Search Results - "Anke Osterloh"

The neglected challenge: Vaccination against rickettsiae by Osterloh, Anke

“…Over the last decades, rickettsioses are emerging worldwide. These diseases are caused by intracellular bacteria. Although rickettsioses can be treated with…”
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Vaccination against Bacterial Infections: Challenges, Progress, and New Approaches with a Focus on Intracellular Bacteria by Osterloh, Anke

“…Many bacterial infections are major health problems worldwide, and treatment of many of these infectious diseases is becoming increasingly difficult due to the…”
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Vaccine Design and Vaccination Strategies against Rickettsiae by Osterloh, Anke

“…Rickettsioses are febrile, potentially lethal infectious diseases that are a serious health threat, especially in poor income countries. The causative agents…”
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GroEL is an immunodominant surface-exposed antigen of Rickettsia typhi by Rauch, Jessica, Barton, Jessica, Kwiatkowski, Marcel, Wunderlich, Malte, Steffen, Pascal, Moderzynski, Kristin, Papp, Stefanie, Höhn, Katharina, Schwanke, Hella, Witt, Susanne, Richardt, Ulricke, Mehlhoop, Ute, Schlüter, Hartmut, Pianka, Verena, Fleischer, Bernhard, Tappe, Dennis, Osterloh, Anke

“…Rickettsioses are neglected and emerging potentially fatal febrile diseases that are caused by obligate intracellular bacteria, rickettsiae. Rickettsia (R.)…”
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Author Correction: Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease by Noelker, Carmen, Morel, Lydie, Lescot, Thomas, Osterloh, Anke, Alvarez-Fischer, Daniel, Breloer, Minka, Henze, Carmen, Depboylu, Candan, Skrzydelski, Delphine, Michel, Patrick P., Dodel, Richard C., Lu, Lixia, Hirsch, Etienne C., Hunot, Stéphane, Hartmann, Andreas

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Synergistic and Differential Modulation of Immune Responses by Hsp60 and Lipopolysaccharide by Osterloh, Anke, Kalinke, Ulrich, Weiss, Siegfried, Fleischer, Bernhard, Breloer, Minka

“…Activation of professional antigen-presenting cells (APC) is a crucial step in the initiation of an efficient immune response. In this study we show that Hsp60…”
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Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells by Papp, Stefanie, Moderzynski, Kristin, Rauch, Jessica, Heine, Liza, Kuehl, Svenja, Richardt, Ulricke, Mueller, Heidelinde, Fleischer, Bernhard, Osterloh, Anke

“…Rickettsia (R.) typhi is the causative agent of endemic typhus, an emerging febrile disease that is associated with complications such as pneumonia,…”
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CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity by Moderzynski, Kristin, Papp, Stefanie, Rauch, Jessica, Heine, Liza, Kuehl, Svenja, Richardt, Ulricke, Fleischer, Bernhard, Osterloh, Anke

“…Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia,…”
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Cytotoxic effector functions of T cells are not required for protective immunity against fatal Rickettsia typhi infection in a murine model of infection: Role of TH1 and TH17 cytokines in protection and pathology by Moderzynski, Kristin, Heine, Liza, Rauch, Jessica, Papp, Stefanie, Kuehl, Svenja, Richardt, Ulricke, Fleischer, Bernhard, Osterloh, Anke

“…Endemic typhus caused by Rickettsia (R.) typhi is an emerging febrile disease that can be fatal due to multiple organ pathology. Here we analyzed the…”
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Differential regulation of marginal zone and follicular B cell responses by CD83 by Uhde, Melanie, Kuehl, Svenja, Richardt, Ulricke, Fleischer, Bernhard, Osterloh, Anke

“…Transgenic over-expression of CD83 on B cells leads to a reduced response to BCR engagement but to an enhanced secretion of IL-10 upon LPS stimulation. In this…”
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Heat shock protein 60 (HSP60) stimulates neutrophil effector functions by Osterloh, Anke, Geisinger, Frank, Piédavent, Melanie, Fleischer, Bernhard, Brattig, Norbert, Breloer, Minka

