Search Results - "Anisowicz, A"
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A novel protease homolog differentially expressed in breast and ovarian cancer
Published in Molecular medicine (Cambridge, Mass.) (01-09-1996)“…Using differential display (DD), we discovered a new member of the serine protease family of protein-cleaving enzymes, named protease M. The gene is most…”
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Constitutive Overexpression of a Growth-Regulated Gene in Transformed Chinese Hamster and Human Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1987)“…Comparison by subtractive hybridization of mRNAs revealed a moderately abundant message in highly tumorigenic CHEF/16 cells present at very low levels in…”
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An NF-kappa B-like transcription factor mediates IL-1/TNF-alpha induction of gro in human fibroblasts
Published in The Journal of immunology (1950) (15-07-1991)“…Normal human foreskin fibroblasts were used to examine transcriptional induction by IL-1 and TNF-alpha of the novel cytokine gro (melanoma growth-stimulating…”
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Functional Diversity of gro Gene Expression in Human Fibroblasts and Mammary Epithelial Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1988)“…Previous studies of gro and related genes that are overexpressed in transformed fibroblasts suggest that gro may encode a specific growth regulator. However,…”
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RNA genetics of breast cancer: maspin as paradigm
Published in Cold Spring Harbor Symposia on Quantitative Biology (1994)Get more information
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Re-expression of SPR1 in breast cancer cells by phorbol 12-myristate 13-acetate (PMA) or UV irradiation is mediated by the AP-1 binding site in the SPR1 promoter
Published in Molecular medicine (Cambridge, Mass.) (01-08-1999)“…Invasive tumor cells are characterized by multiple phenotypic changes as a result of the large number of cDNAs being differentially expressed in tumor cells…”
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Resistance of Human Cells to Tumorigenesis Induced by Cloned Transforming Genes
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1983)“…The transformation of human cells was examined by transfection of cloned oncogenic DNAs derived from the tumor virus simian virus 40 and from the human bladder…”
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A Mutation in the LDL Receptor–Related Protein 5 Gene Results in the Autosomal Dominant High–Bone-Mass Trait
Published in American journal of human genetics (01-01-2002)“…Osteoporosis is a complex disease that affects >10 million people in the United States and results in 1.5 million fractures annually. In addition, the high…”
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High Frequency of Large Spontaneous Deletions of DNA in Tumor-Derived CHEF Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1989)“…Spontaneous mutations arising at the HPRT locus were examined in 126 mutants recovered from a series of six CHEF-derived cell lines. Altered restriction…”
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Plasmid-Induced ``Hit-And-Run'' Tumorigenesis in Chinese Hamster Embryo Fibroblast (CHEF) Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1985)“…The Chinese hamster embryo fibroblast cell line CHEF/18 is readily transfected by plasmid DNA. In the present transfection studies with CHEF/18 cells, focus…”
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Azacytidine-Induced Tumorigenesis of CHEF/18 Cells: Correlated DNA Methylation and Chromosome Changes
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1983)“…5-Azacytidine (azaC), a drug that induces decreased methylation of DNA in mammalian cells, was shown previously to induce differentiation of mesenchymal cell…”
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Structural, regulatory, and functional studies of the GRO gene and protein
Published in Cytokines (1992)Get more information
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Identification, Cloning, and Characterization of Cystatin M, a Novel Cysteine Proteinase Inhibitor, Down-regulated in Breast Cancer
Published in The Journal of biological chemistry (10-01-1997)“…A novel human cystatin gene was identified in a differential display comparison aimed at the isolation of transcriptionally regulated genes involved in…”
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Maspin, a Serpin with Tumor-Suppressing Activity in Human Mammary Epithelial Cells
Published in Science (American Association for the Advancement of Science) (28-01-1994)“…A gene encoding a protein related to the serpin family of protease inhibitors was identified as a candidate tumor suppressor gene that may play a role in human…”
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Structure-based mutation analysis shows the importance of LRP5 β-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling
Published in Gene (15-04-2007)“…A single point mutation (G to T) in the low-density lipoprotein receptor related protein 5 (LRP5) gene results in a glycine to valine amino acid change (G171V)…”
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Identification of Three Related Human GRO Genes Encoding Cytokine Functions
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1990)“…The product of the human GRO gene is a cytokine with inflammatory and growth-regulatory properties; GRO is also called MGSA for melanoma growth-stimulatory…”
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Separation of Sarcoma Virus-Specific and Leukemia Virus-Specific Genetic Sequences of Moloney Sarcoma Virus
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1975)“…We have studied the nucleic acid sequences in nonproducer cells transformed by Moloney sarcoma virus or Abelson leukemia virus (two types of…”
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DNA Transfer of Focus- and Tumor-Forming Ability into Nontumorigenic CHEF Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1982)“…CHEF/18 fibroblastic cells derived from a Chinese hamster embryo are diploid and nontumorigenic and require multiple steps of chemical treatment and selection…”
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Deletion mapping of moloney type C virus: polypeptide and nucleic acid expression in different transforming virus isolates
Published in Journal of Virology (01-05-1976)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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