Search Results - "Angèle, Chopard"

Muscle wasting and aging: Experimental models, fatty infiltrations, and prevention by Brioche, Thomas, Pagano, Allan F., Py, Guillaume, Chopard, Angèle

“…Identification of cost-effective interventions to maintain muscle mass, muscle strength, and physical performance during muscle wasting and aging is an…”
Get full text

Early structural and functional signature of 3‐day human skeletal muscle disuse using the dry immersion model by Demangel, Rémi, Treffel, Loïc, Py, Guillaume, Brioche, Thomas, Pagano, Allan F., Bareille, Marie‐Pierre, Beck, Arnaud, Pessemesse, Laurence, Candau, Robin, Gharib, Claude, Chopard, Angèle, Millet, Catherine

“…Key points Our study contributes to the characterization of muscle loss and weakness processes induced by a sedentary life style, chronic hypoactivity,…”
Get full text

The exerkine apelin reverses age-associated sarcopenia by Vinel, Claire, Lukjanenko, Laura, Batut, Aurelie, Deleruyelle, Simon, Pradère, Jean-Philippe, Le Gonidec, Sophie, Dortignac, Alizée, Geoffre, Nancy, Pereira, Ophelie, Karaz, Sonia, Lee, Umji, Camus, Mylène, Chaoui, Karima, Mouisel, Etienne, Bigot, Anne, Mouly, Vincent, Vigneau, Mathieu, Pagano, Allan F., Chopard, Angèle, Pillard, Fabien, Guyonnet, Sophie, Cesari, Matteo, Burlet-Schiltz, Odile, Pahor, Marco, Feige, Jerome N., Vellas, Bruno, Valet, Philippe, Dray, Cedric

“…Sarcopenia, the degenerative loss of skeletal muscle mass, quality and strength, lacks early diagnostic tools and new therapeutic strategies to prevent the…”
Get full text

Proteome-wide Adaptations of Mouse Skeletal Muscles during a Full Month in Space by Tascher, Georg, Brioche, Thomas, Maes, Pauline, Chopard, Angèle, O’Gorman, Donal, Gauquelin-Koch, Guillemette, Blanc, Stéphane, Bertile, Fabrice

“…The safety of space flight is challenged by a severe loss of skeletal muscle mass, strength, and endurance that may compromise the health and performance of…”
Get full text

Short‐term disuse promotes fatty acid infiltration into skeletal muscle by Pagano, Allan F., Brioche, Thomas, Arc‐Chagnaud, Coralie, Demangel, Rémi, Chopard, Angèle, Py, Guillaume

“…Background Many physiological and/or pathological conditions lead to muscle deconditioning, a well‐described phenomenon characterized by a loss of strength and…”
Get full text

Effects of hindlimb unloading and subsequent reloading on the structure and mechanical properties of Achilles tendon‐to‐bone attachment by Camy, Claire, Brioche, Thomas, Senni, Karim, Bertaud, Alexandrine, Genovesio, Cécile, Lamy, Edouard, Fovet, Théo, Chopard, Angèle, Pithioux, Martine, Roffino, Sandrine

“…While muscle and bone adaptations to deconditioning have been widely described, few studies have focused on the tendon enthesis. Our study examined the effects…”
Get full text

Ergothioneine Improves Aerobic Performance Without Any Negative Effect on Early Muscle Recovery Signaling in Response to Acute Exercise by Fovet, Théo, Guilhot, Corentin, Delobel, Pierre, Chopard, Angèle, Py, Guillaume, Brioche, Thomas

“…Physical activity is now recognized as an essential element of healthy lifestyles. However, intensive and repeated exercise practice produces a high level of…”
Get full text

Early Deconditioning of Human Skeletal Muscles and the Effects of a Thigh Cuff Countermeasure by Fovet, Théo, Guilhot, Corentin, Stevens, Laurence, Montel, Valérie, Delobel, Pierre, Roumanille, Rémi, Semporé, Michel-Yves, Freyssenet, Damien, Py, Guillaume, Brioche, Thomas, Chopard, Angèle

