Search Results - "Anh, T. Le"

TRKing down an old oncogene in a new era of targeted therapy by Vaishnavi, Aria, Le, Anh T, Doebele, Robert C

“…The use of high-throughput next-generation sequencing techniques in multiple tumor types during the last few years has identified NTRK1, 2, and 3 gene…”
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Lignin degradation by microorganisms: A review by Atiwesh, Ghada, Parrish, Christopher C., Banoub, Joseph, Le, Tuyet‐Anh T.

“…Lignin is an abundant plant‐based biopolymer that has found applications in a variety of industries from construction to bioethanol production. This…”
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Environmental impact of bioplastic use: A review by Atiwesh, Ghada, Mikhael, Abanoub, Parrish, Christopher C., Banoub, Joseph, Le, Tuyet-Anh T.

“…Throughout their lifecycle, petroleum-based plastics are associated with many environmental problems, including greenhouse gas emissions, persistence in marine…”
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Policy Responses to the COVID-19 Pandemic in Vietnam by Le, Tuyet-Anh T, Vodden, Kelly, Wu, Jianghua, Atiwesh, Ghada

“…The COVID-19 pandemic has become one of the most serious health crises in human history, spreading rapidly across the globe from January 2020 to the present…”
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Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer by Robichaux, Jacqulyne P., Elamin, Yasir Y., Tan, Zhi, Carter, Brett W., Zhang, Shuxing, Liu, Shengwu, Li, Shuai, Chen, Ting, Poteete, Alissa, Estrada-Bernal, Adriana, Le, Anh T., Truini, Anna, Nilsson, Monique B., Sun, Huiying, Roarty, Emily, Goldberg, Sarah B., Brahmer, Julie R., Altan, Mehmet, Lu, Charles, Papadimitrakopoulou, Vassiliki, Politi, Katerina, Doebele, Robert C., Wong, Kwok-Kin, Heymach, John V.

“…Although most activating mutations of epidermal growth factor receptor (EGFR)-mutant non–small cell lung cancers (NSCLCs) are sensitive to available EGFR…”
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Comparison of Molecular Testing Modalities for Detection of ROS1 Rearrangements in a Cohort of Positive Patient Samples by Davies, Kurtis D, Le, Anh T, Sheren, Jamie, Nijmeh, Hala, Gowan, Katherine, Jones, Kenneth L, Varella-Garcia, Marileila, Aisner, Dara L, Doebele, Robert C

“…ROS1 gene fusions are a well-characterized class of oncogenic driver found in approximately 1% to 2% of NSCLC patients. ROS1-directed therapy in these patients…”
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Resistance Mechanisms to Targeted Therapies in ROS1 + and ALK + Non-small Cell Lung Cancer by McCoach, Caroline E, Le, Anh T, Gowan, Katherine, Jones, Kenneth, Schubert, Laura, Doak, Andrea, Estrada-Bernal, Adriana, Davies, Kurtis D, Merrick, Daniel T, Bunn, Jr, Paul A, Purcell, W Tom, Dziadziuszko, Rafal, Varella-Garcia, Marileila, Aisner, Dara L, Camidge, D Ross, Doebele, Robert C

“…Despite initial benefit from tyrosine kinase inhibitors (TKIs), patients with advanced non-small cell lung cancer (NSCLC) harboring (ALK ) and (ROS1 ) gene…”
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Clinical Utility of Cell-Free DNA for the Detection of ALK Fusions and Genomic Mechanisms of ALK Inhibitor Resistance in Non-Small Cell Lung Cancer by McCoach, Caroline E, Blakely, Collin M, Banks, Kimberly C, Levy, Benjamin, Chue, Ben M, Raymond, Victoria M, Le, Anh T, Lee, Christine E, Diaz, Joseph, Waqar, Saiama N, Purcell, William T, Aisner, Dara L, Davies, Kurtis D, Lanman, Richard B, Shaw, Alice T, Doebele, Robert C

“…Patients with advanced non-small cell lung cancer (NSCLC) whose tumors harbor anaplastic lymphoma kinase ( gene fusions benefit from treatment with ALK…”
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Identifying and Targeting ROS1 Gene Fusions in Non―Small Cell Lung Cancer by DAVIES, Kurtis D, LE, Anh T, ALLOISIO, Marco, SANTORO, Armando, ROSS CAMIDGE, D, VARELLA-GARCIA, Marileila, DOEBELE, Robert C, THEODORO, Mariana F, SKOKAN, Margaret C, AISNER, Dara L, BERGE, Eamon M, TERRACCIANO, Luigi M, CAPPUZZO, Federico, INCARBONE, Matteo, RONCALLI, Massimo

“…Oncogenic gene fusions involving the 3' region of ROS1 kinase have been identified in various human cancers. In this study, we sought to characterize ROS1…”
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Tarloxotinib Is a Hypoxia-Activated Pan-HER Kinase Inhibitor Active Against a Broad Range of HER-Family Oncogenes by Estrada-Bernal, Adriana, Le, Anh T, Doak, Andrea E, Tirunagaru, Vijaya G, Silva, Shevan, Bull, Matthew R, Smaill, Jeff B, Patterson, Adam V, Kim, Chul, Liu, Stephen V, Doebele, Robert C

