Search Results - "Angleton, Eddie L"

Novel Lipoglycopeptides as Inhibitors of Bacterial Signal Peptidase I by Kulanthaivel, Palaniappan, Kreuzman, Adam J, Strege, Mark A, Belvo, Matthew D, Smitka, Tim A, Clemens, Matthew, Swartling, James R, Minton, Kristina L, Zheng, Feng, Angleton, Eddie L, Mullen, Deborah, Jungheim, Louis N, Klimkowski, Valentine J, Nicas, Thalia I, Thompson, Richard C, Peng, Sheng-Bin

“…Signal peptidase (SPase) I is responsible for the cleavage of signal peptides of many secreted proteins in bacteria. Because of its unique physiological and…”
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Structure of an inhibitor complex of the proteinase from feline immunodeficiency virus by Wlodawer, Alexander, Gustchina, Alla, Reshetnikova, Ludmila, Lubkowski, Jacek, Zdanov, Alexander, Hui, Kwan Y, Angleton, Eddie L, Farmerie, William G, Goodenow, Maureen M, Bhatt, Deepa, Zhang, Li, Dunn, Ben M

“…The crystal structure of a recombinant form of the proteinase encoded by the feline immunodeficiency virus (FIV PR) has been solved at 2 A resolution and…”
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Development of an Internally Quenched Fluorescent Substrate and a Continuous Fluorimetric Assay for Streptococcus pneumoniae Signal Peptidase I by Peng, Sheng-Bin, Zheng, Feng, Angleton, Eddie L, Smiley, David, Carpenter, John, Scott, John E

“…Signal peptidase (SPase) I is responsible for the cleavage of signal peptides of many secreted proteins in bacteria and serves as a potential target for the…”
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In vitro and in vivo self‐cleavage of Streptococcus pneumoniae signal peptidase I by Zheng, Feng, Angleton, Eddie L., Lu, Jin, Peng, Sheng‐Bin

“…We have previously demonstrated that Streptococcus pneumoniae signal peptidase (SPase) I catalyzes a self‐cleavage to result in a truncated product,…”
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Preparation and reconstitution with divalent metal ions of class I and class II Clostridium histolyticum apocollagenases by Angleton, Eddie L, Van Wart, Harold E

“…Both gamma- and zeta-collagenases from Clostridium histolyticum are fully and reversibly inhibited by 1,10-phenanthroline at pH 7.5 in the presence of 10 mM…”
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Preparation by direct metal exchange and kinetic study of active site metal substituted class I and class II Clostridium histolyticum collagenases by Angleton, Eddie L, Van Wart, Harold E

“…Active site metal substitutions for both gamma- and zeta-collagenases from Clostridium histolyticum have been made by direct metal exchange. The incubation of…”
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Minimal sequence requirement of thrombin receptor agonist peptide by Hui, K Y, Jakubowski, J A, Wyss, V L, Angleton, E L

“…A site-specific proteolytically generated neoamino terminus of the thrombin receptor having a sequence SFLLRNPNDKYEPF- has been reported to be a functional…”
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Model peptides to study the effects of P 2 and P 3 substitutions in statine-containing HIV proteinase inhibitors by Hui, Kwan Y., Hermann, Robert B., Manetta, Joseph V., Gygi, Theresa, Angleton, Eddie L.

“…Through a series of synthetic model peptides, we have examined the structural requirements of the P 2 and P 3 residues in statine-based HIV protease (PR)…”
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Model peptides to study the effects of P2 and P3 substitutions in statine‐containing HIV proteinase inhibitors by Hui, Kwan Y., Hermann, Robert B., Manetta, Joseph V., Gygi, Theresa, Angleton, Eddie L.

“…Through a series of synthetic model peptides, we have examined the structural requirements of the P2 and P3 residues in statine‐based HIV protease (PR)…”
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Multiple Modes of Activation of Latent Human Fibroblast Collagenase: Evidence for the Role of a Cys73Active-Site Zinc Complex in Latency and a "Cysteine Switch" Mechanism for Activation by Springman, Eric B., Angleton, Eddie L., Birkedal-Hansen, Henning, Van Wart, Harold E.

“…Latent human fibroblast collagenase (HFC) can be activated by a variety of seemingly disparate means. In addition to the well-characterized activation by…”
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