Search Results - "Angulo, Barbara"

Solute transport modelling in karst conduits with slow zones during different hydrologic conditions by Morales, Tomás, Uriarte, Jesus A., Olazar, Martín, Antigüedad, Iñaki, Angulo, Bárbara

“…Eight tracer tests conducted under different flow conditions in two well-developed karst connections in the Santa Eufemia–Ereñozar karst unit (Basque Country,…”
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A commercial real-time PCR kit provides greater sensitivity than direct sequencing to detect KRAS mutations: a morphology-based approach in colorectal carcinoma by Angulo, Bárbara, García-García, Elena, Martínez, Rebeca, Suárez-Gauthier, Ana, Conde, Esther, Hidalgo, Manuel, López-Ríos, Fernando

“…KRAS mutation testing has become a standard procedure in the management of patients with carcinomas. The most frequently used method for KRAS testing is direct…”
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Comparison of testing methods for the detection of BRAF V600E mutations in malignant melanoma: pre-approval validation study of the companion diagnostic test for vemurafenib by Lopez-Rios, Fernando, Angulo, Barbara, Gomez, Belen, Mair, Debbie, Martinez, Rebeca, Conde, Esther, Shieh, Felice, Vaks, Jeffrey, Langland, Rachel, Lawrence, H Jeffrey, de Castro, David Gonzalez

“…The cobas 4800 BRAF V600 Mutation Test is a CE-marked and FDA-approved in vitro diagnostic assay used to select patients with metastatic melanoma for treatment…”
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Implementing a comprehensive approach for evaluating significance and disturbance in protected karst areas to guide management strategies by Angulo, Bárbara, Morales, Tomás, Uriarte, Jesús A., Antigüedad, Iñaki

“…Many environmental studies have acquired an almost exclusively biotic perspective over the years, neglecting important key land characteristics like those of a…”
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Molecular Context of the EGFR Mutations: Evidence for the Activation of mTOR/S6K Signaling by Conde, Esther, Angulo, Barbara, Tang, Moying, Morente, Manuel, Torres-Lanzas, Juan, Lopez-Encuentra, Angel, Lopez-Rios, Fernando, Sanchez-Cespedes, Montserrat

“…Purpose: Activating somatic mutations in the epidermal growth factor receptor ( EGFR ) gene are present in a small subset of lung adenocarcinomas. These…”
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Hydraulic conductivity characterization of a karst recharge area using water injection tests and electrical resistivity logging by Angulo, Bárbara, Morales, Tomás, Uriarte, Jesús A., Antigüedad, Iñaki

“…Water injection tests and electrical logging are particularly useful techniques in the characterization of geological media in engineering works. In this paper…”
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A comparison of EGFR mutation testing methods in lung carcinoma: direct sequencing, real-time PCR and immunohistochemistry by Angulo, Bárbara, Conde, Esther, Suárez-Gauthier, Ana, Plaza, Carlos, Martínez, Rebeca, Redondo, Pilar, Izquierdo, Elisa, Rubio-Viqueira, Belén, Paz-Ares, Luis, Hidalgo, Manuel, López-Ríos, Fernando

“…The objective of this study is to compare two EGFR testing methodologies (a commercial real-time PCR kit and a specific EGFR mutant immunohistochemistry), with…”
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Characterization of flow and transport dynamics in karst aquifers by analyzing tracer test results in conduits and recharge areas (the Egino Massif, Basque Country, Spain): environmental and management implications by Morales, Tomás, Uriarte, Jesus A., Angulo, Bárbara, Olazar, Martín, Arandes, Jose M., Antigüedad, Iñaki

“…Karst aquifers contribute to supplying drinking water to almost a quarter of the world´s population. Their complex dynamics requires specific approaches aimed…”
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The use of P63 immunohistochemistry for the identification of squamous cell carcinoma of the lung by Conde, Esther, Angulo, Bárbara, Redondo, Pilar, Toldos, Oscar, García-García, Elena, Suárez-Gauthier, Ana, Rubio-Viqueira, Belén, Marrón, Carmen, García-Luján, Ricardo, Sánchez-Céspedes, Montse, López-Encuentra, Angel, Paz-Ares, Luis, López-Ríos, Fernando

“…While some targeted agents should not be used in squamous cell carcinomas (SCCs), other agents might preferably target SCCs. In a previous microarray study,…”
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A new generation of companion diagnostics: cobas BRAF, KRAS and EGFR mutation detection tests by Angulo, Barbara, Lopez-Rios, Fernando, Gonzalez, David

“…The cobas(®) (Roche) portfolio of companion diagnostics in oncology currently has three assays CE-marked for in vitro diagnostics. Two of these (EGFR and BRAF)…”
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Hybridization for human epidermal growth factor receptor 2 testing in gastric carcinoma: a comparison of fluorescence in-situ hybridization with a novel fully automated dual-colour silver in-situ hybridization method by García-García, Elena, Gómez-Martín, Carlos, Angulo, Bárbara, Conde, Esther, Suárez-Gauthier, Ana, Adrados, Magdalena, Perna, Cristian, Rodríguez-Peralto, José Luis, Hidalgo, Manuel, López-Ríos, Fernando

