Search Results - "Anna Penalba"
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Evaluation and Characterization of Post-Stroke Lung Damage in a Murine Model of Cerebral Ischemia
Published in International journal of molecular sciences (22-07-2022)“…After stroke and other brain injuries, there is a high incidence of respiratory complications such as pneumonia or acute lung injury. The molecular mechanisms…”
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2
Factors secreted by endothelial progenitor cells enhance neurorepair responses after cerebral ischemia in mice
Published in PloS one (04-09-2013)“…Cell therapy with endothelial progenitor cells (EPCs) has emerged as a promising strategy to regenerate the brain after stroke. Here, we aimed to investigate…”
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3
Plasmatic retinol‐binding protein 4 and glial fibrillary acidic protein as biomarkers to differentiate ischemic stroke and intracerebral hemorrhage
Published in Journal of neurochemistry (01-01-2016)“…A rapid differentiation of acute ischemic stroke and intracerebral hemorrhage (ICH) is essential for an adequate treatment and to promote a better outcome. Our…”
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Blood-biomarkers and devices for atrial fibrillation screening: Lessons learned from the AFRICAT (Atrial Fibrillation Research In CATalonia) study
Published in PloS one (23-08-2022)“…Background and objective AFRICAT is a prospective cohort study intending to develop an atrial fibrillation (AF) screening program through the combination of…”
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5
New candidate blood biomarkers potentially associated with white matter hyperintensities progression
Published in Scientific reports (12-07-2021)“…We aimed to discover blood biomarkers associated with longitudinal changes in white matter hyperintensities (WMH). This study was divided into a discovery…”
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Single Cell Immuno-Laser Microdissection Coupled to Label-Free Proteomics to Reveal the Proteotypes of Human Brain Cells After Ischemia
Published in Molecular & cellular proteomics (01-01-2018)“…Cerebral ischemia entails rapid tissue damage in the affected brain area causing devastating neurological dysfunction. How each component of the neurovascular…”
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7
Vascular MMP-9/TIMP-2 and Neuronal MMP-10 Up-Regulation in Human Brain after Stroke: A Combined Laser Microdissection and Protein Array Study
Published in Journal of proteome research (05-06-2009)“…Matrix Metalloproteinases (MMPs) play an important role in brain injury after ischemic stroke. In the present study, we aimed to assess the global expression…”
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8
Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release
Published in Journal of leukocyte biology (01-07-2008)“…Recombinant tissue plasminogen activator (t‐PA), the only approved stroke treatment, is used for clot lysis within the occluded brain artery. Unfortunately,…”
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Mobilization, endothelial differentiation and functional capacity of endothelial progenitor cells after ischemic stroke
Published in Microvascular research (01-12-2010)“…Endothelial progenitor cells (EPCs) have introduced new possibilities for cell-based vasculogenesis treatment after stroke. In this study we quantified…”
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10
MMP-2/MMP-9 Plasma Level and Brain Expression in Cerebral Amyloid Angiopathy-Associated Hemorrhagic Stroke
Published in Brain pathology (Zurich, Switzerland) (01-03-2012)“…Cerebral amyloid angiopathy (CAA) is one of the main causes of intracerebral hemorrhage (ICH) in the elderly. Matrix metalloproteinases (MMPs) have been…”
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11
Blood biomarker changes following therapeutic hypothermia in ischemic stroke
Published in Brain and behavior (01-11-2023)“…Abstract Introduction Therapeutic hypothermia is a promising candidate for stroke treatment although its efficacy has not yet been demonstrated in patients…”
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12
Functional Recovery and Serum Angiogenin Changes According to Intensity of Rehabilitation Therapy After Stroke
Published in Frontiers in neurology (25-11-2021)“…Rehabilitation is still the only treatment available to improve functional status after the acute phase of stroke. Most clinical guidelines highlight the need…”
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13
Blood-Based Biomarkers to Search for Atrial Fibrillation in High-Risk Asymptomatic Individuals and Cryptogenic Stroke Patients
Published in Frontiers in cardiovascular medicine (04-07-2022)“…Background Atrial fibrillation (AF) increases the risk of ischemic stroke in asymptomatic individuals and may be the underlying cause of many cryptogenic…”
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14
Exome Sequencing and Clot Lysis Experiments Demonstrate the R458C Mutation of the Alpha Chain of Fibrinogen to be Associated with Impaired Fibrinolysis in a Family with Thrombophilia
Published in Journal of Atherosclerosis and Thrombosis (01-01-2016)“…Aim: We report the study of a familial rare disease with recurrent venous thromboembolic events that remained undiagnosed for many years using standard…”
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15
Proteins and pathways in atrial fibrillation and atrial cardiomyopathy underlying cryptogenic stroke
Published in International journal of cardiology. Heart & vasculature (01-04-2022)“…Atrial fibrillation (AF) is one of the most prevalent causes of cryptogenic stroke. Also, apart from AF itself, structural and remodelling changes in the atria…”
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16
VAP-1/SSAO plasma activity and brain expression in human hemorrhagic stroke
Published in Cerebrovascular diseases (Basel, Switzerland) (01-01-2012)“…Vascular adhesion protein-1 (VAP-1) is a cell surface and circulating enzyme that belongs to the semicarbazide-sensitive amine oxidase (SSAO) family, which…”
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17
Biomarkers predictive value for early diagnosis of Stroke‐Associated Pneumonia
Published in Annals of clinical and translational neurology (01-09-2019)“…To confirm the diagnostic accuracy of candidate biomarkers in stroke‐associated pneumonia (SAP), we prospectively enrolled ischemic stroke patients with…”
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Poststroke c-reactive protein is a powerful prognostic tool among candidates for thrombolysis
Published in Stroke (1970) (01-05-2006)“…After acute stroke, an increased level of C-reactive protein (CRP) measured at discharge predicts unfavorable outcome. We sought to investigate whether CRP…”
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19
Role of endogenous granulocyte-macrophage colony stimulating factor following stroke and relationship to neurological outcome
Published in Current neurovascular research (01-11-2009)“…Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is a proinflammatory cytokine with neuroprotective and angiogenic properties demonstrated in animal…”
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20
Exome Sequencing and Clot Lysis Experiments Demonstrate the R458C Mutation of the Alpha Chain of Fibrinogen to be Associated with Impaired Fibrinolysis in a Family with Thrombophilia
Published in Journal of Atherosclerosis and Thrombosis (2016)“…[Aim]: We report the study of a familial rare disease with recurrent venous thromboembolic events that remained undiagnosed for many years using standard…”
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