Search Results - "Annals of neurology"

Disease‐Modifying Therapies and Coronavirus Disease 2019 Severity in Multiple Sclerosis by Sormani, Maria P., Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Moiola, Lucia, Zaratin, Paola, Tedeschi, Gioacchino, Patti, Francesco, Di Sapio, Alessia, Signori, Alessio, Iovino, Aniello, Repice, Anna Maria, Gallo, Antonio, Zito, Antonio, Pozzilli, Carlo, Mancinelli, Chiara Rosa, Zanetta, Chiara, Cordano, Christian, Guaschino, Clara, Gasperini, Claudio, Bezzini, Daiana, Marastoni, Damiano, Paolicelli, Damiano, Bucciantini, Elisabetta, Sbragia, Elvira, Susani, Emanuela Laura, Curti, Erica, Marinelli, Fabiana, Govone, Flora, Calabria, Francesca, Caleri, Francesca, Rinaldi, Francesca, Corea, Francesco, Patti, Francesco, Teatini, Francesco, Tabiadon, Giulietta, Granella, Franco, Lus, Giacomo, Brichetto, Giampaolo, Comi, Giancarlo, Tedeschi, Gioacchino, Borriello, Giovanna, Konrad, Giovanna, Mallucci, Giulia, Salemi, Giuseppe, Pesci, Ilaria, Lopiano, Leonardo, Pasquali, Livia, Carmisciano, Luca, Chiveri, Luca, Mancinelli, Luca, Caniatti, Luisa Maria, Cava, Marco Della, Salvetti, Marco, Vercellino, Marco, Bragadin, Margherita Monti, Celani, Maria Grazia, Stromillo, Maria Laura, Petracca, Maria, Amato, Maria Pia, Sormani, Maria Pia, L'Episcopo, Maria Rita, Ercolani, Maria Vittoria, Bianco, Mariangela, Clerico, Marinella, Ponzano, Marta, Radaelli, Marta, Conti, Marta Zaffira, Mirabella, Massimiliano, Filippi, Massimo, Inglese, Matilde, Danni, Maura Chiara, Zaffaroni, Mauro, Ponzio, Michela, Cavalla, Paola, De Mitri, Paola, Confalonieri, Paolo, Gallo, Paolo, Ragonese, Paolo, Clerici, Raffaella, Lanzillo, Roberta, Motta, Roberta, Balgera, Roberto, Bergamaschi, Roberto, Totaro, Rocco, Iodice, Rosa, Capra, Ruggero, Marangoni, Sabrina, Realmuto, Sabrina, Cottone, Salvatore, Banfi, Silvia, Malucchi, Simona, Tonietti, Simone, Vollaro, Stefano, Cordera, Susanna, Aguglia, Umberto, Barcella, Valeria, Morra, Vincenzo Brescia, Dattola, Vincenzo, Mantero, Vittorio

“…Objective This study was undertaken to assess the impact of immunosuppressive and immunomodulatory therapies on the severity of coronavirus disease 2019…”
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COVID‐19: A Global Threat to the Nervous System by Koralnik, Igor J., Tyler, Kenneth L.

“…In less than 6 months, the severe acute respiratory syndrome‐coronavirus type 2 (SARS‐CoV‐2) has spread worldwide infecting nearly 6 million people and killing…”
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Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis by Disanto, Giulio, Barro, Christian, Benkert, Pascal, Naegelin, Yvonne, Schädelin, Sabine, Giardiello, Antonella, Zecca, Chiara, Blennow, Kaj, Zetterberg, Henrik, Leppert, David, Kappos, Ludwig, Gobbi, Claudio, Kuhle, Jens, Kuhle, Jens, Lorscheider, Johannes, Yaldizli, Özgür, Derfuss, Tobias, Kappos, Ludwig, Disanto, Giulio, Zecca, Chiara, Gobbi, Claudio, Benkert, Pascal, Achtnichts, Lutz, Nedeltchev, Krassen, Kamm, Christian P, Salmen, Anke, Chan, Andrew, Lalive, Patrice H, Pot, Caroline, Schluep, Myriam, Granziera, Cristina, Du Pasquier, Renaud, Müller, Stefanie, Vehoff, Jochen

