Search Results - "Ankur Rakesh"

Autophagy based cellular physiological strategies target oncogenic progression by Kumar, Prashant, Jagtap, Yuvraj Anandrao, Patwa, Som Mohanlal, Kinger, Sumit, Dubey, Ankur Rakesh, Prajapati, Vijay Kumar, Dhiman, Rohan, Poluri, Krishna Mohan, Mishra, Amit

“…Evidence accumulated from past findings indicates that defective proteostasis may contribute to risk factors for cancer generation. Irregular assembly of…”
Get full text

Cholera epidemic in Yemen, 2016–18: an analysis of surveillance data by Camacho, Anton, Bouhenia, Malika, Alyusfi, Reema, Alkohlani, Abdulhakeem, Naji, Munna Abdulla Mohammed, de Radiguès, Xavier, Abubakar, Abdinasir M, Almoalmi, Abdulkareem, Seguin, Caroline, Sagrado, Maria Jose, Poncin, Marc, McRae, Melissa, Musoke, Mohammed, Rakesh, Ankur, Porten, Klaudia, Haskew, Christopher, Atkins, Katherine E, Eggo, Rosalind M, Azman, Andrew S, Broekhuijsen, Marije, Saatcioglu, Mehmet Akif, Pezzoli, Lorenzo, Quilici, Marie-Laure, Al-Mesbahy, Abdul Rahman, Zagaria, Nevio, Luquero, Francisco J

“…In war-torn Yemen, reports of confirmed cholera started in late September, 2016. The disease continues to plague Yemen today in what has become the largest…”
Get full text

Proteome Linked Biochemical Targets: Can Repair Defective Cellular Physiological Mechanisms? by Dubey, Ankur Rakesh, Prasad, Amit, Poluri, Krishna Mohan, Kumar, Amit, Kumar, Awanish, Mishra, Amit

“…Major cause of proteopathies is the accumulation of unwanted mutant and aberrant proteins. We know that imperfect ageing is one of chief risk factor for most…”
Get full text

Single-Dose Cholera Vaccine in Response to an Outbreak in Zambia by Ferreras, Eva, Chizema-Kawesha, Elizabeth, Blake, Alexandre, Chewe, Orbrie, Mwaba, John, Zulu, Gideon, Poncin, Marc, Rakesh, Ankur, Page, Anne-Laure, Stoitsova, Savina, Voute, Caroline, Uzzeni, Florent, Robert, Hugues, Serafini, Micaela, Matapo, Belem, Eiros, Jose-María, Quilici, Marie-Laure, Pezzoli, Lorenzo, Azman, Andrew S, Cohuet, Sandra, Ciglenecki, Iza, Malama, Kennedy, Luquero, Francisco J

“…The effectiveness of a single dose of an oral cholera vaccine was assessed during a cholera outbreak in Zambia…”
Get full text

Resveratrol Promotes LRSAM1 E3 Ubiquitin Ligase-Dependent Degradation of Misfolded Proteins Linked with Neurodegeneration by Dubey, Ankur Rakesh, Mishra, Ribhav, Sundaria, Naveen, Jagtap, Yuvraj Anandrao, Kumar, Prashant, Kinger, Sumit, Choudhary, Akash, Jha, Hem Chandra, Prasad, Amit, Gutti, Ravi Kumar, Mishra, Amit

“…BACKGROUND/AIMS: Cells require regular maintenance of proteostasis. Synthesis of new polypeptides and elimination of damaged or old proteins is an…”
Get full text

Proteasome Based Molecular Strategies Against Improper Cellular Proliferation by Dubey, Ankur Rakesh, Kinger, Sumit, Jagtap, Yuvraj Anandrao, Patwa, Som Mohanlal, Kumar, Prashant, Singh, Sarika, Kumar, Amit, Kumar, Awanish, Mishra, Amit

“…Cells contain several proteins that routinely fulfill multiple requirements for normal physiological survival. Proteostasis dysfunction is linked with…”
Get full text

