Search Results - "Angus, C"

Natural selection and Neanderthal extinction in a Malthusian economy by Chu, Angus C.

“…Why are Homo sapiens the only human species living on this planet? Homo sapiens have lived on this planet for about 300,000 years. During most of their…”
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Structural basis for protein phosphatase 1 regulation and specificity by Peti, Wolfgang, Nairn, Angus C, Page, Rebecca

“…The ubiquitous serine/threonine protein phosphatase 1 (PP1) regulates diverse, essential cellular processes such as cell cycle progression, protein synthesis,…”
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High sensitivity and interindividual variability in the response of the human circadian system to evening light by Phillips, Andrew J. K., Vidafar, Parisa, Burns, Angus C., McGlashan, Elise M., Anderson, Clare, Rajaratnam, Shantha M. W., Lockley, Steven W., Cain, Sean W.

“…Before the invention of electric lighting, humans were primarily exposed to intense (>300 lux) or dim (<30 lux) environmental light—stimuli at extreme ends of…”
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Impact of Cultured Neuron Models on α-Herpesvirus Latency Research by Wilson, Angus C.

“…A signature trait of neurotropic α-herpesviruses (α-HV) is their ability to establish stable non-productive infections of peripheral neurons termed latency…”
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Increased Sensitivity of the Circadian System to Light in Early/Mid-Puberty by Crowley, Stephanie J, Cain, Sean W, Burns, Angus C, Acebo, Christine, Carskadon, Mary A

“…Context: Late adolescence is marked by a delay in sleep timing, which is partly driven by a delay shift of the circadian timing system. This study examined…”
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Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations by Fleischmann, Carolin, Scherag, André, Adhikari, Neill K J, Hartog, Christiane S, Tsaganos, Thomas, Schlattmann, Peter, Angus, Derek C, Reinhart, Konrad

“…Reducing the global burden of sepsis, a recognized global health challenge, requires comprehensive data on the incidence and mortality on a global scale. To…”
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A cultured affair: HSV latency and reactivation in neurons by Wilson, Angus C, Mohr, Ian

“…After replicating in surface epithelia, herpes simplex virus type-1 (HSV-1) enters the axonal terminals of peripheral neurons. The viral genome translocates to…”
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cAMP regulation of protein phosphatases PP1 and PP2A in brain by Leslie, Shannon N., Nairn, Angus C.

“…Normal functioning of the brain is dependent upon a complex web of communication between numerous cell types. Within neuronal networks, the faithful…”
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A Randomized Trial of a Family-Support Intervention in Intensive Care Units by White, Douglas B, Angus, Derek C, Shields, Anne-Marie, Buddadhumaruk, Praewpannarai, Pidro, Caroline, Paner, Cynthia, Chaitin, Elizabeth, Chang, Chung-Chou H, Pike, Francis, Weissfeld, Lisa, Kahn, Jeremy M, Darby, Joseph M, Kowinsky, Amy, Martin, Susan, Arnold, Robert M

“…In a cluster-randomized trial conducted in five ICUs, a nurse-led family-support intervention did not affect surrogates’ scores for anxiety and depression 6…”
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Effects of patents versus R&D subsidies on income inequality by Chu, Angus C., Cozzi, Guido

“…This study explores the effects of patent protection and R&D subsidies on innovation and income inequality using a Schumpeterian growth model with…”
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Export-led takeoff in a Schumpeterian economy by Chu, Angus C., Peretto, Pietro, Xu, Rongxin

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Patent policy and economic growth: A survey by Chu, Angus C.

“…This survey provides a selective review of the literature on patent policy, innovation and economic growth. The patent system is a useful policy tool for…”
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An isotopically-labelled temporal mass spectrometry imaging data analysis workflow to reveal glucose spatial metabolism patterns in bovine lens tissue by Shi, Dingchang, Grey, Angus C., Guo, George

“…Application of stable isotopically labelled (SIL) molecules in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI-MSI) over a series…”
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Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen by Depledge, Daniel P., Srinivas, Kalanghad Puthankalam, Sadaoka, Tomohiko, Bready, Devin, Mori, Yasuko, Placantonakis, Dimitris G., Mohr, Ian, Wilson, Angus C.

“…Characterizing complex viral transcriptomes by conventional RNA sequencing approaches is complicated by high gene density, overlapping reading frames, and…”
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High-performance neuroprosthetic control by an individual with tetraplegia by Collinger, Jennifer L, PhD, Wodlinger, Brian, PhD, Downey, John E, BS, Wang, Wei, PhD, Tyler-Kabara, Elizabeth C, MD, Weber, Douglas J, PhD, McMorland, Angus JC, PhD, Velliste, Meel, PhD, Boninger, Michael L, Prof, Schwartz, Andrew B, Prof

“…Summary Background Paralysis or amputation of an arm results in the loss of the ability to orient the hand and grasp, manipulate, and carry objects, functions…”
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Direct RNA sequencing reveals m6A modifications on adenovirus RNA are necessary for efficient splicing by Price, Alexander M., Hayer, Katharina E., McIntyre, Alexa B. R., Gokhale, Nandan S., Abebe, Jonathan S., Della Fera, Ashley N., Mason, Christopher E., Horner, Stacy M., Wilson, Angus C., Depledge, Daniel P., Weitzman, Matthew D.

“…Adenovirus is a nuclear replicating DNA virus reliant on host RNA processing machinery. Processing and metabolism of cellular RNAs can be regulated by METTL3,…”
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Regulation of Synaptic Transmission and Plasticity by Protein Phosphatase 1 by Foley, Karl, McKee, Cody, Nairn, Angus C, Xia, Houhui

“…Protein phosphatases, by counteracting protein kinases, regulate the reversible phosphorylation of many substrates involved in synaptic plasticity, a cellular…”
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The global burden of sepsis: barriers and potential solutions by Rudd, Kristina E, Kissoon, Niranjan, Limmathurotsakul, Direk, Bory, Sotharith, Mutahunga, Birungi, Seymour, Christopher W, Angus, Derek C, West, T Eoin

“…Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases and deaths are estimated to occur in low and middle-income…”
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Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection by Huang, David T, Yealy, Donald M, Filbin, Michael R, Brown, Aaron M, Chang, Chung-Chou H, Doi, Yohei, Donnino, Michael W, Fine, Jonathan, Fine, Michael J, Fischer, Michelle A, Holst, John M, Hou, Peter C, Kellum, John A, Khan, Feras, Kurz, Michael C, Lotfipour, Shahram, LoVecchio, Frank, Peck-Palmer, Octavia M, Pike, Francis, Prunty, Heather, Sherwin, Robert L, Southerland, Lauren, Terndrup, Thomas, Weissfeld, Lisa A, Yabes, Jonathan, Angus, Derek C

“…Differentiating acute bacterial infection from other causes of lower respiratory tract illness is challenging. In this trial, procalcitonin was investigated as…”
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Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis by Seymour, Christopher W, Kennedy, Jason N, Wang, Shu, Chang, Chung-Chou H, Elliott, Corrine F, Xu, Zhongying, Berry, Scott, Clermont, Gilles, Cooper, Gregory, Gomez, Hernando, Huang, David T, Kellum, John A, Mi, Qi, Opal, Steven M, Talisa, Victor, van der Poll, Tom, Visweswaran, Shyam, Vodovotz, Yoram, Weiss, Jeremy C, Yealy, Donald M, Yende, Sachin, Angus, Derek C

“…IMPORTANCE: Sepsis is a heterogeneous syndrome. Identification of distinct clinical phenotypes may allow more precise therapy and improve care. OBJECTIVE: To…”
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