“…Objective Neurofilament light chains (NfL) are unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectable at low concentrations in…”
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Autoimmune encephalitis epidemiology and a comparison to infectious encephalitis by Dubey, Divyanshu, Pittock, Sean J., Kelly, Cecilia R., McKeon, Andrew, Lopez‐Chiriboga, Alfonso Sebastian, Lennon, Vanda A., Gadoth, Avi, Smith, Carin Y., Bryant, Sandra C., Klein, Christopher J., Aksamit, Allen J., Toledano, Michel, Boeve, Bradley F., Tillema, Jan-Mendelt, Flanagan, Eoin P.

“…Objective To evaluate the incidence and prevalence of autoimmune encephalitis and compare it to that of infectious encephalitis. Methods We performed a…”
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Silent progression in disease activity–free relapsing multiple sclerosis by Cree, Bruce A. C., Hollenbach, Jill A., Bove, Riley, Kirkish, Gina, Sacco, Simone, Caverzasi, Eduardo, Bischof, Antje, Gundel, Tristan, Zhu, Alyssa H., Papinutto, Nico, Stern, William A., Bevan, Carolyn, Romeo, Andrew, Goodin, Douglas S., Gelfand, Jeffrey M., Graves, Jennifer, Green, Ari J., Wilson, Michael R., Zamvil, Scott S., Zhao, Chao, Gomez, Refujia, Ragan, Nicholas R., Rush, Gillian Q., Barba, Patrick, Santaniello, Adam, Baranzini, Sergio E., Oksenberg, Jorge R., Henry, Roland G., Hauser, Stephen L.

“…Objective Rates of worsening and evolution to secondary progressive multiple sclerosis (MS) may be substantially lower in actively treated patients compared to…”
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Steroid‐Responsive Encephalitis in Coronavirus Disease 2019 by Pilotto, Andrea, Odolini, Silvia, Masciocchi, Stefano, Comelli, Agnese, Volonghi, Irene, Gazzina, Stefano, Nocivelli, Sara, Pezzini, Alessandro, Focà, Emanuele, Caruso, Arnaldo, Leonardi, Matilde, Pasolini, Maria P., Gasparotti, Roberto, Castelli, Francesco, Ashton, Nicholas J., Blennow, Kaj, Zetterberg, Henrik, Padovani, Alessandro

“…Coronavirus disease 2019 (COVID‐19) infection has the potential for targeting the central nervous system, and several neurological symptoms have been described…”
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Chemotherapy‐induced peripheral neuropathy: A current review by Staff, Nathan P., Grisold, Anna, Grisold, Wolfgang, Windebank, Anthony J.

“…Chemotherapy‐induced peripheral neuropathy (CIPN) is a common dose‐limiting side effect experienced by patients receiving treatment for cancer. Approximately…”
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Connectivity Predicts deep brain stimulation outcome in Parkinson disease by Horn, Andreas, Reich, Martin, Vorwerk, Johannes, Li, Ningfei, Wenzel, Gregor, Fang, Qianqian, Schmitz‐Hübsch, Tanja, Nickl, Robert, Kupsch, Andreas, Volkmann, Jens, Kühn, Andrea A., Fox, Michael D.