“…Approved therapies for exon 20, mutations, and fusions are currently lacking for non-small cell lung cancer and other cancers. Tarloxotinib is a prodrug that…”
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An Activating KIT Mutation Induces Crizotinib Resistance in ROS1-Positive Lung Cancer by Dziadziuszko, Rafal, Le, Anh T, Wrona, Anna, Jassem, Jacek, Camidge, D Ross, Varella-Garcia, Marileila, Aisner, Dara L, Doebele, Robert C

“…Patients with non-small cell lung cancer (NSCLC) harboring ROS proto-oncogene 1, receptor tyrosine kinase gene (ROS1) chromosomal rearrangements benefit from…”
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Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer by Davies, Kurtis D, Mahale, Sakshi, Astling, David P, Aisner, Dara L, Le, Anh T, Hinz, Trista K, Vaishnavi, Aria, Bunn, Jr, Paul A, Heasley, Lynn E, Tan, Aik-Choon, Camidge, D Ross, Varella-Garcia, Marileila, Doebele, Robert C

“…The targeting of oncogenic 'driver' kinases with small molecule inhibitors has proven to be a highly effective therapeutic strategy in selected non-small cell…”
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Resistance to RET-Inhibition in RET-Rearranged NSCLC Is Mediated By Reactivation of RAS/MAPK Signaling by Nelson-Taylor, Sarah K, Le, Anh T, Yoo, Minjae, Schubert, Laura, Mishall, Katie M, Doak, Andrea, Varella-Garcia, Marileila, Tan, Aik-Choon, Doebele, Robert C

“…Oncogenic rearrangements in are present in 1%-2% of lung adenocarcinoma patients. Ponatinib is a multi-kinase inhibitor with low-nanomolar potency against the…”
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Household-Contact Investigation for Detection of Tuberculosis in Vietnam by Fox, Greg J, Nhung, Nguyen V, Sy, Dinh N, Hoa, Nghiem L.P, Anh, Le T.N, Anh, Nguyen T, Hoa, Nguyen B, Dung, Nguyen H, Buu, Tran N, Loi, Nguyen T, Nhung, Le T, Hung, Nguyen V, Lieu, Phan T, Cuong, Nguyen K, Cuong, Pham D, Bestrashniy, Jessica, Britton, Warwick J, Marks, Guy B

“…Tuberculosis continues to be a global health challenge. In this report, active case finding was more than twice as likely as standard passive case finding to…”
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EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases by Vaishnavi, Aria, Schubert, Laura, Rix, Uwe, Marek, Lindsay A, Le, Anh T, Keysar, Stephen B, Glogowska, Magdalena J, Smith, Matthew A, Kako, Severine, Sumi, Natalia J, Davies, Kurtis D, Ware, Kathryn E, Varella-Garcia, Marileila, Haura, Eric B, Jimeno, Antonio, Heasley, Lynn E, Aisner, Dara L, Doebele, Robert C

“…Oncogenic kinase fusions of , , , and act as drivers in human lung and other cancers. Residual tumor burden following treatment of ALK or ROS1 lung cancer…”
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Genotypic and Phenotypic Diversity of Endemic Golden Camellias Collected from the North of Vietnam by Van‐Anh Le, T., Mai Nga, T. P., Nhi Nguyen, P., Kieu‐Oanh Nguyen, T.

“…Golden Camellias have recently been used as a food, cosmetic, and traditional medicine in China and Vietnam. Forty‐two species have natural distribution in…”
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Investigating the determinants and process of destination management system (DMS) implementation by Le, Anh T. P, Kunasekaran, Puvaneswaran, Rasoolimanesh, S. Mostafa, AriRagavan, Neethiahnanthan, Thomas, Toney K

“…PurposeThis study aims to propose a comprehensive model to help understand factors influencing the intention to participate in a destination management system…”
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Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes by Harper, Angelica R., Le, Anh T., Mather, Timothy, Burgett, Anthony, Berry, William, Summers, Jody A.

“…[Display omitted] The retinaldehyde dehydrogenase (RALDH) enzymes, RALDH1, RALDH2, and RALDH3, catalyze the irreversible oxidation of retinaldehyde to…”
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Payments for ecosystem services programs: A global review of contributions towards sustainability by Le, Tuyet-Anh T., Vodden, Kelly, Wu, Jianghua, Bullock, Ryan, Sabau, Gabriela

“…Payments for ecosystem services programs (PESPs) are increasingly being adopted globally to enhance sustainability outcomes. There are also hundreds of studies…”
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High dose acetaminophen inhibits STAT3 and has free radical independent anti-cancer stem cell activity by Pingali, Pavani, Wu, Y. Jeffrey, Boothello, Rio, Sharon, Chetna, Li, Howard, Sistla, Srinivas, Sankaranarayanan, Nehru Viji, Desai, Umesh R., Le, Anh T., Doebele, Robert C., Muldoon, Leslie L., Patel, Bhaumik B., Neuwelt, Alexander

“…High-dose acetaminophen (AAP) with delayed rescue using n-acetylcysteine (NAC), the FDA-approved antidote to AAP overdose, has demonstrated promising antitumor…”
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