“…Muscle deconditioning is a major consequence of a wide range of conditions from spaceflight to a sedentary lifestyle, and occurs as a result of muscle…”
Get full text

Achilles tendon enthesis behavior under cyclic compressive loading: Consequences of unloading and early remobilization by Camy, Claire, Maurel-Pantel, Aurélien, Lallemand, Marylène, Fovet, Théo, Brioche, Thomas, Genovesio, Cécile, Chopard, Angèle, Pithioux, Martine, Roffino, Sandrine

“…The Achilles tendon enthesis (ATE) anchors the Achilles tendon into the calcaneus through fibrocartilaginous tissue. The latter is enriched in type II collagen…”
Get full text

Comprehensive assessment of physiological responses in women during the ESA dry immersion VIVALDI microgravity simulation by Robin, Adrien, Van Ombergen, Angelique, Laurens, Claire, Bergouignan, Audrey, Vico, Laurence, Linossier, Marie-Thérèse, Pavy-Le Traon, Anne, Kermorgant, Marc, Chopard, Angèle, Py, Guillaume, Green, David Andrew, Tipton, Michael, Choukér, Alexander, Denise, Pierre, Normand, Hervé, Blanc, Stéphane, Simon, Chantal, Rosnet, Elisabeth, Larcher, Françoise, Fernandez, Peter, de Glisezinski, Isabelle, Larrouy, Dominique, Harant-Farrugia, Isabelle, Antunes, Inês, Gauquelin-Koch, Guillemette, Bareille, Marie-Pierre, Billette De Villemeur, Rebecca, Custaud, Marc-Antoine, Navasiolava, Nastassia

“…Astronauts in microgravity experience multi-system deconditioning, impacting their inflight efficiency and inducing dysfunctions upon return to Earth gravity…”
Get full text

Does Physical Inactivity Induce Significant Changes in Human Gut Microbiota? New Answers Using the Dry Immersion Hypoactivity Model by Jollet, Maxence, Nay, Kevin, Chopard, Angèle, Bareille, Marie-Pierre, Beck, Arnaud, Ollendorff, Vincent, Vernus, Barbara, Bonnieu, Anne, Mariadassou, Mahendra, Rué, Olivier, Derbré, Frédéric, Goustard, Bénédicte, Koechlin-Ramonatxo, Christelle

“…Gut microbiota, a major contributor to human health, is influenced by physical activity and diet, and displays a functional cross-talk with skeletal muscle…”
Get full text

Evaluation of an Antioxidant and Anti-inflammatory Cocktail Against Human Hypoactivity-Induced Skeletal Muscle Deconditioning by Arc-Chagnaud, Coralie, Py, Guillaume, Fovet, Théo, Roumanille, Rémi, Demangel, Rémi, Pagano, Allan F, Delobel, Pierre, Blanc, Stéphane, Jasmin, Bernard J, Blottner, Dieter, Salanova, Michele, Gomez-Cabrera, Mari-Carmen, Viña, José, Brioche, Thomas, Chopard, Angèle

“…Understanding the molecular pathways involved in the loss of skeletal muscle mass and function induced by muscle disuse is a crucial issue in the context of…”
Get full text

Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable by Rudwill, Floriane, O’Gorman, Donal, Lefai, Etienne, Chery, Isabelle, Zahariev, Alexandre, Normand, Sylvie, Pagano, Allan F, Chopard, Angèle, Damiot, Anthony, Laurens, Claire, Hodson, Leanne, Canet-Soulas, Emmanuelle, Heer, Martina, Meuthen, Petra Frings, Buehlmeier, Judith, Baecker, Natalie, Meiller, Laure, Gauquelin-Koch, Guillemette, Blanc, Stéphane, Simon, Chantal, Bergouignan, Audrey

“…Abstract Context The effects of energy-balanced bed rest on metabolic flexibility have not been thoroughly examined. Objective We investigated the effects of…”
Get full text

