Search Results - "Annavarapu, Vidya"
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Current State of Oligonucleotide Characterization Using Liquid Chromatography–Mass Spectrometry: Insight into Critical Issues
Published in Journal of the American Society for Mass Spectrometry (02-09-2020)“…As interests increase in oligonucleotide therapeutics, there has been a greater need for analytical techniques to properly analyze and quantitate these…”
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Journal Article -
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Mobile Phase Aging and Its Impact on Electrospray Ionization of Oligonucleotides
Published in Journal of the American Society for Mass Spectrometry (06-12-2023)“…The implementation of fluoroalcohol/alkylamine mobile phase systems in oligonucleotide LC-MS provides a good balance between chromatographic separations and MS…”
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Journal Article -
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Chromatographic Analysis of Oligonucleotide Sequences Using pH Adjusted TEA/HFIP Buffer System
Published 01-01-2020“…Oligonucleotides are short nucleic acid polymers used in research, genetic testing and forensics. When used for these applications, they are generally made up…”
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Dissertation -
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Prodrug Strategies for the Development of β‑l‑5-((E)‑2-Bromovinyl)-1-((2S,4S)‑2-(hydroxymethyl)-1,3-(dioxolane-4-yl))uracil (l‑BHDU) against Varicella Zoster Virus (VZV)
Published in Journal of medicinal chemistry (25-05-2023)“…Varicella zoster virus (VZV) establishes lifelong infection after primary disease and can reactivate. Several drugs are approved to treat VZV diseases, but new…”
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Journal Article