Search Results - "Anikin, Ivan V."

Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo by Anisimov, Vladimir N., Egormin, Peter A., Piskunova, Tatiana S., Popovich, Irina G., Tyndyk, Margarita L., Yurova, Maria N., Zabezhinski, Mark A., Anikin, Ivan V., Karkach, Arseniy S., Romanyukha, Alexey A.

“…Population studies have shown that treatment with the antidiabetic biguanide metformin significantly reduced cancer risk. In our animal studies, metformin…”
Get full text

Assessment of antitumor activity of BP-C1, a platinum-based anticancer agent with a lignin-derived polymeric ligand, in autochthonous induced and spontaneous carcinogenesis rodent models by Fedoros, Elena I., Tyndyk, Margarita L., Popovich, Irina G., Anikin, Ivan V., Yurova, Maria N., Gubareva, Ekaterina A., Pigarev, Sergey E., Panchenko, Andrey V., Solovyev, Nikolay D., Anisimov, Vladimir N.

“…A standard approach to study the anticancer activity of novel drugs is their testing in animals with inoculated tumors, which has some limitations. An…”
Get full text

Central and Peripheral Effects of Insulin/IGF-1 Signaling in Aging and Cancer: Antidiabetic Drugs as Geroprotectors and Anticarcinogens by ANISIMOV, VLADIMIR N., BERSTEIN, LEV M., POPOVICH, IRINA G., ZABEZHINSKI, MARK A., EGORMIN, PETER A., TYNDYK, MARGARITA L., ANIKIN, IVAN V., SEMENCHENKO, ANNA V., YASHIN, ANATOLI I.

“…Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors both in aging and in the development of cancer…”
Get full text

Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice by Anisimov, Vladimir N, Popovich, Irina G, Zabezhinski, Mark A, Yurova, Maria N, Tyndyk, Margarita L, Anikin, Ivan V, Egormin, Peter A, Baldueva, Irina A, Fedoros, Elena I, Pigarev, Sergey E, Panchenko, Andrey V

“…Effects of long-term application of novel polyphenolic composition BP-C3, containing polyphenolic benzenepolycarboxylic acids, vitamins and minerals on some…”
Get full text

Rodent models for the preclinical evaluation of drugs suitable for pharmacological intervention in aging by Anisimov, Vladimir N, Zabezhinski, Mark A, Popovich, Irina G, Pliss, Gennady B, Bespalov, Vladimir G, Alexandrov, Valeri A, Stukov, Alexander N, Anikin, Ivan V, Alimova, Irina N, Egormin, Peter А, Panchenko, Andrey V, Piskunova, Tatiana S, Semenchenko, Anna V, Tyndyk, Margarita L, Yurova, Maria N

“…There is a growing scientific and public interest in the development of new antiaging drugs for the purposes of extending mean and/or maximum life span,…”
Get more information

Insulin in aging and cancer: antidiabetic drug diabenol as geroprotector and anticarcinogen by Popovich, Irina G., Zabezhinski, Mark A., Egormin, Peter A., Tyndyk, Margarita L., Anikin, Ivan V., Spasov, Alexander A., Semenchenko, Anna V., Yashin, Anatoly I., Anisimov, Vladimir N.

“…The effects of new antidiabetic drug Diabenol ® (9-β-diethylaminoethyl-2,3-dihydroimidazo-(1,2-α)benzimidazol dihydrochloride) on life span and spontaneous…”
Get full text

Effects of phentermine and phenformin on biomarkers of aging in rats by Anisimov, Vladimir N, Ukraintseva, Svetlana V, Anikin, Ivan V, Popovich, Irina G, Zabezhinski, Mark A, Bertsein, Lev M, Arutjunyan, Alexander V, Ingram, Donald K, Lane, Mark A, Roth, George S

“…Caloric restriction (CR) is the only treatment known to substantially prolong both average and maximal life span in experimental animals. Interventions that…”
Get more information