Search Results - "Ang, Mei‐Kim"

Randomized trial comparing surgery and adjuvant radiotherapy versus concurrent chemoradiotherapy in patients with advanced, nonmetastatic squamous cell carcinoma of the head and neck: 10‐year update and subset analysis by Iyer, N. Gopalakrishna, Tan, Daniel S.W., Tan, Veronique KM, Wang, Weining, Hwang, Jacqueline, Tan, Ngian‐Chye, Sivanandan, Ranjiv, Tan, Hiang‐Khoon, Lim, Wan Teck, Ang, Mei‐Kim, Wee, Joseph, Soo, Khee‐Chee, Tan, Eng Huat

“…BACKGROUND The current study was performed to report the long‐term results of a trial comparing concurrent chemotherapy and radiotherapy (CCRT) with surgery…”
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Concurrent Chemo-Radiation With or Without Induction Gemcitabine, Carboplatin, and Paclitaxel: A Randomized, Phase 2/3 Trial in Locally Advanced Nasopharyngeal Carcinoma by Tan, Terence, FRCR, Lim, Wan-Teck, MRCP, Fong, Kam-Weng, FRCR, Cheah, Shie-Lee, FRCR, Soong, Yoke-Lim, FRCR, Ang, Mei-Kim, MRCP, Ng, Quan-Sing, MRCP, Tan, Daniel, MRCP, Ong, Whee-Sze, MAppStats, Tan, Sze-Huey, MSc, Yip, Connie, FRCR, Quah, Daniel, FRCR, Soo, Khee-Chee, MD, Wee, Joseph, FRCR

“…Purpose To compare survival, tumor control, toxicities, and quality of life of patients with locally advanced nasopharyngeal carcinoma (NPC) treated with…”
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Detection of circulating tumor DNA with ultradeep sequencing of plasma cell‐free DNA for monitoring minimal residual disease and early detection of recurrence in early‐stage lung cancer by Tan, Aaron C., Lai, Gillianne G. Y., Saw, Stephanie P. L., Chua, Kevin L. M., Takano, Angela, Ong, Boon‐Hean, Koh, Tina P. T., Jain, Amit, Tan, Wan Ling, Ng, Quan Sing, Kanesvaran, Ravindran, Rajasekaran, Tanujaa, Kalashnikova, Ekaterina, Renner, Derrick, Sudhaman, Sumedha, Malhotra, Meenakshi, Sethi, Himanshu, Liu, Minetta C., Aleshin, Alexey, Lim, Wan‐Teck, Tan, Eng‐Huat, Skanderup, Anders J., Ang, Mei‐Kim, Tan, Daniel S. W.

“…Background In early‐stage non–small cell lung cancer (NSCLC), recurrence is frequently observed. Circulating tumor DNA (ctDNA) has emerged as a noninvasive…”
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Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and cost-effectiveness analysis by Tan, Aaron C., Lai, Gillianne G.Y., Tan, Gek San, Poon, Shou Yu, Doble, Brett, Lim, Tse Hui, Aung, Zaw Win, Takano, Angela, Tan, Wan Ling, Ang, Mei-Kim, Tan, Bien Soo, Devanand, Anantham, Too, Chow Wei, Gogna, Apoorva, Ong, Boon-Hean, Koh, Tina P.T., Kanesvaran, Ravindran, Ng, Quan Sing, Jain, Amit, Rajasekaran, Tanujaa, Lim, Alvin S.T., Lim, Wan Teck, Toh, Chee Keong, Tan, Eng-Huat, Lim, Tony Kiat Hon, Tan, Daniel S.W.

“…•Upfront NGS is feasible and cost-effective in an EGFR mutant predominant population.•Characterizing the wider genomic profile may yield important…”
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Twenty‐five years of Respirology: Advances in lung cancer by Ang, Mei‐Kim, Mok, Tony S.K.

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Phase II study of nimotuzumab (TheraCim‐hR3) concurrent with cisplatin/radiotherapy in patients with locally advanced head and neck squamous cell carcinoma by Ang, Mei‐Kim, Montoya, Jose Enrique, Tharavichitkul, Ekkasit, Lim, Cindy, Tan, Terence, Wang, Lan Ying, Wee, Joseph, Soong, Yoke‐Lim, Fong, Kam‐Weng, Ng, Quan Sing, Tan, Daniel Shao‐Weng, Toh, Chee‐Keong, Tan, Eng‐Huat, Lim, Wan‐Teck

“…Background The efficacy of a combination of nimotuzumab, a humanized monoclonal antibody to the epidermal growth factor receptor, with chemoradiation in…”
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Adjuvant Immunotherapy in Patients with Early-Stage Non-small Cell Lung Cancer and Future Directions by Saw, Stephanie PL, Ang, Mei-Kim, Tan, Daniel SW

