Search Results - "Ankala, Ramya"

Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice by Hu, Xiaomeng, Gattis, Corie, Olroyd, Ari G, Friera, Annabelle M, White, Kathy, Young, Chi, Basco, Ron, Lamba, Meghan, Wells, Frank, Ankala, Ramya, Dowdle, William E, Lin, August, Egenberger, Kyla, Rukstalis, J Michael, Millman, Jeffrey R, Connolly, Andrew J, Deuse, Tobias, Schrepfer, Sonja

“…Transplantation of allogeneic pancreatic donor islets has successfully been performed in selected patients with difficult-to-control insulin-dependent diabetes…”
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Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques by Hu, Xiaomeng, White, Kathy, Olroyd, Ari G., DeJesus, Rowena, Dominguez, Antonia A., Dowdle, William E., Friera, Annabelle M., Young, Chi, Wells, Frank, Chu, Elaine Y., Ito, Cade Ellis, Krishnapura, Harini, Jain, Surbhi, Ankala, Ramya, McGill, Trevor J., Lin, August, Egenberger, Kyla, Gagnon, Allison, Michael Rukstalis, J., Hogrebe, Nathaniel J., Gattis, Corie, Basco, Ron, Millman, Jeffrey R., Kievit, Paul, Davis, Mark M., Lanier, Lewis L., Connolly, Andrew J., Deuse, Tobias, Schrepfer, Sonja

“…Genetic engineering of allogeneic cell therapeutics that fully prevents rejection by a recipient’s immune system would abolish the requirement for…”
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Efficient and Specific In Vivo Genetic Engineering of Human Hematopoietic Stem Progenitor Cells without Selective Conditioning by Botchkarev, Vladimir V, Harrington, Sean, Justen, Alexander, Kimber, Casey, Kapuria, Anjali, Xu, Yuanxin, Haugh, Kelsey, Ankala, Ramya, Kipniss, Nathan, de Jesus, Rowena, Adewale, Funmi, Daniels, Kathy, Crocker, Samantha, Liang, Anna, Joyce, Shannon, Smith, Derek, Wong, Athena, Berlfein, Valeria, Amatya, Shirisha, Cruite, Patricia, Usmani, Shariq, Ruzo, Albert, Ferland, Benjamin, Chandra, Sundeep, Stoppato, Matteo, Trudeau, Kyle, Rebar, Edward, Shah, Jagesh, Biasco, Luca

“…Achieving in vivo genetic engineering of hematopoietic stem progenitor cells (HSPC) has the potential to transform treatment for hematological disorders. An…”
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Efficient and Specific Multi-Locus Editing of Allogeneic CAR T Cells for Hypoimmunity during Large Scale Manufacture Using Cas12b by Chaivorapol, Christina, Beauchesne, Pascal, De Jesus, Rowena, Dowdle, William E, Chen, Xiaoyu, Bayley, Alison, Qiu, Yunjiang, Birnberg, Andrew, Zheng, Yu, Montalbano, Antonino, Liu, Angela, Zafar, Misbah, Manner, Karl, Ankala, Ramya, Tham, Eleonore, Shah, Heer, Lam, Ben, Lock, Jaclyn, Weng, Lindong, Watts, Kate, Valdiosera, Amanda, Davis, Kimberly, Wang, Lei, Kangeyan, PhD, Divy, Devos, Nicolas, Wong, Athena, Lih, Jason, Rebar, Edward J

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Abstract 4091: Engineered hypoimmune CAR T cells provide lasting tumor control in immunocompetent allogeneic humanized mice even with re-challenge by Hu, Xiaomeng, Beauchesne, Pascal, Manner, Karl, Gattis, Corie, Ngo, Priscilla, De Jesus, Rowena, Ankala, Ramya, Young, Chi, Wells, Frank, Weng, Lindong, White, Kathy, Dowdle, William E., Foster, Aaron, Fry, Terry J., Schrepfer, Sonja

“…Abstract Off-the-shelf CAR T cells potentially offer advantages over autologous strategies such as ease of manufacturing, quality control, off-the-shelf…”
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Investigating the Function and Epigenetic Regulation of ABCA3, a Novel LUAD Tumor Suppressor Gene by Ankala, Ramya S

“…Lung cancer accounts for the majority of cancer deaths in the US and worldwide. Lung adenocarcinoma (LUAD) is the most common histological subtype of non-small…”
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