Search Results - "Anil, Seegehalli M"
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Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages
Published in Scientific reports (14-01-2021)“…Cannabis sativa is widely used for medical purposes and has anti-inflammatory activity. This study intended to examine the anti-inflammatory activity of…”
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Cannabis-Derived Compounds Cannabichromene and Δ9-Tetrahydrocannabinol Interact and Exhibit Cytotoxic Activity against Urothelial Cell Carcinoma Correlated with Inhibition of Cell Migration and Cytoskeleton Organization
Published in Molecules (Basel, Switzerland) (17-01-2021)“…contains more than 500 constituents, yet the anticancer properties of the vast majority of cannabis compounds remains unknown. We aimed to identify cannabis…”
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Medical Cannabis Activity Against Inflammation: Active Compounds and Modes of Action
Published in Frontiers in pharmacology (09-05-2022)“…Inflammation often develops from acute, chronic, or auto-inflammatory disorders that can lead to compromised organ function. Cannabis ( ) has been used to…”
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Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway
Published in Molecules (Basel, Switzerland) (01-11-2022)“…Ovarian cancer (OC) is the single most lethal gynecologic malignancy. Cannabis sativa is used to treat various medical conditions, and is cytotoxic to a…”
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Integrated transcriptome and cell phenotype analysis suggest involvement of PARP1 cleavage, Hippo/Wnt, TGF-β and MAPK signaling pathways in ovarian cancer cells response to cannabis and PARP1 inhibitor treatment
Published in Frontiers in genetics (2024)“…is utilized mainly for palliative care worldwide. Ovarian cancer (OC) is a lethal gynecologic cancer. A particular cannabis extract fraction ('F7') and the…”
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Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models
Published in Pharmaceuticals (Basel, Switzerland) (01-12-2022)“…Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD],…”
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A sequential one-pot tandem approach for the synthesis of 4-tosyl-5-aryloxazoles from carboxylic acids
Published in Journal of chemical sciences (Bangalore, India) (01-11-2018)“…An efficient method for the synthesis of 4-tosyl-5-aryloxazoles directly from aromatic carboxylic acids has been reported. The method involves the conversion…”
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The reaction of arylmethyl isocyanides and arylmethylamines with xanthate esters: a facile and unexpected synthesis of carbamothioates
Published in Beilstein journal of organic chemistry (03-02-2020)“…An unexpected formation of carbamothioates by a sodium hydride-mediated reaction of arylmethyl isocyanides with xanthate esters in DMF is reported. The…”
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Synthesis of new coumarin tethered isoxazolines as potential anticancer agents
Published in Bioorganic & medicinal chemistry letters (15-12-2018)“…[Display omitted] •A novel series of new coumarin tethered isoxazolines were synthesized via 1,3-cyclo addition reaction.•Compound 7c is active against human…”
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Specific Compositions of Cannabis sativa Compounds Have Cytotoxic Activity and Inhibit Motility and Colony Formation of Human Glioblastoma Cells In Vitro
Published in Cancers (05-04-2021)“…Glioblastoma multiforme (GBM) is the most lethal subtype of glioma. is used for the treatment of various medical conditions. Around 150 phytocannabinoids have…”
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Base Induced Condensation of Malononitrile with Erlenmeyer Azlactones: An Unexpected Synthesis of Multi-Substituted Δ 2 -Pyrrolines and Their Cytotoxicity
Published in Chemistry & biodiversity (01-05-2020)“…An efficient, metal free approach to synthesize multi-substituted Δ -pyrroline derivatives by mild base catalyzed cyclocondensation of malononitrile with…”
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Base Induced Condensation of Malononitrile with Erlenmeyer Azlactones: An Unexpected Synthesis of Multi‐Substituted Δ2‐Pyrrolines and Their Cytotoxicity
Published in Chemistry & biodiversity (01-05-2020)“…An efficient, metal free approach to synthesize multi‐substituted Δ2‐pyrroline derivatives by mild base catalyzed cyclocondensation of malononitrile with…”
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Aqueous Chloroplatinic Acid: A Green, Chemoselective and Reusable Catalyst for the Deprotection of Acetals, Ketals, Dioxolanes and Oxathiolanes
Published in ChemistrySelect (Weinheim) (21-02-2018)“…Aqueous chloroplatinic acid (H2PtCl6) as an effective catalyst for the deprotection of acetals, ketals, 1,3‐dioxolanes and 1,3‐oxathiolanes to the…”
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Advanced VLS growth of gold encrusted silicon nanowires Mediated by porous Aluminium Oxide template
Published in Vacuum (01-03-2021)“…A highly efficient technique for the generation of dense and homogeneous Au-nanodroplets using Anodic Aluminium Oxide template (AAO) for the fabrication of…”
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