Search Results - "Angelis, De"
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Epigenetic germline inheritance of diet-induced obesity and insulin resistance
Published in Nature genetics (01-05-2016)“…Johannes Beckers, Martin Hrabě de Angelis and colleagues use in vitro fertilization to demonstrate epigenetic germline inheritance of acquired metabolic…”
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Fibroblast Growth Factor 21—Metabolic Role in Mice and Men
Published in Endocrine reviews (01-10-2017)“…Since its identification in 2000, the interest of scientists in the hepatokine fibroblast growth factor (FGF) 21 has tremendously grown, and still remains…”
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3
Host microbiota constantly control maturation and function of microglia in the CNS
Published in Nature neuroscience (01-07-2015)“…In this study, the authors show that host microbiota play a key role in modulating microglia homeostasis. Germ-free mice or mice with only limited microbiota…”
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Treatment landscape of triple-negative breast cancer — expanded options, evolving needs
Published in Nature reviews. Clinical oncology (01-02-2022)“…Tumour heterogeneity and a long-standing paucity of effective therapies other than chemotherapy have contributed to triple-negative breast cancer (TNBC) being…”
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Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes
Published in Nature medicine (01-01-2021)“…The state of intermediate hyperglycemia is indicative of elevated risk of developing type 2 diabetes 1 . However, the current definition of prediabetes neither…”
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Blind to carbon risk? An analysis of stock market reaction to the Paris Agreement
Published in Ecological economics (01-04-2020)“…It is increasingly recognized that a transition to sustainable finance is crucial to scale up the low-carbon investments needed to achieve the global climate…”
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7
Standard Model EFTs via on-shell methods
Published in The journal of high energy physics (29-11-2021)“…A bstract We present the Standard Model Effective Field Theories (SMEFT) from purely on-shell arguments. Starting from few basics assumptions such as Poincaré…”
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Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach
Published in Diabetes (New York, N.Y.) (01-02-2013)“…Metabolomic discovery of biomarkers of type 2 diabetes (T2D) risk may reveal etiological pathways and help to identify individuals at risk for disease. We…”
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Modeling Materials and Processes in Hybrid/Organic Photovoltaics: From Dye-Sensitized to Perovskite Solar Cells
Published in Accounts of chemical research (18-11-2014)“…Over the last 2 decades, researchers have invested enormous research effort into hybrid/organic photovoltaics, leading to the recent launch of the first…”
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Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance
Published in The Journal of clinical investigation (01-02-2017)“…Dietary intake of saturated fat is a likely contributor to nonalcoholic fatty liver disease (NAFLD) and insulin resistance, but the mechanisms that initiate…”
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Amplitude bases in generic EFTs
Published in The journal of high energy physics (30-08-2022)“…A bstract We present for the first time an efficient algorithm to find a basis of kinematically independent structures built of (massless and massive) spinor…”
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Giant Nonlinear Response at the Nanoscale Driven by Bound States in the Continuum
Published in Physical review letters (20-07-2018)“…Being motivated by the recent prediction of high-Q modes in subwavelength dielectric resonators inspired by bound states in the continuum (BIC), we study the…”
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Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders
Published in The EMBO journal (17-09-2014)“…Mutations in the cytosine‐5 RNA methyltransferase NSun2 cause microcephaly and other neurological abnormalities in mice and human. How post‐transcriptional…”
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Relativistic GW calculations on CH3NH3PbI3 and CH3NH3SnI3 Perovskites for Solar Cell Applications
Published in Scientific reports (26-03-2014)“…Hybrid AMX 3 perovskites (A = Cs, CH 3 NH 3 ; M = Sn, Pb; X = halide) have revolutionized the scenario of emerging photovoltaic technologies, with very recent…”
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15
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts
Published in Nature communications (21-10-2014)“…The hormone calcitonin (CT) is primarily known for its pharmacologic action as an inhibitor of bone resorption, yet CT-deficient mice display increased bone…”
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Communicating systems in the body: how microbiota and microglia cooperate
Published in Immunology (01-01-2017)“…Summary Microglia are tissue macrophages of the central nervous system (CNS). Their key tasks are immune surveillance as well as responding to infections or…”
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Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum
Published in PLoS genetics (01-11-2008)“…The rapidly evolving field of metabolomics aims at a comprehensive measurement of ideally all endogenous metabolites in a cell or body fluid. It thereby…”
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Optimal design and performance evaluation of systems with Tuned Mass Damper Inerter (TMDI)
Published in Earthquake engineering & structural dynamics (10-07-2017)“…Summary The paper concerns the optimal design and performance evaluation of a Tuned Mass Damper Inerter (TMDI) to reduce dynamic vibrations. The system…”
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Breast Cancer Stem Cells as Drivers of Tumor Chemoresistance, Dormancy and Relapse: New Challenges and Therapeutic Opportunities
Published in Cancers (15-10-2019)“…Breast cancer is the most frequent cancer among women worldwide. Therapeutic strategies to prevent or treat metastatic disease are still inadequate although…”
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Dynamical Origin of the Rashba Effect in Organohalide Lead Perovskites: A Key to Suppressed Carrier Recombination in Perovskite Solar Cells?
Published in The journal of physical chemistry letters (05-05-2016)“…The presence of a Rashba band-splitting mechanism mediated by spin–orbit coupling and breaking of inversion symmetry has been suggested as a possible cause for…”
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