Search Results - "Angius, Andrea"

DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy by Greco, Carolina M., Kunderfranco, Paolo, Rubino, Marcello, Larcher, Veronica, Carullo, Pierluigi, Anselmo, Achille, Kurz, Kerstin, Carell, Thomas, Angius, Andrea, Latronico, Michael V. G., Papait, Roberto, Condorelli, Gianluigi

“…Methylation at 5-cytosine (5-mC) is a fundamental epigenetic DNA modification associated recently with cardiac disease. In contrast, the role of…”
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A Novel Affordable and Reliable Framework for Accurate Detection and Comprehensive Analysis of Somatic Mutations in Cancer by Atzeni, Rossano, Massidda, Matteo, Pieroni, Enrico, Rallo, Vincenzo, Pisu, Massimo, Angius, Andrea

“…Accurate detection and analysis of somatic variants in cancer involve multiple third-party tools with complex dependencies and configurations, leading to…”
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Genetic Variants Regulating Immune Cell Levels in Health and Disease by Orrù, Valeria, Steri, Maristella, Sole, Gabriella, Sidore, Carlo, Virdis, Francesca, Dei, Mariano, Lai, Sandra, Zoledziewska, Magdalena, Busonero, Fabio, Mulas, Antonella, Floris, Matteo, Mentzen, Wieslawa I., Urru, Silvana A.M., Olla, Stefania, Marongiu, Michele, Piras, Maria G., Lobina, Monia, Maschio, Andrea, Pitzalis, Maristella, Urru, Maria F., Marcelli, Marco, Cusano, Roberto, Deidda, Francesca, Serra, Valentina, Oppo, Manuela, Pilu, Rosella, Reinier, Frederic, Berutti, Riccardo, Pireddu, Luca, Zara, Ilenia, Porcu, Eleonora, Kwong, Alan, Brennan, Christine, Tarrier, Brendan, Lyons, Robert, Kang, Hyun M., Uzzau, Sergio, Atzeni, Rossano, Valentini, Maria, Firinu, Davide, Leoni, Lidia, Rotta, Gianluca, Naitza, Silvia, Angius, Andrea, Congia, Mauro, Whalen, Michael B., Jones, Chris M., Schlessinger, David, Abecasis, Gonçalo R., Fiorillo, Edoardo, Sanna, Serena, Cucca, Francesco

“…The complex network of specialized cells and molecules in the immune system has evolved to defend against pathogens, but inadvertent immune system attacks on…”
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Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools by Ding, Jun, Sidore, Carlo, Butler, Thomas J, Wing, Mary Kate, Qian, Yong, Meirelles, Osorio, Busonero, Fabio, Tsoi, Lam C, Maschio, Andrea, Angius, Andrea, Kang, Hyun Min, Nagaraja, Ramaiah, Cucca, Francesco, Abecasis, Gonçalo R, Schlessinger, David

“…DNA sequencing identifies common and rare genetic variants for association studies, but studies typically focus on variants in nuclear DNA and ignore the…”
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Loss of Mismatched HLA in Leukemia after Stem-Cell Transplantation by Vago, Luca, Perna, Serena Kimi, Zanussi, Monica, Mazzi, Benedetta, Barlassina, Cristina, Stanghellini, Maria Teresa Lupo, Perrelli, Nicola Flavio, Cosentino, Cristian, Torri, Federica, Angius, Andrea, Forno, Barbara, Casucci, Monica, Bernardi, Massimo, Peccatori, Jacopo, Corti, Consuelo, Bondanza, Attilio, Ferrari, Maurizio, Rossini, Silvano, Roncarolo, Maria Grazia, Bordignon, Claudio, Bonini, Chiara, Ciceri, Fabio, Fleischhauer, Katharina

“…Five patients with acute myelogenous leukemia received hematopoietic stem-cell transplants from a haploidentical donor. They also received T cells from the…”
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The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging by Egorov, Evgeny S, Kasatskaya, Sofya A, Zubov, Vasiliy N, Izraelson, Mark, Nakonechnaya, Tatiana O, Staroverov, Dmitriy B, Angius, Andrea, Cucca, Francesco, Mamedov, Ilgar Z, Rosati, Elisa, Franke, Andre, Shugay, Mikhail, Pogorelyy, Mikhail V, Chudakov, Dmitriy M, Britanova, Olga V

