Search Results - "Angela Murphy, E."

Dietary patterns and cancer risk by Steck, Susan E., Murphy, E. Angela

“…Over the past decade, the search for dietary factors on which to base cancer prevention guidelines has led to the rapid expansion of the field of dietary…”
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Early-onset colorectal cancer: initial clues and current views by Hofseth, Lorne J., Hebert, James R., Chanda, Anindya, Chen, Hexin, Love, Bryan L., Pena, Maria M., Murphy, E. Angela, Sajish, Mathew, Sheth, Amit, Buckhaults, Phillip J., Berger, Franklin G.

“…Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in patients <50 years old) has increased at an alarming rate. Although…”
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Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity by Mehrpouya-Bahrami, Pegah, Chitrala, Kumaraswamy Naidu, Ganewatta, Mitra S., Tang, Chuanbing, Murphy, E. Angela, Enos, Reilly T., Velazquez, Kandy T., McCellan, Jamie, Nagarkatti, Mitzi, Nagarkatti, Prakash

“…Obesity is characterized by chronic low-grade, systemic inflammation, altered gut microbiota, and gut barrier disruption. Additionally, obesity is associated…”
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Breast cancer cell–derived microRNA-155 suppresses tumor progression via enhancing immune cell recruitment and antitumor function by Wang, Junfeng, Wang, Quanyi, Guan, Yinan, Sun, Yulu, Wang, Xiaozhi, Lively, Kaylie, Wang, Yuzhen, Luo, Ming, Kim, Julian A, Murphy, E. Angela, Yao, Yongzhong, Cai, Guoshuai, Fan, Daping

“…Evidence suggests that increased microRNA-155 (miR-155) expression in immune cells enhances antitumor immune responses. However, given the reported association…”
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Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance by Davis, J Mark, Murphy, E Angela, Carmichael, Martin D, Davis, Ben

“…Quercetin is one of a broad group of natural polyphenolic flavonoid substances that are being investigated for their widespread health benefits. These benefits…”
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Emodin reduces Breast Cancer Lung Metastasis by suppressing Macrophage-induced Breast Cancer Cell Epithelial-mesenchymal transition and Cancer Stem Cell formation by Liu, Qing, Hodge, Johnie, Wang, Junfeng, Wang, Yuzhen, Wang, Lianming, Singh, Udai, Li, Yong, Yao, Yongzhong, Wang, Dawei, Ai, Walden, Nagarkatti, Prakash, Chen, Hexin, Xu, Peisheng, Murphy, E Angela, Fan, Daping

“…Our previous studies demonstrated that the natural compound emodin blocks the tumor-promoting feedforward interactions between cancer cells and macrophages,…”
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Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer by Bader, Jackie E, Enos, Reilly T, Velázquez, Kandy T, Carson, Meredith S, Nagarkatti, Mitzi, Nagarkatti, Prakash S, Chatzistamou, Ioulia, Davis, J Mark, Carson, James A, Robinson, Cory M, Murphy, E Angela

“…We examined the role of macrophages in inflammation associated with colorectal cancer (CRC). Given the emerging evidence on immune-microbiota interactions in…”
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Exercise training increases mitochondrial biogenesis in the brain by STEINER, Jennifer L, MURPHY, E. Angela, MCCLELLAN, Jamie L, CARMICHAEL, Martin D, DAVIS, J. Mark

“…Increased muscle mitochondria are largely responsible for the increased resistance to fatigue and health benefits ascribed to exercise training. However, very…”
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High Fat Diet-Induced CD8+ T Cells in Adipose Tissue Mediate Macrophages to Sustain Low-Grade Chronic Inflammation by Kiran, Sonia, Kumar, Vijay, Murphy, E. Angela, Enos, Reilly T., Singh, Udai P.

“…Obesity in the United States and worldwide reached epidemic proportions within the last 20 years. Obesity is a very powerful health determinant or indicator…”
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Association between the Dietary Inflammatory Index (DII) and urinary enterolignans and C-reactive protein from the National Health and Nutrition Examination Survey-2003–2008 by Shivappa, Nitin, Wirth, Michael D., Murphy, E. Angela, Hurley, Thomas G., Hébert, James R.