“…García‐García E, Gómez‐Martín C, Angulo B, Conde E, Suárez‐Gauthier A, Adrados M, Perna C, Rodríguez‐Peralto J L, Hidalgo M & López‐Ríos F 
(2011)…”
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Genomic Profiling of HER2‐Positive Gastric Cancer: PI3K/Akt/mTOR Pathway as Predictor of Outcomes in HER2‐Positive Advanced Gastric Cancer Treated with Trastuzumab by Díaz‐Serrano, Asunción, Angulo, Barbara, Dominguez, Carolina, Pazo‐Cid, Roberto, Salud, Antonieta, Jiménez‐Fonseca, Paula, Leon, Ana, Galan, Maria Carmen, Alsina, Maria, Rivera, Fernando, Plaza, J. Carlos, Paz‐Ares, Luis, Lopez‐Rios, Fernando, Gómez‐Martín, Carlos

“…Background HER2‐positive gastric cancer (GC) affects 7%–34% of patients with GC. Trastuzumab‐based first‐line treatment has become the standard of care for…”
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The ALK translocation in advanced non-small-cell lung carcinomas: preapproval testing experience at a single cancer centre by Conde, Esther, Angulo, Bárbara, Izquierdo, Elisa, Muñoz, Luna, Suárez-Gauthier, Ana, Plaza, Carlos, Dominguez, Nuria, Torres, Maribel, Madrigal, Luis, Rubio-Viqueira, Belén, Belda-Iniesta, Cristobal, Hidalgo, Manuel, López-Ríos, Fernando

“…Aims To study the ALK translocation in patients with advanced non‐small‐cell lung carcinomas (NSCLCs) seen at a European cancer centre, and its association…”
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gene-alteration profile of human lung cancer cell lines by Blanco, Raquel, Iwakawa, Reika, Tang, Moying, Kohno, Takashi, Angulo, Barbara, Pio, Ruben, Montuenga, Luis M, Minna, John D, Yokota, Jun, Sanchez-Cespedes, Montse

“…Aberrant proteins encoded from genes altered in tumors drive cancer development and may also be therapeutic targets. Here we derived a comprehensive…”
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Comparison of molecular testing methods for the detection of EGFR mutations in formalin-fixed paraffin-embedded tissue specimens of non-small cell lung cancer by Lopez-Rios, Fernando, Angulo, Barbara, Gomez, Belen, Mair, Debbie, Martinez, Rebeca, Conde, Esther, Shieh, Felice, Tsai, Julie, Vaks, Jeffrey, Current, Robert, Lawrence, H Jeffrey, Gonzalez de Castro, David

“…To conduct a methods correlation study of three different assays for the detection of mutations at EGFR gene in human formalin-fixed paraffin-embedded tumour…”
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Aligning digital CD8+ scoring and targeted next‐generation sequencing with programmed death ligand 1 expression: a pragmatic approach in early‐stage squamous cell lung carcinoma by Conde, Esther, Caminoa, Alejandra, Dominguez, Carolina, Calles, Antonio, Walter, Stefan, Angulo, Barbara, Sánchez, Elena, Alonso, Marta, Jimenez, Luis, Madrigal, Luis, Hernando, Florentino, Sanz‐Ortega, Julian, Jimenez, Beatriz, Garrido, Pilar, Paz‐Ares, Luis, Castro, Javier, Hernandez, Susana, Lopez‐Rios, Fernando

“…Aims To study programmed death ligand 1 (PD‐L1) expression, tumour‐infiltrating T lymphocytes (TILs) and the molecular context in patients with early‐stage…”
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PI3K upregulation as a negative predictive factor of survival in HER2 amplified gastric cancer treated with Trastuzumab by Díaz-Serrano, Asunción, Lopez-Rios, Fernando, Dominguez, Carolina, Fonseca, Paula J., Angulo, Barbara, Pazo Cid, Roberto A., Plaza, Carlos, Rivera, Fernando, Rodriguez, Margarita, Leon, Ana, Hernandez Prieto, Susana, Paz-Ares, Luis, Gomez-Martin, Carlos

“…Abstract only…”
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Gene amplification of the transcription factor DP1 and CTNND1 in human lung cancer by Castillo, Sandra D., Angulo, Barbara, Suarez-Gauthier, Ana, Melchor, Lorenzo, Medina, Pedro P., Sanchez-Verde, Lydia, Torres-Lanzas, Juan, Pita, Guillermo, Benitez, Javier, Sanchez-Cespedes, Montse

“…The search for novel oncogenes is important because they could be the target of future specific anticancer therapies. In the present paper we report the…”
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Detection of actionable oncogene drivers alterations in HER2 -amplified gastric cancer by next generation sequencing by Gomez-Martin, Carlos, Pazo Cid, Roberto A., Salud, Antonieta, Fonseca, Paula J., Leon, Ana, Galan, MaCarmen, Visa, Laura, Rivera, Fernando, Alsina, Maria, Plaza, Carlos, Angulo, Barbara, Hernandez Prieto, Susana, Dominguez, Carolina, Rodriguez Garcia, Margarita, Del Valle, Elena, Fernandez, Soledad, Rojo, Federico, Cuatrecasas, Miriam, Lopez-Rios, Fernando

“…Abstract only 67 Background: HER2 amplified cases are the only subset of gastric carcinoma (GC) patients with an approved targeted therapy (≈20%). In GC it is…”
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Transcriptional targets of the chromatin-remodelling factor SMARCA4/BRG1 in lung cancer cells by Medina, Pedro P., Carretero, Julian, Ballestar, Esteban, Angulo, Barbara, Lopez-Rios, Fernando, Esteller, Manel, Sanchez-Cespedes, Montserrat

“…BRG1, also called SMARCA4, is the catalytic subunit of the SWI/SNF chromatin-remodelling complex and influences transcriptional regulation by disrupting…”
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