“…Human aging is associated with a profound loss of thymus productivity, yet naïve T lymphocytes still maintain their numbers by division in the periphery for…”
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Quantitative Metabolomics to Explore the Role of Plasma Polyamines in Colorectal Cancer by Coradduzza, Donatella, Arru, Caterina, Culeddu, Nicola, Congiargiu, Antonella, Azara, Emanuela Gigliola, Scanu, Antonio Mario, Zinellu, Angelo, Muroni, Maria Rosaria, Rallo, Vincenzo, Medici, Serenella, Carru, Ciriaco, Angius, Andrea, De Miglio, Maria Rosaria

“…Colorectal cancer (CRC) is one of the major public health and socio-economic problems, which management demands the development of non-invasive screening…”
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Biomarker dynamics affecting neoadjuvant therapy response and outcome of HER2-positive breast cancer subtype by Orrù, Sandra, Pascariello, Emanuele, Pes, Barbara, Rallo, Vincenzo, Barbara, Raffaele, Muntoni, Marta, Notari, Francesca, Fancello, Gianfranco, Mocci, Cristina, Muroni, Maria Rosaria, Cossu-Rocca, Paolo, Angius, Andrea, De Miglio, Maria Rosaria

“…HER2+ breast cancer (BC) is an aggressive subtype genetically and biologically heterogeneous. We evaluate the predictive and prognostic role of HER2…”
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Portrait of Cancer Stem Cells on Colorectal Cancer: Molecular Biomarkers, Signaling Pathways and miRNAome by Angius, Andrea, Scanu, Antonio Mario, Arru, Caterina, Muroni, Maria Rosaria, Rallo, Vincenzo, Deiana, Giulia, Ninniri, Maria Chiara, Carru, Ciriaco, Porcu, Alberto, Pira, Giovanna, Uva, Paolo, Cossu-Rocca, Paolo, De Miglio, Maria Rosaria

“…Colorectal cancer (CRC) is a leading cause of cancer death worldwide, and about 20% is metastatic at diagnosis and untreatable. Increasing evidence suggests…”
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A novel null homozygous mutation confirms CACNA2D2 as a gene mutated in epileptic encephalopathy by Pippucci, Tommaso, Parmeggiani, Antonia, Palombo, Flavia, Maresca, Alessandra, Angius, Andrea, Crisponi, Laura, Cucca, Francesco, Liguori, Rocco, Valentino, Maria Lucia, Seri, Marco, Carelli, Valerio

“…Contribution to epileptic encephalopathy (EE) of mutations in CACNA2D2, encoding α2δ-2 subunit of Voltage Dependent Calcium Channels, is unclear. To date only…”
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Assessing the Predictive Power of the Hemoglobin/Red Cell Distribution Width Ratio in Cancer: A Systematic Review and Future Directions by Coradduzza, Donatella, Medici, Serenella, Chessa, Carla, Zinellu, Angelo, Madonia, Massimo, Angius, Andrea, Carru, Ciriaco, De Miglio, Maria Rosaria

“…: The hemoglobin (Hb)/red cell distribution width (RDW) ratio has emerged as an accessible, repeatable, and inexpensive prognostic factor that may predict…”
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Prognostic Impact of Membranous/Nuclear Epidermal Growth Factor Receptor Localization in Clear Cell Renal Cell Carcinoma by Muroni, Maria Rosaria, Ribback, Silvia, Sotgiu, Giovanni, Kroeger, Nils, Saderi, Laura, Angius, Andrea, Cossu-Rocca, Paolo, De Miglio, Maria Rosaria

“…EGFR is overexpressed in the majority of clear cell renal cell carcinomas (CCRCCs). Although EGFR deregulation was found to be of great significance in CCRCC…”
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Transcriptome organization of white blood cells through gene co-expression network analysis in a large RNA-seq dataset by Forabosco, Paola, Pala, Mauro, Crobu, Francesca, Diana, Maria Antonietta, Marongiu, Mara, Cusano, Roberto, Angius, Andrea, Steri, Maristella, Orrù, Valeria, Schlessinger, David, Fiorillo, Edoardo, Devoto, Marcella, Cucca, Francesco

“…Gene co-expression network analysis enables identification of biologically meaningful clusters of co-regulated genes (modules) in an unsupervised manner. We…”
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Integrated Analysis of miRNA and mRNA Endorses a Twenty miRNAs Signature for Colorectal Carcinoma by Angius, Andrea, Uva, Paolo, Pira, Giovanna, Muroni, Maria Rosaria, Sotgiu, Giovanni, Saderi, Laura, Uleri, Elena, Caocci, Maurizio, Ibba, Gabriele, Cesaraccio, Maria Rosaria, Serra, Caterina, Carru, Ciriaco, Manca, Alessandra, Sanges, Francesca, Porcu, Alberto, Dolei, Antonia, Scanu, Antonio Mario, Rocca, Paolo Cossu, De Miglio, Maria Rosaria

