Search Results - "Annala, M."

Fusion genes and their discovery using high throughput sequencing by Annala, M.J, Parker, B.C, Zhang, W, Nykter, M

“…Abstract Fusion genes are hybrid genes that combine parts of two or more original genes. They can form as a result of chromosomal rearrangements or abnormal…”
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An ancestral molecular response to nanomaterial particulates by del Giudice, G., Serra, A., Saarimäki, L. A., Kotsis, K., Rouse, I., Colibaba, S. A., Jagiello, K., Mikolajczyk, A., Fratello, M., Papadiamantis, A. G., Sanabria, N., Annala, M. E., Morikka, J., Kinaret, P. A. S., Voyiatzis, E., Melagraki, G., Afantitis, A., Tämm, K., Puzyn, T., Gulumian, M., Lobaskin, V., Lynch, I., Federico, A., Greco, D.

“…The varied transcriptomic response to nanoparticles has hampered the understanding of the mechanism of action. Here, by performing a meta-analysis of a large…”
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Cabazitaxel versus abiraterone or enzalutamide in poor prognosis metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase II trial by Annala, M., Fu, S., Bacon, J.V.W., Sipola, J., Iqbal, N., Ferrario, C., Ong, M., Wadhwa, D., Hotte, S.J., Lo, G., Tran, B., Wood, L.A., Gingerich, J.R., North, S.A., Pezaro, C.J., Ruether, J.D., Sridhar, S.S., Kallio, H.M.L., Khalaf, D.J., Wong, A., Beja, K., Schönlau, E., Taavitsainen, S., Nykter, M., Vandekerkhove, G., Azad, A.A., Wyatt, A.W., Chi, K.N.

“…Treatment of poor prognosis metastatic castration-resistant prostate cancer (mCRPC) includes taxane chemotherapy and androgen receptor pathway inhibitors…”
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Multi-stressor impacts on fungal diversity and ecosystem functions in streams: natural vs. anthropogenic stress by Tolkkinen, M, Mykrä, H, Annala, M, Markkola, A. M, Vuori, K. M, Muotka, T

“…Biological assemblages are often subjected to multiple stressors emerging from both anthropogenic activities and naturally stressful conditions, and species'…”
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In situ polymerized nanocomposites: Polystyrene/CNT and Poly(methyl methacrylate)/CNT composites by Lahelin, M., Annala, M., Nykänen, A., Ruokolainen, J., Seppälä, J.

“…Carbon nanotubes (CNTs) were incorporated into polystyrene (PS) and poly(methyl methacrylate) (PMMA) matrices via in situ emulsion and emulsion/suspension…”
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IGFBP2 potentiates nuclear EGFR–STAT3 signaling by Chua, C Y, Liu, Y, Granberg, K J, Hu, L, Haapasalo, H, Annala, M J, Cogdell, D E, Verploegen, M, Moore, L M, Fuller, G N, Nykter, M, Cavenee, W K, Zhang, W

“…Insulin-like growth factor binding protein 2 (IGFBP2) is a pleiotropic oncogenic protein that has both extracellular and intracellular functions. Despite a…”
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HSD3B1 (1245A>C) germline variant and clinical outcomes in metastatic castration-resistant prostate cancer patients treated with abiraterone and enzalutamide: results from two prospective studies by Khalaf, D.J., Aragón, I.M., Annala, M., Lozano, R., Taavitsainen, S., Lorente, D., Finch, D.L., Romero-Laorden, N., Vergidis, J., Cendón, Y., Oja, C., Pacheco, M.I., Zulfiqar, M., Almagro, E., Arranz, J.Á., Billalabeitia, E.G., Borrega, P., Castro, E., Contreras, J.A., Domenech, M., Escribano, R., Fernández-Parra, E., Gallardo, E., García-Carbonero, I., García, R., Garde, J., González del Alba, A., González, B., Hernández, A., Hernando, S., Jiménez, P., Laínez, N., Lorente, D., Luque, R., Martínez, E., Medina, A., Méndez-Vidal, M.J., Montesa, A., Morales, R., Olmos David, Pérez-Gracia, J.L., Pérez-Valderrama, B., Pinto, Á., Piulats, J., Puente, J., Querol, R., Rodríguez-Vida, A., Romero-Laorden, N., Sáez, M.I., Vázquez, S., Vélez, E., Villa-Guzmán, J.C., Villatoro, R., Zambrana, C., Gleave, M.E., Wyatt, A.W., Olmos, D., Chi, K.N., Castro, E.