“…Opinion statement While cisplatin-based adjuvant chemotherapy has been the standard of care for the past two decades, the recent introduction of immunotherapy…”
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PD-L1 score as a prognostic biomarker in asian early-stage epidermal growth factor receptor-mutated lung cancer by Saw, Stephanie P.L., Ng, Win Pin, Zhou, Siqin, Lai, Gillianne G.Y., Tan, Aaron C., Ang, Mei-Kim, Lim, Wan-Teck, Kanesvaran, Ravindran, Ng, Quan Sing, Jain, Amit, Tan, Wan Ling, Rajasekaran, Tanujaa, Chan, Johan W.K., Teh, Yi Lin, Pang, Mengyuan, Yeo, Jia-Chi, Takano, Angela, Ong, Boon-Hean, Tan, Eng-Huat, Tan, Sze Huey, Skanderup, Anders J., Tan, Daniel S.W.

“…To determine the prognostic value of programmed death-ligand 1 (PD-L1) score in early-stage epidermal growth factor receptor (EGFR)-mutated non-small cell lung…”
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Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases by Tan, Wan-Ling, Ng, Quan Sing, Lim, Cindy, Tan, Eng Huat, Toh, Chee Keong, Ang, Mei-Kim, Kanesvaran, Ravindran, Jain, Amit, Tan, Daniel S W, Lim, Darren Wan-Teck

“…Afatinib is an oral irreversible epidermal growth factor receptor (EGFR) tyrosine-kinase inhibitor (TKI) indicated in first-line treatment of advanced…”
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Clinical efficacy and biomarker analysis of dual PD-1/CTLA-4 blockade in recurrent/metastatic EBV-associated nasopharyngeal carcinoma by Lim, Darren Wan-Teck, Kao, Hsiang-Fong, Suteja, Lisda, Li, Constance H., Quah, Hong Sheng, Tan, Daniel Shao-Weng, Tan, Sze-Huey, Tan, Eng-Huat, Tan, Wan-Ling, Lee, Justina Nadia, Wee, Felicia Yu-Ting, Jain, Amit, Goh, Boon-Cher, Chua, Melvin L. K., Liao, Bin-Chi, Ng, Quan Sing, Hong, Ruey-Long, Ang, Mei-Kim, Yeong, Joe Poh-Sheng, Iyer, N. Gopalakrishna

“…Single-agent checkpoint inhibitor (CPI) activity in Epstein-Barr Virus (EBV) related nasopharyngeal carcinoma (NPC) is limited. Dual CPI shows increased…”
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Intertumor heterogeneity of non‐small‐cell lung carcinomas revealed by multiplexed mutation profiling and integrative genomics by Tan, Daniel S.W., Camilleri‐Broët, Sophie, Tan, Eng Huat, Alifano, Marco, Lim, Wan‐Teck, Bobbio, Antonio, Zhang, Shenli, Ng, Quan‐Sing, Ang, Mei‐Kim, Iyer, N. Gopalakrishna, Takano, Angela, Lim, Kiat Hon, Régnard, Jean‐François, Tan, Patrick, Broët, Philippe

“…Non‐small‐cell lung cancer (NSCLC) is a heterogeneous disease, with a burden of genomic alterations exceeding most other tumors. The goal of our study was to…”
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Association of Clinicopathologic and Molecular Tumor Features With Recurrence in Resected Early-Stage Epidermal Growth Factor Receptor-Positive Non-Small Cell Lung Cancer by Saw, Stephanie P L, Zhou, Siqin, Chen, Jianbin, Lai, Gillianne, Ang, Mei-Kim, Chua, Kevin, Kanesvaran, Ravindran, Ng, Quan Sing, Jain, Amit, Tan, Wan Ling, Rajasekaran, Tanujaa, Lim, Darren W T, Tan, Aaron, Fong, Kam Weng, Takano, Angela, Cheng, Xin Ming, Lim, Kiat Hon, Koh, Tina, Ong, Boon-Hean, Tan, Eng Huat, Toh, Chee Keong, Skanderup, Anders J, Tan, Sze Huey, Tan, Daniel S W