“…Colorectal cancer (CRC) ranks as the most frequent carcinoma worldwide. CRC patients show strong prognostic differences and responses to treatment, and 20%…”
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Gut Microbiota Functional Dysbiosis Relates to Individual Diet in Subclinical Carotid Atherosclerosis by Baragetti, Andrea, Severgnini, Marco, Olmastroni, Elena, Dioguardi, Carola Conca, Mattavelli, Elisa, Angius, Andrea, Rotta, Luca, Cibella, Javier, Caredda, Giada, Consolandi, Clarissa, Grigore, Liliana, Pellegatta, Fabio, Giavarini, Flavio, Caruso, Donatella, Norata, Giuseppe Danilo, Catapano, Alberico Luigi, Peano, Clelia

“…Gut Microbiota (GM) dysbiosis associates with Atherosclerotic Cardiovascular Diseases (ACVD), but whether this also holds true in subjects without clinically…”
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Landscape of transcriptome variations uncovering known and novel driver events in colorectal carcinoma by Pira, Giovanna, Uva, Paolo, Scanu, Antonio Mario, Rocca, Paolo Cossu, Murgia, Luciano, Uleri, Elena, Piu, Claudia, Porcu, Alberto, Carru, Ciriaco, Manca, Alessandra, Persico, Ivana, Muroni, Maria Rosaria, Sanges, Francesca, Serra, Caterina, Dolei, Antonia, Angius, Andrea, De Miglio, Maria Rosaria

“…We focused on an integrated view of genomic changes in Colorectal cancer (CRC) and distant normal colon tissue (NTC) to test the effectiveness of expression…”
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A large-scale screening identified in USH2A gene the P3272L founder pathogenic variant explaining familial Usher syndrome in Sardinia, Italy by Serra, Rita, Rallo, Vincenzo, Steri, Maristella, Olla, Stefania, Piras, Maria Grazia, Marongiu, Michele, Gorospe, Myriam, Schlessinger, David, Pinna, Antonio, Fiorillo, Edoardo, Cucca, Francesco, Angius, Andrea

“…Usher syndrome (USH) encompasses a group of disorders characterized by congenital sensorineural hearing loss (SNHL) and retinitis pigmentosa (RP). We described…”
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Epigenetics, Stem Cells, and Autophagy: Exploring a Path Involving miRNA by Balzano, Francesca, Campesi, Ilaria, Cruciani, Sara, Garroni, Giuseppe, Bellu, Emanuela, Dei Giudici, Silvia, Angius, Andrea, Oggiano, Annalisa, Rallo, Vincenzo, Capobianco, Giampiero, Dessole, Salvatore, Ventura, Carlo, Montella, Andrea, Maioli, Margherita

“…MiRNAs, a small family of non-coding RNA, are now emerging as regulators of stem cell pluripotency, differentiation, and autophagy, thus controlling stem cell…”
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Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe by Sikora, Martin, Carpenter, Meredith L, Moreno-Estrada, Andres, Henn, Brenna M, Underhill, Peter A, Sánchez-Quinto, Federico, Zara, Ilenia, Pitzalis, Maristella, Sidore, Carlo, Busonero, Fabio, Maschio, Andrea, Angius, Andrea, Jones, Chris, Mendoza-Revilla, Javier, Nekhrizov, Georgi, Dimitrova, Diana, Theodossiev, Nikola, Harkins, Timothy T, Keller, Andreas, Maixner, Frank, Zink, Albert, Abecasis, Goncalo, Sanna, Serena, Cucca, Francesco, Bustamante, Carlos D

“…Genome sequencing of the 5,300-year-old mummy of the Tyrolean Iceman, found in 1991 on a glacier near the border of Italy and Austria, has yielded new insights…”
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Harnessing Minimal Residual Disease as a Predictor for Colorectal Cancer: Promising Horizons Amidst Challenges by Wen, Xiaofen, Coradduzza, Donatella, Shen, Jiaxin, Scanu, Antonio Mario, Muroni, Maria Rosaria, Massidda, Matteo, Rallo, Vincenzo, Carru, Ciriaco, Angius, Andrea, De Miglio, Maria Rosaria

“…Minimal Residual Disease (MRD) detection has emerged as an independent factor in clinical and pathological cancer assessment offering a highly effective method…”
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