Search Results - "Angel, C E"

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    Detailed characterisation of CB2 receptor protein expression in peripheral blood immune cells from healthy human volunteers using flow cytometry by Graham, E S, Angel, C E, Schwarcz, L E, Dunbar, P R, Glass, M

    “…It is commonly accepted from gene expression studies that the CB2 receptor is expressed by most cell types of the rodent and human immune system. However, the…”
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    P12.02 Glioblastoma Multiforme immunological blockades and the implications of glioma cancer stem cells by Robilliard, L D, MacDonald, C, Angel, C E, Finlay, G J, Joseph, W, Graham, E S

    Published in Neuro-oncology (Charlottesville, Va.) (06-09-2019)
    “…Abstract BACKGROUND Glioblastoma Multiforme (GBM) is classified as a WHO grade IV astrocytoma that continues to circumvent classical and novel chemo-, radio-…”
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    CD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts by Angel, Catherine E., Lala, Aisha, Chen, Chun-Jen J., Edgar, Stephen G., Ostrovsky, Lena L., Dunbar, P. Rod

    Published in International immunology (01-11-2007)
    “…We recently demonstrated that three antigen-presenting cell (APC) subsets exist in the healthy human dermis, CD14+ and CD1a+ dermal APCs and migratory dermal…”
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    4-N-, 4-S-, and 4-O-Chloroquine Analogues: Influence of Side Chain Length and Quinolyl Nitrogen pKa on Activity vs Chloroquine Resistant Malaria by NATARAJAN, Jayakumar K., ALUMASA, John N., YEARICK, Kimberly, EKOUE-KOVI, Kekeli A., CASABIANCA, Leah B., DE DIOS, Angel C., WOLF, Christian, ROEPE, Paul D.

    Published in Journal of medicinal chemistry (26-06-2008)
    “…Using predictions from heme-quinoline antimalarial complex structures, previous modifications of chloroquine (CQ), and hypotheses for chloroquine resistance…”
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    Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas by Ekoue-Kovi, Kekeli, Yearick, Kimberly, Iwaniuk, Daniel P., Natarajan, Jayakumar K., Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian

    Published in Bioorganic & medicinal chemistry (01-01-2009)
    “…More than 50 new chloroquine analogues exhibiting systematically varied side chains have been synthesized and tested against sensitive and resistant strains of…”
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    Overcoming Drug Resistance to Heme-Targeted Antimalarials by Systematic Side Chain Variation of 7-Chloro-4-aminoquinolines by Yearick, Kimberly, Ekoue-Kovi, Kekeli, Iwaniuk, Daniel P, Natarajan, Jayakumar K, Alumasa, John, de Dios, Angel C, Roepe, Paul D, Wolf, Christian

    Published in Journal of medicinal chemistry (10-04-2008)
    “…Systematic variation of the branching and basicity of the side chain of chloroquine yielded a series of new 7-chloro-4-aminoquinoline derivatives exhibiting…”
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    Solution Structures of Antimalarial Drug−Heme Complexes by Leed, Alison, DuBay, Kateri, Ursos, Lyann M. B, Sears, Devin, de Dios, Angel C, Roepe, Paul D

    Published in Biochemistry (Easton) (13-08-2002)
    “…Paramagnetic metal centers [such as FeIII found within ferriprotoporphyrin IX heme (FPIX)] exert through space effects on the relaxation rate of nearby proton…”
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    Neutrophil Influx and Chemokine Production during the Early Phases of the Antitumor Response to the Vascular Disrupting Agent DMXAA (ASA404) by Wang, Liang-Chuan S., Thomsen, Lotte, Sutherland, Rachel, Reddy, Charu B., Tijono, Sofian M., Chen, Chun-Jen J., Angel, Catherine E., Dunbar, P. Rod, Ching, Lai-Ming

    Published in Neoplasia (New York, N.Y.) (01-08-2009)
    “…5,6-Dimethylxanthenone-4-acetic acid (DMXAA) acts through tumor vascular disruption and cytokine production and is the first of its class to enter phase 3…”
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    Relationship between NMR Shielding and Heme Binding Strength for a Series of 7-Substituted Quinolines by Casabianca, Leah B, de Dios, Angel C

    “…Chemical shielding tensors are calculated for the carbons in a series of 4-aminoquinolines with different substituents at the 7-position. The σ11 component is…”
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    NMR Studies of Chloroquine−Ferriprotoporphyrin IX Complex by de Dios, Angel C, Tycko, Robert, Ursos, Lyann M. B, Roepe, Paul D

    “…By examining natural-abundance 13C and 15N solid-state nuclear magnetic resonance (NMR) spectra of acid-precipitated chloroquine−ferriprotoporphyrin IX…”
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    13C NMR Study of the Self-Association of Chloroquine, Amodiaquine, and Quinine by Casabianca, Leah B, de Dios, Angel C

    “…Experimental and calculated 13C NMR chemical shifts of quinoline ring carbons are used to investigate the self-association of the antimalarial drugs…”
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    Characterization of Polymorphs and Solid-State Reactions for Paramagnetic Systems by 13C Solid-State NMR and ab Initio Calculations by Shaibat, Medhat A, Casabianca, Leah B, Wickramasinghe, Nalinda P, Guggenheim, Stephen, de Dios, Angel C, Ishii, Yoshitaka

    Published in Journal of the American Chemical Society (12-09-2007)
    “…Despite its importance in drug and material science, spectroscopic characterization of polymorphs or supramolecular structures of paramagnetic systems often…”
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    Carbon Chemical Shift Tensor Components in Quinolines and Quinoline N-Oxides by Casabianca, Leah B, Faller, Caitlyn M, de Dios, Angel C

    “…Chemical shift calculations are carried out for the quinoline carbons in 1,8-bis(2-isopropyl-4-quinolyl)naphthalene, 2-isopropylquinoline, amodiaquine,…”
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    Cell Death Mechanisms Induced by Cytotoxic Lymphocytes by Chávez-galán, L, Arenas-del Angel, M C, Zenteno, E, Chávez, R, Lascurain, R

    Published in Cellular & molecular immunology (01-02-2009)
    “…One of the functions of the immune system is to recognize and destroy abnormal or infected cells to maintain homeostasis. This is accomplished by cytotoxic…”
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