Search Results - "Anikina, Lada V."

Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential by Nevskaya, Alisa A, Anikina, Lada V, Purgatorio, Rosa, Catto, Marco, Nicolotti, Orazio, de Candia, Modesto, Pisani, Leonardo, Borisova, Tatiana N, Miftyakhova, Almira R, Varlamov, Aleksey V, Nevskaya, Elena Yu, Borisov, Roman S, Voskressensky, Leonid G, Altomare, Cosimo D

“…Marine alkaloids belonging to the lamellarins family, which incorporate a 5,6-dihydro-1-phenylpyrrolo[2,1- ]isoquinoline (DHPPIQ) moiety, possess various…”
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Nature-Inspired 1-Phenylpyrrolo[2,1- a ]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance by Nevskaya, Alisa A, Purgatorio, Rosa, Borisova, Tatiana N, Varlamov, Alexey V, Anikina, Lada V, Obydennik, Arina Yu, Nevskaya, Elena Yu, Niso, Mauro, Colabufo, Nicola A, Carrieri, Antonio, Catto, Marco, de Candia, Modesto, Voskressensky, Leonid G, Altomare, Cosimo D

“…Previous studies have shown that some lamellarin-resembling annelated azaheterocyclic carbaldehydes and related imino adducts, sharing the…”
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Synthesis and antitumor activity of daunorubicin conjugates with of 3,4-methylendioxybenzaldehyde by Moiseeva, Aleksandra A., Artyushin, Oleg I., Anikina, Lada V., Brel, Valery K.

“…[Display omitted] The design of hybrid (chimeric) molecules containing two different pharmacophores connected via a spacer (linker) is a promising approach to…”
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Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors by Lozinskaya, Natalia A., Babkov, Denis A., Zaryanova, Ekaterina V., Bezsonova, Elena N., Efremov, Alexander M., Tsymlyakov, Michael D., Anikina, Lada V., Zakharyascheva, Olga Yu, Borisov, Alexander V., Perfilova, Valentina N., Tyurenkov, Ivan N., Proskurnina, Marina V., Spasov, Alexander A.

“…[Display omitted] Glycogen synthase kinase 3β (GSK-3β) is a widely investigated molecular target for numerous diseases including Alzheimer’s disease, cancer,…”
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Synthesis and biological evaluation of new substituted thioglycolurils, their analogues and derivatives by Gazieva, Galina A., Anikina, Lada V., Nechaeva, Tatyana V., Pukhov, Sergey A., Karpova, Tatyana B., Popkov, Sergey V., Nelyubina, Yulia V., Kolotyrkina, Natalya G., Kravchenko, Angelina N.

“…A novel series of substituted N-aminothioglycolurils was synthesized by tandem hydrazone formation – ring contraction reaction of…”
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2,4,5-Tris(alkoxyaryl)imidazoline derivatives as potent scaffold for novel p53-MDM2 interaction inhibitors: Design, synthesis, and biological evaluation by Bazanov, Daniil R., Pervushin, Nikolay V., Savitskaya, Victoria Yu, Anikina, Lada V., Proskurnina, Marina V., Lozinskaya, Natalia A., Kopeina, Gelina S.

“…[Display omitted] Imidazoline-based small molecule inhibitors of p53-MDM2 interaction intended for the treatment of p53 wild-type tumors are the promising…”
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N-Phosphorylation of daunorubicin—synthetic approaches and antiproliferative properties of the products by Moiseeva, Aleksandra A., Artyushin, Oleg I., Anikina, Lada V., Klemenkova, Zinaida S., Brel, Valery K.

“…Synthetic approaches to daunorubicin derivatives containing azide and propargyl fragments were developed. A series of phosphonate and bisphosphonate…”
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Simple methods of modification of daunorubicin on the daunosamine nitrogen atom by Brel, Valery K., Moiseeva, Aleksandra A., Artyushin, Oleg I., Anikina, Lada V., Klemenkova, Zinaida S.

“…Modification of daunorubicin on its NH 2 moiety is a well-established synthetic approach to obtain novel derivatives of this compound. Moreover, the…”
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Synthesis, structural characterization and cytotoxic activity of heterocyclic compounds containing the furoxan ring by Kulikov, Alexander S., Larin, Alexander A., Fershtat, Leonid L., Anikina, Lada V., Pukhov, Sergey A., Klochkov, Sergey G., Struchkova, Marina I., Romanova, Anna A., Ananyev, Ivan V., Makhova, Nina N.

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The influence of substituents on the reactivity and cytotoxicity of imidazothiazolotriazinones by Gazieva, Galina A., Izmest’ev, Alexei N., Anikina, Lada V., Pukhov, Sergey A., Meshchaneva, Marina E., Khakimov, Dmitry V., Kolotyrkina, Natalya G., Kravchenko, Angelina N.