“…Objective The benefit of deep brain stimulation (DBS) for Parkinson disease (PD) may depend on connectivity between the stimulation site and other brain…”
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Tau positron emission tomographic imaging in aging and early Alzheimer disease by Johnson, Keith A., Schultz, Aaron, Betensky, Rebecca A., Becker, J. Alex, Sepulcre, Jorge, Rentz, Dorene, Mormino, Elizabeth, Chhatwal, Jasmeer, Amariglio, Rebecca, Papp, Kate, Marshall, Gad, Albers, Mark, Mauro, Samantha, Pepin, Lesley, Alverio, Jonathan, Judge, Kelly, Philiossaint, Marlie, Shoup, Timothy, Yokell, Daniel, Dickerson, Bradford, Gomez-Isla, Teresa, Hyman, Bradley, Vasdev, Neil, Sperling, Reisa

“…Objective Detection of focal brain tau deposition during life could greatly facilitate accurate diagnosis of Alzheimer disease (AD), staging and monitoring of…”
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Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the EPISTOP Trial by Kotulska, Katarzyna, Kwiatkowski, David J., Curatolo, Paolo, Weschke, Bernhard, Riney, Kate, Jansen, Floor, Feucht, Martha, Krsek, Pavel, Nabbout, Rima, Jansen, Anna C., Wojdan, Konrad, Sijko, Kamil, Głowacka‐Walas, Jagoda, Borkowska, Julita, Sadowski, Krzysztof, Domańska‐Pakieła, Dorota, Moavero, Romina, Hertzberg, Christoph, Hulshof, Hanna, Scholl, Theresa, Benova, Barbora, Aronica, Eleonora, Ridder, Jessie, Lagae, Lieven, Jóźwiak, Sergiusz, Anink, J., Aronica, E., Benova, B., Benvenuto, A., Blazejczyk, M., Bongaerts, A., Borkowska, J., Breuillard, D., Chmielewski, D., Curatolo, P., Dabrowska, M., Domańska‐Pakieła, D., Feucht, M., Giannikou, K., Głowacka‐Walas, J., Hamieh, L., Harȩza, A., Hertzberg, Ch, Hulshof, H., Huschner, F., Iyer, A., Jansen, A., Jansen, F., Janssen, B., Jaworski, J., Jùźwiak, S., Kaczorowska‐Frontczak, M., Kotulska, K., Krsek, P., Kwiatkowski, D., Lagae, L., Lehmann, K., Leusman, A., Maćkowiak, N., Mills, J., Moavero, R., Muelebner, A., Nabbout, R., Ridder, J., Riney, K., Sadowski, K., Samueli, S., Scheldeman, C., Scholl, T., Sciuto, A., Sijko, K., Słowińska, M., Tempes, A., Scheppingen, J., Verhelle, B., Vervisch, J., Urbańska, M., Weschke, B., Wojdan, K.

“…Objective Epilepsy develops in 70 to 90% of children with tuberous sclerosis complex (TSC) and is often resistant to medication. Recently, the concept of…”
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Neutrophil extracellular traps in ischemic stroke thrombi by Laridan, Elodie, Denorme, Frederik, Desender, Linda, François, Olivier, Andersson, Tommy, Deckmyn, Hans, Vanhoorelbeke, Karen, Meyer, Simon F.

“…Objective Neutrophil extracellular traps (NETs) have been shown to promote thrombus formation. Little is known about the exact composition of thrombi that…”
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Age‐related changes in the gut microbiota influence systemic inflammation and stroke outcome by Spychala, Monica S., Venna, Venugopal Reddy, Jandzinski, Michal, Doran, Sarah J., Durgan, David J., Ganesh, Bhanu Priya, Ajami, Nadim J., Putluri, Nagireddy, Graf, Joerg, Bryan, Robert M., McCullough, Louise D.

“…Objective Chronic systemic inflammation contributes to the pathogenesis of many age‐related diseases. Although not well understood, alterations in the gut…”
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Deep gray matter volume loss drives disability worsening in multiple sclerosis by Eshaghi, Arman, Prados, Ferran, Brownlee, Wallace J., Altmann, Daniel R., Tur, Carmen, Cardoso, M. Jorge, De Angelis, Floriana, van de Pavert, Steven H., Cawley, Niamh, De Stefano, Nicola, Stromillo, M. Laura, Battaglini, Marco, Ruggieri, Serena, Gasperini, Claudio, Filippi, Massimo, Rocca, Maria A., Rovira, Alex, Sastre‐Garriga, Jaume, Vrenken, Hugo, Leurs, Cyra E., Killestein, Joep, Pirpamer, Lukas, Enzinger, Christian, Ourselin, Sebastien, Wheeler‐Kingshott, Claudia A.M. Gandini, Chard, Declan, Thompson, Alan J., Alexander, Daniel C., Barkhof, Frederik, Ciccarelli, Olga

