Search Results - "Ang, Hwee Ting"

Scope and Mechanism of a True Organocatalytic Beckmann Rearrangement with a Boronic Acid/Perfluoropinacol System under Ambient Conditions by Mo, Xiaobin, Morgan, Timothy D. R, Ang, Hwee Ting, Hall, Dennis G

“…Catalytic activation of hydroxyl functionalities is of great interest for the production of pharmaceuticals and commodity chemicals. Here, 2-alkoxycarbonyl-…”
Get full text

Strain-Release-Driven Electrochemical Skeletal Rearrangement of Non-Biased Alkyl Cyclopropanes/butanes by Qi, Jing, Wang, Chu, Wang, Gan, O'Neill, Patrick, Dubbaka, Srinivas Reddy, Ang, Hwee Ting, Chen, Xuebo, Wu, Jie

“…Capitalizing the inherent strain energy within molecules, strain-release-driven reactions have been widely employed in organic synthesis. Small cycloalkanes…”
Get full text

Advanced In-Line Purification Technologies in Multistep Continuous Flow Pharmaceutical Synthesis by Lei, Zhexuan, Ang, Hwee Ting, Wu, Jie

“…Continuous flow synthesis is a widely used method for synthesizing fine chemicals due to its benefits such as process intensification, improved…”
Get full text

Modular and Practical 1,2‐Aryl(Alkenyl) Heteroatom Functionalization of Alkenes through Iron/Photoredox Dual Catalysis by Zhang, Weigang, Liu, Tao, Ang, Hwee Ting, Luo, Penghao, Lei, Zhexuan, Luo, Xiaohua, Koh, Ming Joo, Wu, Jie

“…Abstract Efficient methods for synthesizing 1,2‐aryl(alkenyl) heteroatomic cores, encompassing heteroatoms such as nitrogen, oxygen, sulfur, and halogens, are…”
Get full text

Photocatalytic Reductive Functionalization of Aryl Alkynes via Alkyne Radical Anions by Tong, Xiaogang, Wu, Zugen, Ang, Hwee Ting, Miao, Yidan, Lu, Yixin, Wu, Jie

“…The direct reductive functionalization of alkynes under mild conditions presents a promising yet challenging avenue for accessing value-added molecules. Alkyne…”
Get full text

Electrophotochemical Synthesis Facilitated Trifluoromethylation of Arenes Using Trifluoroacetic Acid by Qi, Jing, Xu, Jinhui, Ang, Hwee Ting, Wang, Bingbing, Gupta, Nipun Kumar, Dubbaka, Srinivas Reddy, O’Neill, Patrick, Mao, Xianwen, Lum, Yanwei, Wu, Jie

“…The trifluoromethyl (CF3) group is an essential moiety in medicinal chemistry due to its unique physicochemical properties. While trifluoroacetic acid (TFA) is…”
Get full text

Enantioselective Desymmetrization of 2‑Aryl-1,3-propanediols by Direct O‑Alkylation with a Rationally Designed Chiral Hemiboronic Acid Catalyst That Mitigates Substrate Conformational Poisoning by Estrada, Carl D, Ang, Hwee Ting, Vetter, Kim-Marie, Ponich, Ashley A, Hall, Dennis G

“…Enantioselective desymmetrization by direct monofunctionalization of prochiral diols is a powerful strategy to prepare valuable synthetic intermediates in high…”
Get full text

Unraveling the Silent Hydrolysis of Cyclic B–X/CC Isosteres: The Striking Impact of a Single Heteroatom on the Aromatic, Acidic, and Dynamic Properties of Hemiboronic Phenanthroids by Ang, Hwee Ting, Ponich, Ashley A., Paladino, Marco, Miskolzie, Mark, Hall, Dennis G.

