Search Results - "Anido, Judit"

Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation by Anido, Judit, Scaltriti, Maurizio, Bech Serra, Joan Josep, Josefat, Belén Santiago, Rojo Todo, Federico, Baselga, José, Arribas, Joaquín

“…The overactivation of the HERs, a family of tyrosine kinase receptors, leads to the development of cancer. Although the canonical view contemplates HER…”
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ZD1839, a Specific Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor, Induces the Formation of Inactive EGFR/HER2 and EGFR/HER3 Heterodimers and Prevents Heregulin Signaling in HER2-overexpressing Breast Cancer Cells by ANIDO, Judit, MATAR, Pablo, ALBANELL, Joan, GUZMAN, Marta, ROJO, Federico, ARRIBAS, Joaquin, AVERBUCH, Steve, BASELGA, Jose

“…Purpose: ZD1839 is a tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR) that has shown clinical activity against EGFR-expressing tumors…”
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TGF-β Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma by Anido, Judit, Sáez-Borderías, Andrea, Gonzàlez-Juncà, Alba, Rodón, Laura, Folch, Gerard, Carmona, Maria A, Prieto-Sánchez, Rosa M, Barba, Ignasi, Martínez-Sáez, Elena, Prudkin, Ludmila, Cuartas, Isabel, Raventós, Carolina, Martínez-Ricarte, Francisco, Poca, M Antonia, García-Dorado, David, Lahn, Michael M, Yingling, Jonathan M, Rodón, Jordi, Sahuquillo, Juan, Baselga, José, Seoane, Joan

“…Glioma-initiating cells (GICs), also called glioma stem cells, are responsible for tumor initiation, relapse, and therapeutic resistance. Here, we show that…”
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Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment by Hallett, Robin M, Bonfill-Teixidor, Ester, Iurlaro, Raffaella, Arias, Alexandra, Raman, Swetha, Bayliss, Peter, Egorova, Olga, Neva-Alejo, Almudena, McGray, Aj Robert, Lau, Esther, Bosch, Alexandre, Beilschmidt, Melissa, Maetzel, Dorothea, Fransson, Johan, Huber-Ruano, Isabel, Anido, Judit, Julien, Jean-Philippe, Giblin, Patricia, Seoane, Joan

“…Leukemia inhibitory factor (LIF) is a multifunctional cytokine with numerous reported roles in cancer and is thought to drive tumor development and…”
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TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma by Peñuelas, Silvia, Anido, Judit, Prieto-Sánchez, Rosa M., Folch, Gerard, Barba, Ignasi, Cuartas, Isabel, García-Dorado, David, Poca, M. Antonia, Sahuquillo, Juan, Baselga, Jose, Seoane, Joan

“…Glioma-initiating cells (GICs) are responsible for the initiation and recurrence of gliomas. Here, we identify a molecular mechanism that regulates the…”
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Expression of p95HER2, a Truncated Form of the HER2 Receptor, and Response to Anti-HER2 Therapies in Breast Cancer by Scaltriti, Maurizio, Rojo, Federico, Ocaña, Alberto, Anido, Judit, Guzman, Marta, Cortes, Javier, Di Cosimo, Serena, Matias-Guiu, Xavier, Ramon y Cajal, Santiago, Arribas, Joaquin, Baselga, José

“…Background Women with HER2–overexpressing breast cancers have poor prognosis, and many are resistant to the HER2 monoclonal antibody trastuzumab. A subgroup of…”
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Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment by Hallett, Robin M., Bonfill-Teixidor, Ester, Iurlaro, Raffaella, Arias, Alexandra, Raman, Swetha, Bayliss, Peter, Egorova, Olga, Neva-Alejo, Almudena, McGray, AJ Robert, Lau, Esther, Bosch, Alexandre, Beilschmidt, Melissa, Maetzel, Dorothea, Fransson, Johan, Huber-Ruano, Isabel, Anido, Judit, Julien, Jean-Philippe, Giblin, Patricia, Seoane, Joan

“…Abstract Purpose:Leukemia inhibitory factor (LIF) is a multifunctional cytokine with numerous reported roles in cancer and is thought to drive tumor…”
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Abstract CT014: Initial results from the Phase I study of MSC-1, a humanized anti-LIF monoclonal antibody, in patients with advanced solid tumors by Schram, Alison, Spreafico, Anna, Oliva, Marc, Brana, Irene, Garralda, Elena, Lakhani, Nehal, Hoff, Daniel Von, Borazanci, Erkut, Pandya, Naimish, Hoffman, Kimberly, Hallett, Robin, Giblin, Patricia, Anido, Judit, Kelly, Adrianne, Wasserman, Robert, Seoane, Joan, Siu, Lillian, Hyman, David M., Tabernero, Josep

“…Abstract Background: Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine involved in many physiological and pathological processes. LIF is highly…”
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Abstract CT147: Phase 1 dose escalation of MSC-1, a humanized anti-LIF monoclonal antibody, in patients with advanced solid tumors by Schram, Alison, Borazanci, Erkut, Brana, Irene, Villar, Maria Vieito, Garralda, Elena, Spreafico, Anna, Oliva, Marc, Lakhani, Nehal, Wasserman, Robert, Hoffmann, Kimberly, Hallett, Robin, Anido, Judit, Maetzel, Dorotea, Giblin, Patricia, Moran, Enda, Kelly, Adrianne, Seoane, Joan, Von Hoff, Daniel D., Siu, Lillian, Tabernero, Josep