“…Objective Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We investigated whether there is a spatiotemporal pattern of GM atrophy…”
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Guillain‐Barré Syndrome following ChAdOx1‐S/nCoV‐19 Vaccine by Maramattom, Boby V., Krishnan, Parameswaran, Paul, Reji, Padmanabhan, Sandeep, Cherukudal Vishnu Nampoothiri, Soumya, Syed, Akheel A., Mangat, Halinder S.

“…As of April 22, 2021, around 1.5 million individuals in three districts of Kerala, India had been vaccinated with COVID‐19 vaccines. Over 80% of these…”
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Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: Analysis of 102 patients by Flanagan, Eoin P., Hinson, Shannon R., Lennon, Vanda A., Fang, Boyan, Aksamit, Allen J., Morris, P. Pearse, Basal, Eati, Honorat, Josephe A., Alfugham, Nora B., Linnoila, Jenny J., Weinshenker, Brian G., Pittock, Sean J., McKeon, Andrew

“…Objective A novel autoimmune central nervous system (CNS) disorder with glial fibrillary acidic protein (GFAP)‐IgG as biomarker was recently characterized…”
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Person‐specific contribution of neuropathologies to cognitive loss in old age by Boyle, Patricia A., Yu, Lei, Wilson, Robert S., Leurgans, Sue E., Schneider, Julie A., Bennett, David A.

“…Objective Mixed neuropathologies are the most common cause of dementia at the population level, but how different neuropathologies contribute to cognitive…”
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Impairment of the Glymphatic Pathway and Putative Meningeal Lymphatic Vessels in the Aging Human by Zhou, Ying, Cai, Jinsong, Zhang, Wenhua, Gong, Xiaoxian, Yan, Shenqiang, Zhang, Kemeng, Luo, Zhongyu, Sun, Jianzhong, Jiang, Quan, Lou, Min

“…Objective Aging is a major risk factor for numerous neurological disorders, and the mechanisms underlying brain aging remain elusive. Recent animal studies…”
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Guillain–Barré Syndrome Variant Occurring after SARS‐CoV‐2 Vaccination by Allen, Christopher Martin, Ramsamy, Shelby, Tarr, Alexander William, Tighe, Patrick Jason, Irving, William Lucien, Tanasescu, Radu, Evans, Jonathan Rhys

“…Although SARS‐CoV‐2 vaccines are very safe, we report 4 cases of the bifacial weakness with paresthesias variant of Guillain–Barré syndrome (GBS) occurring…”
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Safety and Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study) by Lynch, David R., Chin, Melanie P., Delatycki, Martin B., Subramony, S. H., Corti, Manuela, Hoyle, J. Chad, Boesch, Sylvia, Nachbauer, Wolfgang, Mariotti, Caterina, Mathews, Katherine D., Giunti, Paola, Wilmot, George, Zesiewicz, Theresa, Perlman, Susan, Goldsberry, Angie, O'Grady, Megan, Meyer, Colin J.

“…Objective Friedreich ataxia (FA) is a progressive genetic neurodegenerative disorder with no approved treatment. Omaveloxolone, an Nrf2 activator, improves…”
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Impairment of paravascular clearance pathways in the aging brain by Kress, Benjamin T., Iliff, Jeffrey J., Xia, Maosheng, Wang, Minghuan, Wei, Helen S., Zeppenfeld, Douglas, Xie, Lulu, Kang, Hongyi, Xu, Qiwu, Liew, Jason A., Plog, Benjamin A., Ding, Fengfei, Deane, Rashid, Nedergaard, Maiken

“…Objective In the brain, protein waste removal is partly performed by paravascular pathways that facilitate convective exchange of water and soluble contents…”
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