Disturb mitochondrial associated proteostasis: Neurodegeneration and imperfect ageing by Jagtap, Yuvraj Anandrao, Kumar, Prashant, Kinger, Sumit, Dubey, Ankur Rakesh, Choudhary, Akash, Gutti, Ravi Kumar, Singh, Sarika, Jha, Hem Chandra, Poluri, Krishna Mohan, Mishra, Amit

“…The disturbance in mitochondrial functions and homeostasis are the major features of neuron degenerative conditions, like Parkinson's disease, Amyotrophic…”
Get full text

Molecular Chaperones' Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis by Kinger, Sumit, Dubey, Ankur Rakesh, Kumar, Prashant, Jagtap, Yuvraj Anandrao, Choudhary, Akash, Kumar, Amit, Prajapati, Vijay Kumar, Dhiman, Rohan, Mishra, Amit

“…Amyotrophic lateral sclerosis (ALS) is a neuronal degenerative condition identified via a build-up of mutant aberrantly folded proteins. The native folding of…”
Get full text

Improved vaccination coverage after two rounds of multi-antigenic catch-up vaccination in Mauritania by Pagola-Ugarte, Maider, Rakesh, Ankur, Gil-Cuesta, Julita, Kidinda, David, Kelly, Thierno Moctar, Zahaf, Sidi, Mahmoud, Mohamed Mahmoud O Ely, Salem, Mohamedou O Mohamed, Houmeid, Mbareck, Cheikh, Dah, Ouldzeidoune, Naceredine, Bachy, Catherine

“…Although Mauritania carried out its Expanded Programme on Immunization (EPI), in 2015 the goal of vaccination coverage (VC) remained unmet in Bassikounou…”
Get full text

Proteostasis defects: Medicinal challenges of imperfect aging & neurodegeneration by Kumar, Prashant, Choudhary, Akash, Kinger, Sumit, Jagtap, Yuvraj Anandrao, Dubey, Ankur Rakesh, Gutti, Ravi Kumar, Chitkara, Deepak, Suresh, Anil K., Mishra, Amit

“…A prolonged healthy life is based on the optimal activity of an organism’s organ systems, and healthy cells are at the core of this proper functioning…”
Get full text

Acetaminophen induces mitochondrial apoptosis through proteasome dysfunctions by Jagtap, Yuvraj Anandrao, Kumar, Prashant, Dubey, Ankur Rakesh, Kinger, Sumit, Choudhary, Akash, Karmakar, Surojit, Lal, Girdhari, Kumar, Awanish, Kumar, Amit, Prasad, Amit, Mishra, Amit

“…Acetaminophen is a known antipyretic and non-opioid analgesic for mild pain and fever. Numerous studies uncover their hidden chemotherapeutics applications,…”
Get full text

Lanosterol elevates cytoprotective response through induced-proteasomal degradation of aberrant proteins by Kinger, Sumit, Jagtap, Yuvraj Anandrao, Dubey, Ankur Rakesh, Kumar, Prashant, Choudhary, Akash, Dhiman, Rohan, Prajapati, Vijay Kumar, Chitkara, Deepak, Poluri, Krishna Mohan, Mishra, Amit

“…Efficient protein synthesis is a basic requirement of our cells to replace the old or defective proteins from the intrinsic crowded biomolecular environment…”
Get full text

Trehalose Promotes Clearance of Proteotoxic Aggregation of Neurodegenerative Disease-Associated Aberrant Proteins by Kumar, Prashant, Kinger, Sumit, Dubey, Ankur Rakesh, Jagtap, Yuvraj Anandrao, Choudhary, Akash, Prasad, Amit, Jha, Hem Chandra, Dhiman, Rohan, Gutti, Ravi Kumar, Mishra, Amit

“…Accumulation of misfolded proteins compromises overall cellular health and fitness. The failure to remove misfolded proteins is a critical reason for their…”
Get full text

