Search Results - "Ann M. Donnelly"

Aminopyridinecarboxamide-based inhibitors: Structure–activity relationship by Bonafoux, Dominique F., Bonar, Sheri L., Clare, Michael, Donnelly, Ann M., Glaenzer, Jeanette L., Guzova, Julia A., Huang, He, Kishore, Nandidni N., Koszyk, Francis J., Lennon, Patrick J., Libby, Adam, Mathialagan, Sumathy, Oburn, David S., Rouw, Sharon A, Sommers, Cynthia D., Tripp, Catherine S., Vanella, Lori J., Weier, Richard, Wolfson, Serge G., Huang, Horng-Chih

“…Aminopyridinecarboxamide-based iKK-2 inhibitors were synthesized and tested leading to the 2-amino-5-chloropyridine-4-carboxamides as potent inhibitors with…”
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Circular Permutation of the Granulocyte Colony-Stimulating Factor Receptor Agonist Domain of Myelopoietin by McWherter, Charles A, Feng, Yiqing, Zurfluh, Linda L, Klein, Barbara K, Baganoff, Mark P, Polazzi, Joseph O, Hood, William F, Paik, Kumnan, Abegg, Ann L, Grabbe, Edith S, Shieh, Jeng-Jong, Donnelly, Ann M, McKearn, John P

“…Myelopoietins (MPOs) are a family of engineered dual interleukin-3 (IL-3) and granulocyte colony-stimulating factor (G-CSF) receptor agonists that are superior…”
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Kinetic Mechanisms of IκB-related Kinases (IKK) Inducible IKK and TBK-1 Differ from IKK-1/IKK-2 Heterodimer by Huynh, Q. Khai, Kishore, Nandini, Mathialagan, Sumathy, Donnelly, Ann M., Tripp, Catherine S.

“…Nuclear factor-κB activation depends on phosphorylation and degradation of its inhibitor protein, IκB. The phosphorylation of IκBα on Ser32 and Ser36 is…”
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Kinetic mechanisms of IkappaB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer by Huynh, Q Khai, Kishore, Nandini, Mathialagan, Sumathy, Donnelly, Ann M, Tripp, Catherine S

“…Nuclear factor-kappaB activation depends on phosphorylation and degradation of its inhibitor protein, IkappaB. The phosphorylation of IkappaBalpha on Ser(32)…”
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Kinetic Mechanisms of IκB-related Kinases (IKK) Inducible IKK and TBK-1 Differ from IKK-1/IKK-2 Heterodimer by Q. Khai Huynh, Nandini Kishore, Sumathy Mathialagan, Ann M. Donnelly, Catherine S. Tripp

“…Nuclear factor-κB activation depends on phosphorylation and degradation of its inhibitor protein, IκB. The phosphorylation of IκBα on Ser 32 and Ser 36 is…”
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Use of combinatorial mutagenesis to select for multiply substituted human interleukin-3 variants with improved pharmacologic properties by Klein, Barbara K., Olins, Peter O., Bauer, S.Christopher, Caparon, Maire H., Easton, Alan M., Braford, Sarah R., Abrams, Mark A., Klover, Jon A., Paik, Kumnan, Thomas, John W., Hood, William F., Shieh, Jeng-Jong, Polazzi, Joseph O., Donnelly, Ann M., Zeng, David L., Welply, Joseph K., McKearn, John P.

“…A combinatorial mutagenesis strategy was used to create a collection of nearly 500 variants of human interleukin 3 (IL-3), each with four to nine amino acid…”
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Committee and Discussion Group News by Reinert, M. Ann, Mulac, Carolyn M., DeDonato, Ree, Wall, Thomas B., Donnelly, Ann M., Angell, Lucinda

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