Muscle Regeneration with Intermuscular Adipose Tissue (IMAT) Accumulation Is Modulated by Mechanical Constraints by Pagano, Allan F, Demangel, Rémi, Brioche, Thomas, Jublanc, Elodie, Bertrand-Gaday, Christelle, Candau, Robin, Dechesne, Claude A, Dani, Christian, Bonnieu, Anne, Py, Guillaume, Chopard, Angèle

“…Sports trauma are able to induce muscle injury with fibrosis and accumulation of intermuscular adipose tissue (IMAT), which affect muscle function. This study…”
Get full text

Towards human exploration of space: the THESEUS review series on muscle and bone research priorities by Lang, Thomas, Van Loon, Jack J.W.A., Bloomfield, Susan, Vico, Laurence, Chopard, Angele, Rittweger, Joern, Kyparos, Antonios, Blottner, Dieter, Vuori, Ilkka, Gerzer, Rupert, Cavanagh, Peter R.

“…Without effective countermeasures, the musculoskeletal system is altered by the microgravity environment of long-duration spaceflight, resulting in atrophy of…”
Get full text

Severe Muscle Deconditioning Triggers Early Extracellular Matrix Remodeling and Resident Stem Cell Differentiation into Adipocytes in Healthy Men by Guilhot, Corentin, Fovet, Théo, Delobel, Pierre, Dargegen, Manon, Jasmin, Bernard J, Brioche, Thomas, Chopard, Angèle, Py, Guillaume

“…Besides the loss of muscle mass and strength, increased intermuscular adipose tissue (IMAT) is now a well-recognized consequence of muscle deconditioning as…”
Get full text

A nutrient cocktail prevents lipid metabolism alterations induced by 20 days of daily steps reduction and fructose overfeeding: result from a randomized study by Damiot, Anthony, Demangel, Rémi, Noone, John, Chery, Isabelle, Zahariev, Alexandre, Normand, Sylvie, Brioche, Thomas, Crampes, François, de Glisezinski, Isabelle, Lefai, Etienne, Bareille, Marie Pierre, Chopard, Angèle, Drai, Jocelyne, Collin-Chavagnac, Delphine, Heer, Martina, Gauquelin-Koch, Guillemette, Prost, Michel, Simon, Patrick, Py, Guillaume, Blanc, Stéphane, Simon, Chantal, Bergouignan, Audrey, O'Gorman, Donal J

“…Physical inactivity and sedentary behaviors are independent risk factors for numerous diseases. We examined the ability of a nutrient cocktail composed of…”
Get full text

Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis and mechanical power in rats by Roumanille, Rémi, Vernus, Barbara, Brioche, Thomas, Descossy, Vincent, Van Ba, Christophe Tran, Campredon, Sarah, Philippe, Antony G, Delobel, Pierre, Bertrand-Gaday, Christelle, Chopard, Angèle, Bonnieu, Anne, Py, Guillaume, Fança-Berthon, Pascale

“…Background Owing to its strength-building and adaptogenic properties, Rhaponticum carthamoides (Rha) has been commonly used by elite Soviet and Russian…”
Get full text

Characterization of the mechanical properties of the mouse Achilles tendon enthesis by microindentation. Effects of unloading and subsequent reloading by Camy, Claire, Grünewald, Tilman, Lamy, Edouard, Roseren, Flavy, Caumes, Mathieu, Fovet, Théo, Brioche, Thomas, Genovesio, Cecile, Chopard, Angèle, Pithioux, Martine, Roffino, Sandrine

“…The fibrocartilaginous tendon enthesis, i.e. the site where a tendon is attached to bone through a fibrocartilaginous tissue, is considered as a functionally…”
Get full text

Molecular events and signalling pathways involved in skeletal muscle disuse‐induced atrophy and the impact of countermeasures by Chopard, Angèle, Hillock, Steven, Jasmin, Bernard J.

“…•  Introduction •  Overview of signalling pathways involved in disuse‐induced muscle atrophy ‐  Changes in protein synthesis and associated signalling pathways…”
Get full text