“…Although heterocyclic hemiboronic acids are represented in several recently approved drugs, many questions remain unanswered regarding the physical properties…”
Get full text

Pyridine N-oxides as hydrogen atom transfer reagents for site-selective photoinduced C(sp3)–H functionalization by Ang, Hwee Ting, Miao, Yidan, Ravelli, Davide, Wu, Jie

Get full text

1,2,3-Triazole Synthesis: Development of Safe and Effective Batch and Continuous Manufacturing Processes by Song, Lei, Ang, Hwee Ting, Senthilperumal, Jagadeesan, Kanusu, Umamaheswara Rao, Venugopal, Sivasankaran, Rangarajan, Naveen, Krishnamoorthy, Shivasankar, Dubbaka, Srinivas Reddy, O’Neill, Patrick, Wu, Jie

“…In this paper, we present the development of a safe water-based synthesis of 1,2,3-triazole using cheap raw materials. Starting from glyoxal and hydrazine, a…”
Get full text

Enhanced Reactivity of Acridinium Perchlorate: Harnessing Redox Mediators for Trace Chloride Activation in Hydrogen Atom Transfer Photocatalysis by Wu, Mingyue, Wu, Zugen, Ang, Hwee Ting, Wang, Bing, Liu, Tao, Wu, Shaofei, Lei, Zhexuan, Liaw, Ming Wai, Chanmungkalakul, Supphachok, Lee, Chi-Lik Ken, Liu, Xiaogang, Lu, Yixin, Wu, Jie

“…Acridinium perchlorates and tetrafluoroborates are commonly employed photocatalysts with similar photophysical characteristics. Nevertheless, perchlorate salts…”
Get full text

Button-Push On-Demand Synthesis for Rapid Optimization of Antiviral Peptidomimetics by Tian, Duanshuai, Tan, Ting Wei, Kuan Hai, Ronald Toh, Wang, Gan, Mohamed, Fadhil Peer, Yu, Zhenyang, Ang, Hwee Ting, Xu, Weijun, Tan, Qian Wen, Ng, Pearly Shuyi, Low, Choon Heng, Liu, Boping, Quek Zekui, Perlyn, Joy, Joma Kanikadu, Cherian, Joseph, Mak, Frankie S, Wu, Jie

“…The optimization of hit compounds into drug candidates is a pivotal phase in drug discovery but often hampered by cumbersome manual synthesis of derivatives…”
Get full text

Lewis or Brønsted? A Rectification of the Acidic and Aromatic Nature of Boranol-Containing Naphthoid Heterocycles by Kazmi, M. Zain H, Rygus, Jason P. G, Ang, Hwee Ting, Paladino, Marco, Johnson, Matthew A, Ferguson, Michael J, Hall, Dennis G

“…Boron-containing heterocycles are important in a variety of applications from drug discovery to materials science; therefore a clear understanding of their…”
Get full text

Strain‐Release‐Driven Electrochemical Skeletal Rearrangement of Non‐Biased Alkyl Cyclopropanes/Butanes by Qi, Jing, Wang, Chu, Wang, Gan, O'Neill, Patrick, Reddy Dubbaka, Srinivas, Ting Ang, Hwee, Chen, Xuebo, Wu, Jie

“…Abstract Capitalizing the inherent strain energy within molecules, strain‐release‐driven reactions have been widely employed in organic synthesis. Small…”
Get full text

Catalytic photoactivation of a triarylamine electron donor-acceptor complex for difunctionalization of alkenes by Wu, Hao-Yan, Tang, Xiaodong, Guo, Ran, Ang, Hwee Ting, Nie, Jing, Wu, Jie, Ma, Jun-An, Zhang, Fa-Guang

“…The photoactivation of electron donor-acceptor complexes is a useful tool for the generation of radical species in synthetic chemistry. However, alkene…”
Get full text

Modular and Practical 1,2‐Aryl(Alkenyl) Heteroatom Functionalization of Alkenes through Iron/Photoredox Dual Catalysis by Zhang, Weigang, Liu, Tao, Ang, Hwee Ting, Luo, Penghao, Lei, Zhexuan, Luo, Xiaohua, Koh, Ming Joo, Wu, Jie

“…Abstract Efficient methods for synthesizing 1,2‐aryl(alkenyl) heteroatomic cores, encompassing heteroatoms such as nitrogen, oxygen, sulfur, and halogens, are…”
Get full text

Mechano-photoexcitation for organic synthesis using mechanoluminescent materials as photon sources by Xin, Xiaohua, Geng, Jinxing, Zhang, Duo, Ang, Hwee Ting, Wang, Hui, Cheng, Yongliang, Liu, Yun, Toh, Ren Wei, Wu, Jie, Wang, Han

Get full text