Search Results - "Anisimova, Aleksandra"

Multifaceted deregulation of gene expression and protein synthesis with age by Anisimova, Aleksandra S., Meerson, Mark B., Gerashchenko, Maxim V., Kulakovskiy, Ivan V., Dmitriev, Sergey E., Gladyshev, Vadim N.

“…Protein synthesis represents a major metabolic activity of the cell. However, how it is affected by aging and how this in turn impacts cell function remains…”
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Optimized infrared photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (IR-PAR-CLIP) protocol identifies novel IGF2BP3-interacting RNAs in colon cancer cells by Anisimova, Aleksandra S, Karagöz, G Elif

“…The conserved family of RNA-binding proteins (RBPs), IGF2BPs, plays an essential role in posttranscriptional regulation controlling mRNA stability,…”
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Protein synthesis and quality control in aging by Anisimova, Aleksandra S, Alexandrov, Alexander I, Makarova, Nadezhda E, Gladyshev, Vadim N, Dmitriev, Sergey E

“…Aging is characterized by the accumulation of damage and other deleterious changes, leading to the loss of functionality and fitness. Age-related changes occur…”
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IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism by Hornegger, Harald, Anisimova, Aleksandra S., Muratovic, Adnan, Bourgeois, Benjamin, Spinetti, Elena, Niedermoser, Isabell, Covino, Roberto, Madl, Tobias, Karagöz, G. Elif

“…The insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) is a conserved RNA-binding protein that regulates RNA stability, localization and…”
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svist4get: a simple visualization tool for genomic tracks from sequencing experiments by Egorov, Artyom A, Sakharova, Ekaterina A, Anisimova, Aleksandra S, Dmitriev, Sergey E, Gladyshev, Vadim N, Kulakovskiy, Ivan V

“…High-throughput sequencing often provides a foundation for experimental analyses in the life sciences. For many such methods, an intermediate layer of…”
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Tma64/eIF2D, Tma20/MCT-1, and Tma22/DENR Recycle Post-termination 40S Subunits In Vivo by Young, David J., Makeeva, Desislava S., Zhang, Fan, Anisimova, Aleksandra S., Stolboushkina, Elena A., Ghobakhlou, Fardin, Shatsky, Ivan N., Dmitriev, Sergey E., Hinnebusch, Alan G., Guydosh, Nicholas R.

“…The recycling of ribosomal subunits after translation termination is critical for efficient gene expression. Tma64 (eIF2D), Tma20 (MCT-1), and Tma22 (DENR)…”
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Human Tissues Exhibit Diverse Composition of Translation Machinery by Anisimova, Aleksandra S, Kolyupanova, Natalia M, Makarova, Nadezhda E, Egorov, Artyom A, Kulakovskiy, Ivan V, Dmitriev, Sergey E

“…While protein synthesis is vital for the majority of cell types of the human body, diversely differentiated cells require specific translation regulation. This…”
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A novel uORF-based regulatory mechanism controls translation of the human MDM2 and eIF2D mRNAs during stress by Akulich, Kseniya A., Sinitcyn, Pavel G., Makeeva, Desislava S., Andreev, Dmitry E., Terenin, Ilya M., Anisimova, Aleksandra S., Shatsky, Ivan N., Dmitriev, Sergey E.

“…Short upstream open reading frames (uORFs) are the most prevalent cis-acting regulatory elements in the mammalian transcriptome which can orchestrate mRNA…”
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Late Diagnosis of POMC Deficiency and in vitro evidence of residual translation from allele with c.-11C>A mutation by Anisimova, Aleksandra S, Rubtsov, Petr M, Akulich, Kseniya A, Dmitriev, Sergey E, Frolova, Elena, Tiulpakov, Anatoly

“…Context:Loss-of-function mutations in the POMC gene are associated with the syndrome of adrenal insufficiency, obesity and red hair. We describe here a case of…”
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Four translation initiation pathways employed by the leaderless mRNA in eukaryotes by Akulich, Kseniya A., Andreev, Dmitry E., Terenin, Ilya M., Smirnova, Victoria V., Anisimova, Aleksandra S., Makeeva, Desislava S., Arkhipova, Valentina I., Stolboushkina, Elena A., Garber, Maria B., Prokofjeva, Maria M., Spirin, Pavel V., Prassolov, Vladimir S., Shatsky, Ivan N., Dmitriev, Sergey E.

“…mRNAs lacking 5′ untranslated regions (leaderless mRNAs) are molecular relics of an ancient translation initiation pathway. Nevertheless, they still represent…”
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Translatome and transcriptome analysis of TMA20 (MCT-1) and TMA64 (eIF2D) knockout yeast strains by Makeeva, Desislava S., Lando, Andrey S., Anisimova, Aleksandra, Egorov, Artyom A., Logacheva, Maria D., Penin, Alexey A., Andreev, Dmitry E., Sinitcyn, Pavel G., Terenin, Ilya M., Shatsky, Ivan N., Kulakovskiy, Ivan V., Dmitriev, Sergey E.

“…TMA20 (MCT-1), TMA22 (DENR) and TMA64 (eIF2D) are eukaryotic translation factors involved in ribosome recycling and re-initiation. They operate with P-site…”
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Peculiarities of hemostasis in patients with COVID-19 by Kalinskaya, Anna I., Dukhin, Oleg A., Molodtsov, Ivan A., Anisimova, Aleksandra S., Sokorev, Denis A., Elizarova, Antonina K., Sapozhnikova, Olga A., Glebova, Kseniya A., Shakhidzhanov, Soslan S., Spiridonov, Ilia S., Ataullakhanov, Fazly I., Shpektor, Alexander V., Vasilieva, Elena Yu

“…Aim. Analysis of the dynamics of different stages of clot formation and its lysis in patients with different COVID-19 severity. Materials and methods. We…”
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Tma64 (eIF2D), Tma20 (MCT-1), and Tma22 (DENR) recycle post-termination 40S subunits in vivo by Young, David J., Makeeva, Desislava S., Zhang, Fan, Anisimova, Aleksandra S., Stolboushkina, Elena A., Ghobakhlou, Fardin, Shatsky, Ivan N., Dmitriev, Sergey E., Hinnebusch, Alan G., Guydosh, Nicholas R.

“…The recycling of ribosomal subunits after translation termination is critical for efficient gene expression. Tma64 (eIF2D), Tma20 (MCT-1), and Tma22 (DENR)…”
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Genesis and Development of Idyll Genre Theory in Germany in the First Half of the 18th Century (from I. H. Gushed to M. Mendelssohn) by A. N. Anisimova

“…The features of formation of idyll genre theory in Germany in the first half of the 18th century in the works of I. H. Gushed, S. Gessner, I. A. Schlegel and…”
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