Safety and Efficacy of Percutaneous Morton Neuroma Cryoneurolysis Under Ultrasound Guidance

Purpose To assess the technical success, safety and early efficacy of Morton neuroma (MN) cryoneurolysis. Materials and Methods Retrospective review of 54 consecutive patients with MN treated with cryoneurolysis after failure of conservative treatment, from September 2022 to June 2023. Outcomes meas...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology Vol. 47; no. 6; pp. 795 - 800
Main Authors: Moulin, Benjamin, Angelopoulos, Giorgio, Sarrazin, Jean Luc, Romano, Stephane, Vignaux, Olivier, Guenoun, Thierry, Di Primio, Massimiliano, Hakime, Antoine
Format: Journal Article
Language:English
Published: New York Springer US 01-06-2024
Springer Nature B.V
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Summary:Purpose To assess the technical success, safety and early efficacy of Morton neuroma (MN) cryoneurolysis. Materials and Methods Retrospective review of 54 consecutive patients with MN treated with cryoneurolysis after failure of conservative treatment, from September 2022 to June 2023. Outcomes measurements included technical success (defined a successful ultrasound-guided placement of the cryoprobe), procedural safety according to Cirse classification and change in 6 months post-procedure by pain numeric rating scale (pNRS). Results A total of 59 MN were treated during 55 procedures. Mean procedure duration was 47 min, all patients were discharged 2 h after the intervention. Technical success was 98.1%. No Cirse grade 3, 4 or 5 complication was reported. Three grade 2 complication occurred, including two chilblain-type lesions and one bone insufficiency fracture. At 6 months post-procedure, pNRS score was significantly decreased (2.7 ± 2.2 vs 7.1 ± 1.1) ( p  < 0.0001), with a mean score decrease of 4.1points. Thirty-two patients (60.4%) reported a complete pain relief, 15 (28.3%) a partial pain relief and 6 (11.3%) no pain relief, or increased pain. Conclusion Cryoneurolysis seems to be safe for the treatment of Morton neuroma. Six-month pain relief is promising and needs to be confirmed at long term. Graphical Abstract
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ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-024-03669-1