“…A common polymorphism (1245A>C) in the HSD3B1 gene is associated with increased de novo synthesis of androgens and worse outcomes in men treated with…”
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Fragmentomic analysis of circulating tumor DNA-targeted cancer panels by Helzer, K.T., Sharifi, M.N., Sperger, J.M., Shi, Y., Annala, M., Bootsma, M.L., Reese, S.R., Taylor, A., Kaufmann, K.R., Krause, H.K., Schehr, J.L., Sethakorn, N., Kosoff, D., Kyriakopoulos, C., Burkard, M.E., Rydzewski, N.R., Yu, M., Harari, P.M., Bassetti, M., Blitzer, G., Floberg, J., Sjöström, M., Quigley, D.A., Dehm, S.M., Armstrong, A.J., Beltran, H., McKay, R.R., Feng, F.Y., O’Regan, R., Wisinski, K.B., Emamekhoo, H., Wyatt, A.W., Lang, J.M., Zhao, S.G.

“…The isolation of cell-free DNA (cfDNA) from the bloodstream can be used to detect and analyze somatic alterations in circulating tumor DNA (ctDNA), and…”
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Are biological communities in naturally unproductive streams resistant to additional anthropogenic stressors? by Annala, M., Mykrä, H., Tolkkinen, M., Kauppila, T., Muotka, T.

“…Studies on the interactive responses to multiple simultaneously acting stressors have focused on individual or population-level responses in laboratory…”
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Detection of circulating tumor DNA in de novo metastatic castrate sensitive prostate cancer by Struss, W.J., Vandekerkhove, G., Annala, M., Chi, K.N., Gleave, M.E., Wyatt, A.

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Predicting the constraint effect of environmental characteristics on macroinvertebrate density and diversity using quantile regression mixed model by Fornaroli, Riccardo, Cabrini, R., Sartori, L., Marazzi, F., Vracevic, D., Mezzanotte, V., Annala, M., Canobbio, S.

“…Various factors, such as habitat availability, competition for space, predation, temperature, nutrient supplies, presence of waterfalls, flow variability and…”
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A randomized phase II study of cabazitaxel (CAB) vs (ABI) abiraterone or (ENZ) enzalutamide in poor prognosis metastatic castration-resistant prostate cancer (mCRPC) by Chi, K.N., Taavitsainen, S., Iqbal, N., Ferrario, C., Ong, M., Wadhwa, D., Hotte, S.J., Lo, G., Tran, B., Azad, A., Wood, L., Gingerich, J.R., North, S., Pezaro, C.V., Ruether, D., Sridhar, S.S., Annala, M., Bacon, J., Wyatt, A.W.

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Utilization of poly(methyl methacrylate) – carbon nanotube and polystyrene – carbon nanotube in situ polymerized composites as masterbatches for melt mixing by Annala, M., Lahelin, M., Seppala, J.

“…Carbon nanotubes (CNTs) were melt mixed directly or by using an in situ polymerized masterbatch into a matrix polymer, polystyrene (PS) or poly(methyl…”
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Overexpression of SNORD114-3 marks acute promyelocytic leukemia by Liuksiala, T, Teittinen, K J, Granberg, K, Heinäniemi, M, Annala, M, Mäki, M, Nykter, M, Lohi, O

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P10.15.A THE ROLE OF NONCODING RNAS IN THE PROGRESSION OF IDH-MUTANT ASTROCYTOMAS TO GRADE 4 by Hartewig, A, Jaatinen, S, Annala, M, Helén, P, Haapasalo, J, Zhang, W, Haapasalo, H, Nykter, M, Rautajoki, K J

“…Abstract BACKGROUND Low grade IDHmutant astrocytomas are heterogeneous brain tumors that have a prognosis of 7-10 years. However, this prognosis is…”
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Effect of riparian soil moisture on bacterial, fungal and plant communities and microbial decomposition rates in boreal stream-side forests by Annala, M.J., Lehosmaa, K., Ahonen, S.H.K., Karttunen, K., Markkola, A.M., Puumala, I., Mykrä, H.

“…•Soil moisture influences plant and bacterial diversity, but not fungal.•Microbial driven decomposition is faster in moist riparian areas than on dry…”
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796PDDetection of circulating tumor DNA in de novo metastatic castrate sensitive prostate cancer by Struss, W J, Vandekerkhove, G, Annala, M, Chi, K N, Gleave, M E, Wyatt, A

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Somatic features of response and relapse in non-muscle invasive bladder cancer treated with intravesical Bacillus Calmette–Guérin by Müller, D.C., Bacon, J.V.W., Ritch, E., Dugas, S.G., Vandekerkhove, G., Annala, M., Black, P.C., Seifert, H., Bubendorf, L., Wyatt, A.W., Rentsch, C.A.

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Using liquid biopsy to assess the genomic landscape of metastatic urothelial carcinoma by Todenhöfer, T, Vandekerkhove, G, Struss, W, Annala, M, Beja, K, Eigl, B, Mischinger, J, Stenzl, A, Black, P, Wyatt, A

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Neoadjuvant hormonal therapies induce the expression of AR transcript variants by Tammela, T, Kallio, H, Annala, M, Brofeldt, A, Hieta, R, Kivinummi, K, Nykter, M, Lilja, H, Bova, G, Visakorpi, T

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