Search Results - "Angotti, Marc"
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The adrenocortical tumor cell line NCI-H295R as an in vitro screening system for the evaluation of CYP11B2 (aldosterone synthase) and CYP11B1 (steroid-11β-hydroxylase) inhibitors
Published in The Journal of steroid biochemistry and molecular biology (01-08-2005)“…Aldosterone plays a key role in salt and water homeostasis but is also involved in the development and progression of congestive heart failure and myocardial…”
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Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3, 4-dihydronaphthalen-1(2H)-one on all-trans and 13-cis-retinoic acid levels in plasma quantified by high perfomance liquid chromatography coupled to tandem mass spectrometry
Published in Journal of enzyme inhibition and medicinal chemistry (01-06-2005)“…The effect of the titled tetralone as a retinoic acid metabolism blocking agent (RAMBA) in vivo in comparison with ketoconazole, a well known cytochrome P450…”
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Characterization by matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry of the major photoproducts of temoporfin (m-THPC) and bacteriochlorin (m-THPBC)
Published in Journal of mass spectrometry. (01-07-2001)“…The photobleaching of 5,10,15,20‐tetrakis(m‐hydroxyphenyl)chlorin (temoporfin, m‐THPC) and 5,10,15,20‐tetrakis(m‐hydroxyphenyl)bacteriochlorin…”
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Matrix-assisted laser desorption/Ionization coupled to Fourier transform ion cyclotron resonance mass spectrometry: a method to characterize temoporpfin photoproducts
Published in Rapid communications in mass spectrometry (15-04-1999)“…Temoporpfin (m‐THPC) has been developed as a new photodynamic therapeutic agent and is currently under clinical trials for the treatment of malignant tumors…”
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