“…Abstract Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine, which is highly expressed in a subset of tumors and correlates with poor prognosis. LIF is…”
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Abstract LB-B34: LIF as a novel cancer immunotherapy target: modulating the tumor microenvironment with MSC-1, a humanized anti-LIF monoclonal antibody by Magram, Jeanne, Pandya, Naimish, Hoffman, Kimberly, Hallett, Robin, Giblin, Patricia, Sinclair, Angus, Anido, Judit, Ruano, Isabel Huber, Sala, Ada, Pascual, Monica, Chiganças, Vanessa, Wasserman, Robert, Seoane, Joan

“…Abstract Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine involved in many physiological and pathological processes. LIF is highly expressed in a…”
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Abstract 1751: MSC-1 is a first-in-class humanized monoclonal antibody that modulates the tumor microenvironment by inhibiting a novel cancer immunotherapy target, LIF by Sinclair, Angus, Hallett, Robin, Giblin, Patricia, Huber-Ruano, Isabel, Anido, Judit, Pandya, Naimish, Hoffman, Kimberly, Sala, Ada, Pascual, Monica, Chigancas, Vanessa, Raman, Swetha, Fransson, Johan, Julien, Jean-Philippe, Wasserman, Robert, Magram, Jeanne, Seoane, Joan

“…Abstract Leukemia Inhibitory Factor (LIF) is a member of the IL-6 family of cytokines and is involved in many physiological and pathological processes…”
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A phase 1 study of MSC-1, a humanized anti-LIF monoclonal antibody, in patients with advanced solid tumors by Hyman, David Michael, Brana, Irene, Spreafico, Anna, Schram, Alison M., Pandya, Naimish B., Hoffman, Kimberly, Hallet, Robin, Giblin, Patricia, Anido, Judit, Ruano, Isabel Huber, Wasserman, Robert, Magram, Jeanne, Siu, Lillian L., Tabernero, Josep, Seoane, Joan, Baselga, Jose

“…Abstract only…”
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Activated extracellular signal-regulated kinases : Association with epidermal growth factor receptor/transforming growth factor α expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments by ALBANELL, Joan, CODONY-SERVAT, Jordi, MENDELSOHN, John, BASELGA, José, ROJO, Federico, DEL CAMPO, José M, SAULEDA, Silvia, ANIDO, Judit, RASPALL, Guillermo, GIRALT, Jordi, ROSELLO, José, NICHOLSON, Robert I

“…The expression of the activated mitogen-activated kinases/extracellular signal-regulated kinases (ERKs) ERK1 and ERK2 was characterized in 101 humanhead and…”
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Noncyclam Tetraamines Inhibit CXC Chemokine Receptor Type 4 and Target Glioma-Initiating Cells by Ros-Blanco, Laia, Anido, Judit, Bosser, Ramon, Esté, José, Clotet, Bonaventura, Kosoy, Ana, Ruíz-Ávila, Luis, Teixidó, Jordi, Seoane, Joan, Borrell, José I

“…The three stereoisomers of the noncyclam compound 1 (1(R,R), 1(S,S), and the meso form 1(S,R)) and their corresponding tetrahydrochlorides 11 were prepared…”
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TGF-β Receptor Inhibitors Target the CD44 high/Id1 high Glioma-Initiating Cell Population in Human Glioblastoma by Anido, Judit, Sáez-Borderías, Andrea, Gonzàlez-Juncà, Alba, Rodón, Laura, Folch, Gerard, Carmona, Maria A., Prieto-Sánchez, Rosa M., Barba, Ignasi, Martínez-Sáez, Elena, Prudkin, Ludmila, Cuartas, Isabel, Raventós, Carolina, Martínez-Ricarte, Francisco, Poca, M. Antonia, García-Dorado, David, Lahn, Michael M., Yingling, Jonathan M., Rodón, Jordi, Sahuquillo, Juan, Baselga, José, Seoane, Joan

“…Glioma-initiating cells (GICs), also called glioma stem cells, are responsible for tumor initiation, relapse, and therapeutic resistance. Here, we show that…”
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TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma by Anido, Judit, Sáez-Borderías, Andrea, Gonzàlez-Juncà, Alba, Rodón, Laura, Folch, Gerard, Carmona, Maria A., Prieto-Sánchez, Rosa M., Barba, Ignasi, Martínez-Sáez, Elena, Prudkin, Ludmila, Cuartas, Isabel, Raventós, Carolina, Martínez-Ricarte, Francisco, Poca, M. Antonia, García-Dorado, David, Lahn, Michael M., Yingling, Jonathan M., Rodón, Jordi, Sahuquillo, Juan, Baselga, José, Seoane, Joan

“…Glioma-initiating cells (GICs), also called glioma stem cells, are responsible for tumor initiation, relapse, and therapeutic resistance. Here, we show that…”
Get full text