Clinical effect of a mouth rinse containing Ocimum gratissimum on plaque and gingivitis control

The effect of Ocimum gratissimum (Og) on the reduction of dental plaque and gingivitis was evaluated in a randomized, parallel and double-blind clinical trial. Subjects were randomly allocated to the control group (n=10)-mouth rinse with no antiseptic agents; CLX group (n=10)-mouth rinse containing...

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Bibliographic Details
Published in:	The journal of contemporary dental practice Vol. 12; no. 5; pp. 350 - 355
Main Authors:	Pereira, Sérgio Luís da Silva, de Oliveira, José Weslley Gonçalves, Angelo, Keyles Karla Sá Vieira, da Costa, Angela Maria Alves, Costa, Flávio
Format:	Journal Article
Language:	English
Published:	India 01-09-2011
Subjects:	Adult Anti-Infective Agents, Local - therapeutic use Chlorhexidine - analogs & derivatives Chlorhexidine - therapeutic use Dental Plaque - classification Dental Plaque - prevention & control Dental Plaque Index Dentistry Double-Blind Method Female Follow-Up Studies Gingivitis - classification Gingivitis - prevention & control Humans Male Mouthwashes - therapeutic use Ocimum Periodontal Index Phytotherapy Plant Preparations - therapeutic use
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Summary:	The effect of Ocimum gratissimum (Og) on the reduction of dental plaque and gingivitis was evaluated in a randomized, parallel and double-blind clinical trial. Subjects were randomly allocated to the control group (n=10)-mouth rinse with no antiseptic agents; CLX group (n=10)-mouth rinse containing chlorhexidine digluconate or Og group (n=10)-mouth rinse containing Ocimum gratissimum. Plaque (PLI) and bleeding (BI) indexes were assessed at days 0 and after 3 months. Subjects were asked to brush their teeth with a fluoridated dentifrice, three times a day, during a 90-day period. After each brushing they rinsed with one of the three mouth rinses during 1 minute. There was a significant reduction on plaque and gingivitis in tests groups (p < 0.05), but no statistically significant difference was observed among them (p > 0.05). Mouth rinse containing Og was effective as antiplaque and antigingivitis agent, in a similar manner that chlorhexidine digluconate. Research in treatment of chronic oral diseases using natural agents must be encouraged to verify which would be a useful addition to the current range of chemotherapeutic treatment options.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-News-1 ObjectType-Feature-3 content type line 23
ISSN:	1526-3711 1526-3711
DOI:	10.5005/jp-journals-10024-1058