Aspartame-Stabilized Gold–Silver Bimetallic Biocompatible Nanostructures with Plasmonic Photothermal Properties, Antibacterial Activity, and Long-Term Stability

Gold–silver core–shell nanoparticles stabilized with a common sweetener, aspartame (AuNP@Ag@Asm), combine the antimicrobial properties of silver with the photoinduced plasmon-mediated photothermal effects of gold. The particles were tested with several bacterial strains, while biocompatibility was v...

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Bibliographic Details
Published in:	Journal of the American Chemical Society Vol. 136; no. 50; pp. 17394 - 17397
Main Authors:	Fasciani, Chiara, Silvero, M. Jazmin, Anghel, Maria Alexandra, Argüello, Gerardo A, Becerra, Maria Cecilia, Scaiano, Juan C
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 17-12-2014
Subjects:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Aspartame - chemistry Aspartame - pharmacology Drug Stability Fibroblasts - drug effects Gold - chemistry Humans Metal Nanoparticles - chemistry Microbial Sensitivity Tests Microscopy, Electron, Transmission Molecular Structure Silver - chemistry Staphylococcus aureus - drug effects Time Factors
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Summary:	Gold–silver core–shell nanoparticles stabilized with a common sweetener, aspartame (AuNP@Ag@Asm), combine the antimicrobial properties of silver with the photoinduced plasmon-mediated photothermal effects of gold. The particles were tested with several bacterial strains, while biocompatibility was verified with human dermal fibroblasts.
ISSN:	0002-7863 1520-5126
DOI:	10.1021/ja510435u