Genomic insights into the 2016–2017 cholera epidemic in Yemen by Weill, François-Xavier, Domman, Daryl, Njamkepo, Elisabeth, Almesbahi, Abdullrahman A., Naji, Mona, Nasher, Samar Saeed, Rakesh, Ankur, Assiri, Abdullah M., Sharma, Naresh Chand, Kariuki, Samuel, Pourshafie, Mohammad Reza, Rauzier, Jean, Abubakar, Abdinasir, Carter, Jane Y., Wamala, Joseph F., Seguin, Caroline, Bouchier, Christiane, Malliavin, Thérèse, Bakhshi, Bita, Abulmaali, Hayder H. N., Kumar, Dhirendra, Njoroge, Samuel M., Malik, Mamunur Rahman, Kiiru, John, Luquero, Francisco J., Azman, Andrew S., Ramamurthy, Thandavarayan, Thomson, Nicholas R., Quilici, Marie-Laure

“…Yemen is currently experiencing, to our knowledge, the largest cholera epidemic in recent history. The first cases were declared in September 2016, and over…”
Get full text

Point‐of‐care viral load monitoring: outcomes from a decentralized HIV programme in Malawi by Nicholas, Sarala, Poulet, Elisabeth, Wolters, Liselotte, Wapling, Johanna, Rakesh, Ankur, Amoros, Isabel, Szumilin, Elisabeth, Gueguen, Monique, Schramm, Birgit

“…Introduction Routinely monitoring the HIV viral load (VL) of people living with HIV (PLHIV) on anti‐retroviral therapy (ART) facilitates intensive adherence…”
Get full text

Ubiquitin ligase LRSAM1 suppresses neurodegenerative diseases linked aberrant proteins induced cell death by Mishra, Ribhav, Amanullah, Ayeman, Upadhyay, Arun, Dhiman, Rohan, Dubey, Ankur Rakesh, Singh, Sarika, Prasad, Amit, Mishra, Amit

“…[Display omitted] •LRSAM1 can function as a quality control E3 Ubiquitin Ligase.•Recruitment of LRSAM1 towards misfolded proteins.•LRSAM1 levels induced under…”
Get full text

Itraconazole Confers Cytoprotection Against Neurodegenerative Disease-Associated Abnormal Protein Aggregation by Dubey, Ankur Rakesh, Mishra, Ribhav, Jagtap, Yuvraj Anandrao, Kinger, Sumit, Kumar, Prashant, Dhiman, Rohan, Ghosh, Somnath, Singh, Sarika, Prasad, Amit, Jana, Nihar Ranjan, Mishra, Amit

“…Cells perform regular maintenance to avoid the accumulation of misfolded proteins. Prolonged accumulation of these proteotoxic inclusions generates potential…”
Get full text

Improper Proteostasis: Can It Serve as Biomarkers for Neurodegenerative Diseases? by Dubey, Ankur Rakesh, Patwa, Som Mohanlal, Kinger, Sumit, Jagtap, Yuvraj Anandrao, Kumar, Prashant, Singh, Sarika, Dhiman, Rohan, Jha, Hem Chandra, Mishra, Amit

“…Cells synthesize new proteins after multiple molecular decisions. Damage of existing proteins, accumulation of abnormal proteins, and basic requirement of new…”
Get full text

Implementation and operational feasibility of SAMBA I HIV‐1 semi‐quantitative viral load testing at the point‐of‐care in rural settings in Malawi and Uganda by Gueguen, Monique, Nicholas, Sarala, Poulet, Elisabeth, Schramm, Birgit, Szumilin, Elisabeth, Wolters, Liselotte, Wapling, Johanna, Ajule, Ephrahim, Rakesh, Ankur, Mwenda, Reuben, Kiyaga, Charles, Balkan, Suna

“…Objective We monitored a large‐scale implementation of the Simple Amplification‐Based Assay semi‐quantitative viral load test for HIV‐1 version I (SAMBA I…”
Get full text

LRSAM1 E3 ubiquitin ligase promotes proteasomal clearance of E6-AP protein by Mishra, Ribhav, Joshi, Vibhuti, Upadhyay, Arun, Amanullah, Ayeman, Dubey, Ankur Rakesh, Singh, Sarika, Dubey, Vikash Kumar, Poluri, Krishna Mohan, Jana, Nihar Ranjan, Mishra, Amit

“…Numerous proteins participate and actively contribute to the various cellular mechanisms, where several of them are crucial for regular metabolism, including…”
Get full text