“…The recently published ADAURA study has posed a significant dilemma for clinicians in selecting patients for adjuvant osimertinib. Risk factors for recurrence…”
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Combinatorial Hypofractionated Radiotherapy and Pembrolizumab in Anaplastic Thyroid Cancer by Tan, Janice Ser Huey, Tay, Timothy Kwang Yong, Ong, Enya Hui Wen, Fehlings, Michael, Tan, Daniel Shao-Weng, Sukma, Nadiah Binte, Chen, Eileen Xueqin, Sng, Jen-Hwei, Yip, Connie Siew Poh, Lim, Kok Hing, Lim, Darren Wan-Teck, Iyer, Narayanan Gopalakrishna, Hwang, Jacqueline Siok Gek, Chua, Melvin Lee Kiang, Ang, Mei-Kim

“…Objectives Anaplastic thyroid cancer (ATC) is an aggressive disease associated with poor outcomes and resistance to therapies. Our study aim was to evaluate…”
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Outcomes and Prognostic Factors of Radiation-Induced and De Novo Head and Neck Squamous Cell Carcinomas by Tay, Gerald Ci-An, Iyer, N. Gopalakrishna, Ong, Whee-Sze, Tai, David, Ang, Mei-Kim, Ha, Tam Cam, Soo, Khee-Chee, Tan, Hiang Khoon

“…Objective We sought to compare clinical outcomes, pathological features, treatment patterns, and survival outcomes between radiation-induced squamous cell…”
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Correction to: Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases by Tan, Wan-Ling, Ng, Quan Sing, Lim, Cindy, Tan, Eng Huat, Toh, Chee Keong, Ang, Mei-Kim, Kanesvaran, Ravindran, Jain, Amit, Tan, Daniel S W, Lim, Darren Wan-Teck

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Imaging features of renal complications after crizotinib treatment for non–small-cell lung cancer: a case report by Chan, Wan Ying, MBBS, Ang, Mei-Kim, MRCP, Tan, Daniel Shao Weng, MRCP, Koh, Wan Lin, FRCR, Kwek, Jin Wei, FRCR

“…Abstract Crizotinib has been approved for the treatment of advanced ALK-positive non–small cell lung cancer. Its use is associated with the development of…”
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Interactions between clinical factors, p16, and cyclin-D1 expression and survival outcomes in oropharyngeal and hypopharyngeal squamous cell carcinoma by Ang, Siok-Hoon, Haaland, Benjamin, Acharyya, Sanchalika, Thu, Minn M. M., Krisna, Sai-Sakktee, Hwang, Siok-Gek, Tan, Puay-Hoon, Ng, Quan-Sing, Tan, Daniel S. W., Tai, Wai-Meng, Tan, Eng-Huat, Lim, Wan-Teck, Ang, Mei-Kim

“…Background P16 and cyclin‐D1 are cell cycle proteins commonly dysregulated in head and neck carcinoma. We assessed their expression, clinicopathological…”
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ERCC1 Protein Expression Is Associated with Differential Survival in Oropharyngeal Head and Neck Squamous Cell Carcinoma by Patel, Mihir R., Zhao, Ni, Ang, Mei-Kim, Stadler, Michael E., Fritchie, Karen, Weissler, Mark C., Zanation, Adam M., Harris, Stephen L., Funkhouser, William K., Olshan, Andrew F., Shores, Carol G., Hayes, D. Neil

“…Objective To investigate ERCC1 protein expression and its relationship to clinical factors and treatment outcomes in patients with head and neck squamous cell…”
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Comparative analysis of extra-nodal NK/T-cell lymphoma and peripheral T-cell lymphoma: significant differences in clinical characteristics and prognosis by Lim, Soon Thye, Hee, Siew Wan, Quek, Richard, Lim, Lay Cheng, Yap, Swee Peng, Loong, Er-Li, Sng, Ivy, Tan, Leonard Hwan-Cheong, Ang, Mei-Kim, Ngeow, Joanne, Tham, Chee-Kian, Ngo, Lynette, Tan, Min Han, Tao, Miriam

“…Aim: We aimed to compare the frequencies, clinical characteristics, and prognostic factors of peripheral T‐cell lymphoma (PTCL) vs. extra‐nodal natural killer…”
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Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma by Tan, Daniel S W, Chong, Fui Teen, Leong, Hui Sun, Toh, Shen Yon, Lau, Dawn P, Kwang, Xue Lin, Zhang, Xiaoqian, Sundaram, Gopinath M, Tan, Gek San, Chang, Mei Mei, Chua, Boon Tin, Lim, Wan Teck, Tan, Eng Huat, Ang, Mei Kim, Lim, Tony K H, Sampath, Prabha, Chowbay, Balram, Skanderup, Anders J, DasGupta, Ramanuj, Iyer, N Gopalakrishna

“…A silent single-nucleotide variant (SNV) affecting the transcription of a long noncoding RNA (lncRNA EGFR-AS1) within the EGFR coding region alters the EGFR…”
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