“…HSP60 functions as a chemoattractant and activator of neutrophil granulocytes. Neutrophil granulocytes belong to the first cells that enter sites of infection,…”
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Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12 by Osterloh, Anke, Veit, Alexandra, Gessner, André, Fleischer, Bernhard, Breloer, Minka

“…Heat shock protein (Hsp) 60 is thought to function as endogenous danger signal by activating professional antigen-presenting cells (APC) through toll-like…”
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Immune response against rickettsiae: lessons from murine infection models by Osterloh, Anke

“…Rickettsiae are small intracellular bacteria that can cause life-threatening febrile diseases. Rickettsioses occur worldwide with increasing incidence…”
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Lipopolysaccharide-free Heat Shock Protein 60 Activates T Cells by Osterloh, Anke, Meier-Stiegen, Franziska, Veit, Alexandra, Fleischer, Bernhard, von Bonin, Arne, Breloer, Minka

“…A possible function of eukaryotic heat shock protein 60 (Hsp60) as endogenous danger signal has been controversially discussed in the past. Hsp60 was shown to…”
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A new view on cutaneous dendritic cell subsets in experimental leishmaniasis by RITTER, Uwe, OSTERLOH, Anke

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Heat shock proteins: linking danger and pathogen recognition by Osterloh, Anke, Breloer, Minka

“…Besides their central function in protein folding and transport within the cell, heat shock proteins (HSP) have been shown to modulate innate and adaptive…”
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Persisting Rickettsia typhi Causes Fatal Central Nervous System Inflammation by Osterloh, Anke, Papp, Stefanie, Moderzynski, Kristin, Kuehl, Svenja, Richardt, Ulricke, Fleischer, Bernhard

“…Rickettsioses are emerging febrile diseases caused by obligate intracellular bacteria belonging to the family Rickettsiaceae. Rickettsia typhi belongs to the…”
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Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease by Noelker, Carmen, Morel, Lydie, Lescot, Thomas, Osterloh, Anke, Alvarez-Fischer, Daniel, Breloer, Minka, Henze, Carmen, Depboylu, Candan, Skrzydelski, Delphine, Michel, Patrick P., Dodel, Richard C., Lu, Lixia, Hirsch, Etienne C., Hunot, Stéphane, Hartmann, Andreas

“…In mammalians, toll-like receptors (TLR) signal-transduction pathways induce the expression of a variety of immune-response genes, including inflammatory…”
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GFPuv-Expressing Recombinant Rickettsia typhi: a Useful Tool for the Study of Pathogenesis and CD8 + T Cell Immunology in R. typhi Infection by Hauptmann, Matthias, Burkhardt, Nicole, Munderloh, Ulrike, Kuehl, Svenja, Richardt, Ulricke, Krasemann, Susanne, Hartmann, Kristin, Krech, Till, Fleischer, Bernhard, Keller, Christian, Osterloh, Anke

“…is the causative agent of endemic typhus, a disease with increasing incidence worldwide that can be fatal. Because of its obligate intracellular life style,…”
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Orientia tsutsugamushi Is Highly Susceptible to the RNA Polymerase Switch Region Inhibitor Corallopyronin A In Vitro and In Vivo by Kock, Fredericke, Hauptmann, Matthias, Osterloh, Anke, Schäberle, Till F, Poppert, Sven, Frickmann, Hagen, Menzel, Klaus-Dieter, Peschel, Gundela, Pfarr, Kenneth, Schiefer, Andrea, König, Gabriele M, Hoerauf, Achim, Fleischer, Bernhard, Keller, Christian

“…Scrub typhus is a potentially lethal infection caused by the obligate intracellular bacterium Reports on the emergence of doxycycline-resistant strains…”
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