications of postcardiotomy extracorporeal life support by Schaefer, Anne-Kristin, Distelmaier, Klaus, Riebandt, Julia, Goliasch, Georg, Bernardi, Martin H., Zimpfer, Daniel, Laufer, Günther, Wiedemann, Dominik

“…To assess the influence of primary arterial access in patients receiving peripheral postcardiotomy extracorporeal life support on associated complications and…”
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Convergence of spectrums: neuronal gene network states in autism spectrum disorder by Sullivan, Josefa M, De Rubeis, Silvia, Schaefer, Anne

“…Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized by social deficits and restrictive and/or repetitive behaviors. The…”
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Bleeding and thrombotic events in post-cardiotomy extracorporeal life support by Schaefer, Anne-Kristin, Latus, Michaela, Riebandt, Julia, Goliasch, Georg, Bernardi, Martin H, Laufer, Günther, Zimpfer, Daniel, Wiedemann, Dominik

“…Abstract OBJECTIVES Haemorrhagic and thrombotic complications are known obstacles in extracorporeal life support (ECLS), and patients requiring post-cardiotomy…”
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Ecological divergence of wild birds drives avian influenza spillover and global spread by Hill, Nichola J, Bishop, Mary Anne, Trovão, Nídia S, Ineson, Katherine M, Schaefer, Anne L, Puryear, Wendy B, Zhou, Katherine, Foss, Alexa D, Clark, Daniel E, MacKenzie, Kenneth G, Gass, Jr, Jonathon D, Borkenhagen, Laura K, Hall, Jeffrey S, Runstadler, Jonathan A

“…The diversity of influenza A viruses (IAV) is primarily hosted by two highly divergent avian orders: Anseriformes (ducks, swans and geese) and Charadriiformes…”
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Heatwave‐induced synchrony within forage fish portfolio disrupts energy flow to top pelagic predators by Arimitsu, Mayumi L., Piatt, John F., Hatch, Scott, Suryan, Robert M., Batten, Sonia, Bishop, Mary Anne, Campbell, Rob W., Coletti, Heather, Cushing, Dan, Gorman, Kristen, Hopcroft, Russell R., Kuletz, Kathy J., Marsteller, Caitlin, McKinstry, Caitlin, McGowan, David, Moran, John, Pegau, Scott, Schaefer, Anne, Schoen, Sarah, Straley, Jan, Biela, Vanessa R.

“…During the Pacific marine heatwave of 2014–2016, abundance and quality of several key forage fish species in the Gulf of Alaska were simultaneously reduced…”
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Fate of patients weaned from post-cardiotomy extracorporeal life support by Schaefer, Anne-Kristin, Riebandt, Julia, Bernardi, Martin H, Distelmaier, Klaus, Goliasch, Georg, Zimpfer, Daniel, Laufer, Günther, Wiedemann, Dominik

“…Abstract OBJECTIVES Although post-cardiotomy extracorporeal life support (PC-ECLS) is a potentially life-saving resource for patients with cardiopulmonary…”
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MicroRNA-128 Governs Neuronal Excitability and Motor Behavior in Mice by Tan, Chan Lek, Plotkin, Joshua L., Venø, Morten T., von Schimmelmann, Melanie, Feinberg, Philip, Mann, Silas, Handler, Annie, Kjems, Jørgen, Surmeier, D. James, O'Carroll, Dónal, Greengard, Paul, Schaefer, Anne

“…The control of motor behavior in animals and humans requires constant adaptation of neuronal networks to signals of various types and strengths. We found that…”
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Cerebellar neurodegeneration in the absence of microRNAs by Schaefer, Anne, O'Carroll, Dónal, Tan, Chan Lek, Hillman, Dean, Sugimori, Mutsuyuki, Llinas, Rodolfo, Greengard, Paul

“…Genome-encoded microRNAs (miRNAs) are potent regulators of gene expression. The significance of miRNAs in various biological processes has been suggested by…”
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Anticoagulation strategy in a patient on the HeartMate III® left ventricular assist device with acquired von Willebrand syndrome and recurring gastrointestinal bleeding episodes: sometimes less is more by Grabner, Bernhard, Quehenberger, Peter, Schaefer, Anne-Kristin, Steinlechner, Barbara

“…Abstract Acquired von Willebrand syndrome is a frequently encountered complication of continuous flow ventricular assist devices, which may lead to clinically…”
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A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types by Heiman, Myriam, Schaefer, Anne, Gong, Shiaoching, Peterson, Jayms D., Day, Michelle, Ramsey, Keri E., Suárez-Fariñas, Mayte, Schwarz, Cordelia, Stephan, Dietrich A., Surmeier, D. James, Greengard, Paul, Heintz, Nathaniel

“…The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations. Using bacterial artificial…”
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