Search Results - "Ang, Desmond K. Y."

Molecular Pathogenesis of Infections Caused by Legionella pneumophila by Newton, Hayley J, Ang, Desmond K Y, van Driel, Ian R, Hartland, Elizabeth L

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

A convenient model of severe, high incidence autoimmune gastritis caused by polyclonal effector T cells and without perturbation of regulatory T cells by Tu, Eric, Ang, Desmond K Y, Hogan, Thea V, Read, Simon, Chia, Cheryl P Z, Gleeson, Paul A, van Driel, Ian R

“…Autoimmune gastritis results from the breakdown of T cell tolerance to the gastric H(+)/K(+) ATPase. The gastric H(+)/K(+) ATPase is responsible for the…”
Get full text

Role of regulatory T cells in gastrointestinal inflammatory disease by Van Driel, Ian R, Ang, Desmond KY

“…Regulatory T cells curb unwanted immune responses and regulate responses to microflora and it is now clear that regulatory T cells play an important role in a…”
Get full text

Two genetic loci independently confer susceptibility to autoimmune gastritis by Ang, Desmond K. Y., Brodnicki, Thomas C., Jordan, Margaret A., Wilson, Wendy E., Silveira, Pablo, Gliddon, Briony L., Baxter, Alan G., van Driel, Ian R.

“…Autoimmune gastritis is a CD4+ T cell-mediated disease induced in genetically susceptible mice by thymectomy on the third day after birth. Previous linkage…”
Get full text

Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport by Houghton, Fiona J., Bellingham, Shayne A., Hill, Andrew F., Bourges, Dorothée, Ang, Desmond K.Y., Gemetzis, Timothy, Gasnereau, Isabelle, Gleeson, Paul A.

“…Regulation of membrane transport is controlled by small G proteins, which include members of the Rab and Arf families. Whereas the role of the classic Arf…”
Get full text

Pathogenic T cells persist after reversal of autoimmune disease by immunosuppression with regulatory T cells by Tu, Eric, Bourges, Dorothée, Gleeson, Paul A., Ang, Desmond K. Y., Driel, Ian R.

“…Autoimmune disease can be prevented with immunosuppressive agents; however, the effectiveness of these treatments in advanced stage of disease and the fate of…”
Get full text

Both IFN‐γ and IL‐17 are required for the development of severe autoimmune gastritis by Tu, Eric, Ang, Desmond K.Y., Bellingham, Shayne A., Hogan, Thea V., Teng, Michele W. L., Smyth, Mark J., Hill, Andrew F., van Driel, Ian R.

“…IL‐17, produced by a distinct lineage of CD4+ helper T (Th) cells termed Th17 cells, induces the production of pro‐inflammatory cytokines from resident cells…”
Get full text

Cutting edge: pulmonary Legionella pneumophila is controlled by plasmacytoid dendritic cells but not type I IFN by Ang, Desmond K Y, Oates, Clare V L, Schuelein, Ralf, Kelly, Michelle, Sansom, Fiona M, Bourges, Dorothée, Boon, Louis, Hertzog, Paul J, Hartland, Elizabeth L, van Driel, Ian R

“…Plasmacytoid dendritic cells (pDCs) are well known as the major cell type that secretes type I IFN in response to viral infections. Their role in combating…”
Get full text

Immune Control of Legionella Infection: An in vivo Perspective by Schuelein, Ralf, Ang, Desmond K Y, van Driel, Ian R, Hartland, Elizabeth L

“…Legionella pneumophila is an intracellular pathogen that replicates within alveolar macrophages. Through its ability to activate multiple host innate immune…”
Get full text

Extrathymic mechanisms of T cell tolerance: Lessons from autoimmune gastritis by Hogan, Thea V, Ang, Desmond K.Y, Gleeson, Paul A, van Driel, Ian R

“…Abstract While the thymus plays a key role in the prevention of many autoimmune phenomena it is clear that robust mechanisms external to the thymus are also…”
Get full text

Extrathymic mechanisms of T cell tolerance : Lessons from autoimmune gastritis: Mechanisms of Autoimmunity: A Tribute to Professor Ian Mackay by HOGAN, Thea V, ANG, Desmond K. Y, GLEESON, Paul A, VAN DRIEL, Ian R

Get full text

Both IFN-[gamma] and IL-17 are required for the development of severe autoimmune gastritis by Tu, Eric, Ang, Desmond KY, Bellingham, Shayne A, Hogan, Thea V, Teng, Michele W L, Smyth, Mark J, Hill, Andrew F, van Driel, Ian R

“…IL-17, produced by a distinct lineage of CD4+ helper T (Th) cells termed Th17 cells, induces the production of pro-inflammatory cytokines from resident cells…”
Get full text