Search Results - "Angeli, Marc"
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Systematic integrative analysis of gene expression identifies HNF4A as the central gene in pathogenesis of non-alcoholic steatohepatitis
Published in PloS one (07-12-2017)“…Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the Western world, and encompasses a spectrum from simple steatosis to…”
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Estrogen Receptor 1 Inhibition of Wnt/β-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis
Published in Frontiers in oncology (22-11-2021)“…Hepatocellular Carcinoma (HCC) is a sexually dimorphic cancer, with female sex being independently protective against HCC incidence and progression. The aim of…”
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Prioritizing therapeutics for lung cancer: an integrative meta-analysis of cancer gene signatures and chemogenomic data
Published in PLoS computational biology (01-03-2015)“…Repurposing FDA-approved drugs with the aid of gene signatures of disease can accelerate the development of new therapeutics. A major challenge to developing…”
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4
The basis of liver regeneration: A systems biology approach
Published in Annals of hepatology (01-05-2019)“…AbstractIntroductionLiver regeneration is a normal response to liver injury. The aim of this study was to determine the molecular basis of liver regeneration,…”
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Acyl‐CoA Thioesterase 1 Contributes to Transition of Steatosis to Metabolic‐Associated Steatohepatitis
Published in International journal of hepatology (New York) (11-07-2024)“…Background . Metabolic dysfunction‐associated steatohepatitis (MASH) has become the leading cause of chronic liver disease, but there has been no approved…”
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Diabetogenic Effects of Immunosuppression: An Integrative Analysis
Published in Transplantation (01-01-2020)“…BACKGROUND.Posttransplant diabetes mellitus (PTDM) affects up to 50% of solid organ transplant recipients and compromises long-term outcomes. The goal of this…”
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Robust quantitative scratch assay
Published in Bioinformatics (01-05-2016)“…The wound healing assay (or scratch assay) is a technique frequently used to quantify the dependence of cell motility-a central process in tissue repair and…”
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Integrative analysis of layers of data in hepatocellular carcinoma reveals pathway dependencies
Published in World journal of hepatology (27-01-2021)“…The broader use of high-throughput technologies has led to improved molecular characterization of hepatocellular carcinoma (HCC). To comprehensively analyze…”
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Characterization and predictive functional profiles on metagenomic 16S rRNA data of liver transplant recipients: A longitudinal study
Published in Clinical transplantation (01-02-2022)“…Long‐term survival after Liver Transplantation (LT) is often compromised by infectious and metabolic complications. We aimed to delineate alterations in…”
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10
Circulating plant miRNAs can regulate human gene expression in vitro
Published in Scientific reports (08-09-2016)“…While Brassica oleracea vegetables have been linked to cancer prevention, the exact mechanism remains unknown. Regulation of gene expression by cross-species…”
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Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan
Published in Clinical proteomics (18-11-2021)“…Abstract Background and aims Liver transplantation (LT) can be offered to patients with Hepatocellular carcinoma (HCC) beyond Milan criteria. However, there…”
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Epigenetic basis of hepatocellular carcinoma: A network-based integrative meta-analysis
Published in World journal of hepatology (27-01-2018)“…To identify the key epigenetically modulated genes and pathways in HCC by performing an integrative meta-analysis of all major, well-annotated and publicly…”
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The Basis of Liver Regeneration: A Systems Biology Approach
Published in Annals of hepatology (18-09-2018)“…Introduction and aim. Liver regeneration is a normal response to liver injury. The aim of this study was to determine the molecular basis of liver…”
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Prioritizing Therapeutics for Lung Cancer: An Integrative Meta-analysis of Cancer Gene Signatures and Chemogenomic Data: e1004068
Published in PLoS computational biology (01-03-2015)“…Repurposing FDA-approved drugs with the aid of gene signatures of disease can accelerate the development of new therapeutics. A major challenge to developing…”
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15
Retraction Note: Circulating plant miRNAs can regulate human gene expression in vitro
Published in Scientific reports (22-05-2017)“…We are retracting this Article as we no longer have confidence in the data to support our central conclusion – the detection of Brassica oleracea microRNAs in…”
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Retraction: Circulating plant miRNAs can regulate human gene expression in vitro
Published in Scientific reports (22-05-2017)“…This corrects the article DOI: 10.1038/srep32773…”
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