“…A series of tetrahydroimidazo[4,5- e ]thiazolo[3,2- b ]-1,2,4-triazine-2,7(1 H , 6 H )-diones were synthesized via the reaction of imidazotriazinethiones and…”
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Substituted N-aminothioglycolurils containing thiosemicarbazone moiety and their cytotoxic activity in vitro by Gazieva, Galina A., Anikina, Lada V., Pukhov, Sergei A., Karpova, Tatyana B., Nelyubina, Yulia V., Kravchenko, Angelina N.

“…A library of hybrid molecules bearing thioglycoluril and (hetero)aromatic aldehyde thiosemicarbazone moieties was synthesized via a tandem hydrazone…”
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Synthesis, transformation and biological evaluation of 2,3-secotriterpene acetylhydrazones and their derivatives by Grishko, Victoria V., Tolmacheva, Irina A., Galaiko, Natalia V., Pereslavceva, Anastasia V., Anikina, Lada V., Volkova, Larisa V., Bachmetyev, Boris A., Slepukhin, Pavel A.

“…It has been previously shown that semi-synthetic A-secotriterpene acetylhydrazones of 1-cyano-28-methoxy-28-oxo-2,3-seco-2-norlup-20(29)-en-3-al and…”
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1,5-Diaryl-3-oxo-1,4-pentadienes based on (4-oxopiperidin-1-yl)(aryl)methyl phosphonate scaffold: synthesis and antitumor properties by Makarov, Mikhail V., Rybalkina, Ekaterina Yu, Anikina, Lada V., Pukhov, Sergey A., Klochkov, Sergey G., Mischenko, Denis V., Neganova, Margarita E., Khrustalev, Victor N., Klemenkova, Zinaida S., Brel, Valery K.

“…Novel 3,5-bis(arylidene)-4-piperidones modified with diethyl[(aryl)methyl]phosphonate moiety attached to the piperidone nitrogen atom have been synthesized by…”
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Synthesis and cytotoxicity of novel 1-arylindolizines and 1-arylpyrrolo[2,1-a]isoquinolines by Nevskaya, Alisa A., Miftyakhova, Almira R., Anikina, Lada V., Borisova, Tatiana N., Varlamov, Aleksey V., Voskressensky, Leonid G.

“…[Display omitted] An efficient approach to the synthesis of indolizines and pyrrolo[2,1-a]isoquinolines based on a domino reaction is described. The reactivity…”
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Preparative synthesis and pharmacological activity of Albicar racemate and enantiomers by Anikina, Lada V., Vikharev, Yuri B., Baranov, Vladimir V., Malyshev, Oleg R., Kravchenko, Angelina N.

“…[Display omitted] Racemic Albicar (2,6-diethyl-4,8-dimethylglycoluril) has been synthesized and resolved into enantiomers on a preparative scale by chiral…”
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Hydrogen bonding in triols on the triphenylphosphine oxide platform in crystal and solution: Effect of linker length by Baulina, Tat’yana V., Pasechnik, Margarita P., Kudryavtsev, Igor Yu, Bykhovskaya, Olga V., Sukat, Georgii Ya, Smol’yakov, Alexander F., Anikina, Lada V., Brel, Valery K.

“…The structure of tripodal phosphoryl alkanols [2-HO(CH2)nOC6H4]3P = O (n = 2, 3, 4) have been studied in crystal and solution by X-ray diffraction and FTIR…”
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Regioselective synthesis, structural diversification and cytotoxic activity of (thiazol-4-yl)furoxans by Kulikov, Alexander S., Epishina, Margarita A., Churakov, Artem I., Anikina, Lada V., Fershtat, Leonid L., Makhova, Nina N.

“…[Display omitted] The effective and regioselective synthesis of new (2-hydrazinylthiazol-4-yl)furoxan hydrobromides based on the condensation of…”
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New Conjugates of Daunorubicin with Sesquiterpene Lactones and Their Biological Activity by Pukhov, Sergey A., Semakov, Alexey V., Globa, Anastasiya A., Anikina, Lada V., Afanasyeva, Svetlana V., Yandulova, Ekaterina Y., Aleksandrova, Yulia R., Neganova, Margarita E., Klochkov, Sergey G.

“…New conjugates of daunorubicin with sesquiterpene lactones at the 3′‐amino group of anthracycline were synthesized and their effect on the viability of cell…”
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Target synthesis of bioactive thioglycolurils, based on QSAR predictions by Gazieva, Galina A., Vikharev, Yurii B., Anikina, Lada V., Karpova, Tatyana B., Kravchenko, Angelina N., Permyakov, Evgenii A., Svitanko, Igor V.

“…Target synthesis of substituted thioglycolurils possessing sedative activity predicted by preliminary 3D-QSAR simulation of bioactive structures has been…”
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