“…Background Enterolignans are important biomarkers of microbiota diversity, with higher levels indicating greater diversity. Diet and inflammation have been…”
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The Impact of Immune Cells on the Skeletal Muscle Microenvironment During Cancer Cachexia by VanderVeen, Brandon N, Murphy, E Angela, Carson, James A

“…Progressive weight loss combined with skeletal muscle atrophy, termed cachexia, is a common comorbidity associated with cancer that results in adverse…”
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Sucrose consumption alters steroid and dopamine signalling in the female rat brain by Tobiansky, Daniel J, Kachkovski, George V, Enos, Reilly T, Schmidt, Kim L, Murphy, E Angela, Soma, Kiran K

“…Sucrose consumption is associated with type 2 diabetes, cardiovascular disease, and cognitive deficits. Sucrose intake during pregnancy might have particularly…”
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Effective recruitment strategies for African-American men and women: the Nutritious Eating with Soul study by Turner-McGrievy, Gabrielle M, Wilson, Mary J, Bailey, Shiba, Bernhart, John A, Wilcox, Sara, Frongillo, Edward A, Murphy, E Angela, Hutto, Brent

“…Previous studies have found it challenging to recruit African-American (AA) participants into health education research studies. The goal of this article is to…”
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Impact of weight loss and partial weight regain on immune cell and inflammatory markers in adipose tissue in male mice by Sougiannis, Alexander T, VanderVeen, Brandon N, Cranford, Taryn L, Enos, Reilly T, Velazquez, Kandy T, McDonald, Sierra, Bader, Jackie E, Chatzistamou, Ioulia, Fan, Daping, Murphy, E Angela

“…Weight fluctuations are common among individuals with obesity and are associated with increased morbidity. We examined adipose tissue immune and inflammatory…”
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Therapeutic Potential of Emodin for Gastrointestinal Cancers by McDonald, Sierra J., VanderVeen, Brandon N., Velazquez, Kandy T., Enos, Reilly T., Fairman, Ciaran M., Cardaci, Thomas D., Fan, Daping, Murphy, E. Angela

“…Gastrointestinal (GI) cancers cause one-third of all cancer-related deaths worldwide. Natural compounds are emerging as alternative or adjuvant cancer…”
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TFEB is a master regulator of tumor-associated macrophages in breast cancer by Li, Yong, Hodge, Johnie, Liu, Qing, Wang, Junfeng, Wang, Yuzhen, Evans, Trent D, Altomare, Diego, Yao, Yongzhong, Murphy, E Angela, Razani, Babak, Fan, Daping

“…Tumor-associated macrophages (TAMs) play key roles in the development of many malignant solid tumors including breast cancer. They are educated in the tumor…”
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Quercetin Improved Muscle Mass and Mitochondrial Content in a Murine Model of Cancer and Chemotherapy-Induced Cachexia by VanderVeen, Brandon N, Cardaci, Thomas D, Cunningham, Patrice, McDonald, Sierra J, Bullard, Brooke M, Fan, Daping, Murphy, E Angela, Velázquez, Kandy T

“…A cachexia diagnosis is associated with a doubling in hospital stay and increased healthcare cost for cancer patients and most cachectic patients do not…”
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Influence of dietary saturated fat content on adiposity, macrophage behavior, inflammation, and metabolism: composition matters by Enos, Reilly T., Davis, J. Mark, Velázquez, Kandy T., McClellan, Jamie L., Day, Stani D., Carnevale, Kevin A., Murphy, E. Angela

“…We examined the effects of three high-fat diets (HFD), differing in the percentage of total calories from saturated fat (SF) (6%, 12%, and 24%) but identical…”
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The Acute Effects of 5 Fluorouracil on Skeletal Muscle Resident and Infiltrating Immune Cells in Mice by VanderVeen, Brandon N, Sougiannis, Alexander T, Velazquez, Kandy T, Carson, James A, Fan, Daping, Murphy, E Angela

“…5 fluorouracil (5FU) has been a first-choice chemotherapy drug for several cancer types (e.g., colon, breast, head, and neck); however, its efficacy is…”
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Obesity reduced survival with 5-fluorouracil and did not protect against chemotherapy-induced cachexia or immune cell cytotoxicity in mice by VanderVeen, Brandon N., Cardaci, Thomas D., McDonald, Sierra J., Madero, Sarah S., Unger, Christian A., Bullard, Brooke M., Enos, Reilly T., Velázquez, Kandy T., Kubinak, Jason L., Fan, Daping, Murphy, E. Angela

“…Fluorouracil/5-flourouracil (5FU) is a first-line chemotherapy drug for many cancer types; however, its associated toxicities contribute to poor quality of…”
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