Search Results - "Ang, C. S."

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial by Noman, Awsan, MB, Ang, Donald SC, MD, Ogston, Simon, PhD, Lang, Chim C, Prof, Struthers, Allan D, Prof

“…Summary Background Experimental evidence suggests that xanthine oxidase inhibitors can reduce myocardial oxygen consumption for a particular stroke volume. If…”
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Efficacy and Safety of Lapatinib As First-Line Therapy for ErbB2-Amplified Locally Advanced or Metastatic Breast Cancer by GOMEZ, Henry L, DOVAL, Dinesh C, CASEY, Michelle A, BERGER, Mark S, STEIN, Steven H, SLEDGE, George W, CHAVEZ, Miguel A, ANG, Peter C. S, AZIZ, Zeba, NAG, Shona, NG, Christina, FRANCO, Sandra X, CHOW, Louis W. C, ARBUSHITES, Michael C

“…This study (EGF20009) assessed the efficacy and tolerability of two lapatinib administration schedules as first-line monotherapy in women with ErbB2-amplified…”
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Oxidative stress in renal dysfunction: mechanisms, clinical sequelae and therapeutic options by Kao, M P C, Ang, D S C, Pall, A, Struthers, A D

“…Oxidative stress has been increasingly linked to the high incidence of cardiovascular events in patients with chronic kidney disease (CKD), especially as…”
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Prenatal Exposure to Ultrasound Waves Impacts Neuronal Migration in Mice by Ang, Eugenius S. B. C., Gluncic, Vicko, Duque, Alvaro, Schafer, Mark E., Rakic, Pasko

“…Neurons of the cerebral neocortex in mammals, including humans, are generated during fetal life in the proliferative zones and then migrate to their final…”
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Four-Dimensional Migratory Coordinates of GABAergic Interneurons in the Developing Mouse Cortex by Ang, Eugenius S. B. C., Jr, Haydar, Tarik F, Gluncic, Vicko, Rakic, Pasko

“…We have used time-lapse multiphoton microscopy to map the migration and settling pattern of GABAergic interneurons that originate in the ganglionic eminence of…”
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CBR1 and CBR3 pharmacogenetics and their influence on doxorubicin disposition in Asian breast cancer patients by Lal, Suman, Sandanaraj, Edwin, Wong, Zee Wan, Ang, Peter C.S., Wong, Nan Soon, Lee, Edmund J.D., Chowbay, Balram

“…The present study aimed to identify polymorphic genes encoding carbonyl reductases (CBR1, CBR3) and investigate their influence on doxorubicin disposition in…”
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The prognostic significance of early and late anaemia in acute coronary syndrome by ANG, Donald S. C, KAO, Michelle P. C, NOMAN, A, LANG, C. C, STRUTHERS, A. D

“…Anaemia in acute coronary syndrome (ACS) is a common and strong independent risk factor but it is unknown whether early anaemia is transient or whether it…”
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The prognostic value of the ECG in hypertension: where are we now? by Ang, D S C, Lang, C C

“…In hypertension, the presence of left ventricular hypertrophy (LVH) is associated with increased risk of both cardiovascular morbidity and mortality. To date,…”
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Serial changes in adiponectin and BNP in ACS patients: paradoxical associations with each other and with prognosis by Ang, Donald S C, Welsh, Paul, Watt, Pauline, Nelson, Scott M, Struthers, Allan, Sattar, Naveed

“…Plasma adiponectin is inversely associated with the risk of coronary heart disease in healthy people. However, adiponectin and BNP (B-type natriuretic peptide)…”
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Phase I pharmacokinetic study of a weekly liposomal paclitaxel formulation (Genexol®-PM) in patients with solid tumors by Lim, W.T., Tan, E.H., Toh, C.K., Hee, S.W., Leong, S.S., Ang, P.C.S., Wong, N.S., Chowbay, B.

“…The aim of this study was to determine the maximum tolerated dose (MTD) and the pharmacokinetic profile of Genexol-PM in Asian cancer patients. Patients (N=24)…”
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Serial bedside B-type natriuretic peptide strongly predicts prognosis in acute coronary syndrome independent of echocardiographic abnormalities by Ang, Donald S.C., MD, MRCP, Kong, Colin F.J., MBChB, Kao, Michelle P.C., MBChB, MRCP, Struthers, Allan D., MD, FRCP

“…Background Elevated levels of B-type natriuretic peptide (BNP) are associated with adverse clinical outcomes in acute coronary syndrome (ACS), but several…”
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Final results of the double-blind placebo-controlled randomized phase 2 LOTUS trial of first-line ipatasertib plus paclitaxel for inoperable locally advanced/metastatic triple-negative breast cancer by Dent, Rebecca, Oliveira, Mafalda, Isakoff, Steven J., Im, Seock-Ah, Espié, Marc, Blau, Sibel, Tan, Antoinette R., Saura, Cristina, Wongchenko, Matthew J., Xu, Na, Bradley, Denise, Reilly, Sarah-Jayne, Mani, Aruna, Kim, Sung-Bae

“…Purpose In LOTUS (NCT02162719), adding the oral AKT inhibitor ipatasertib to first-line paclitaxel for locally advanced/metastatic triple-negative breast…”
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Mass Spectrometry-Based Analysis for the Discovery and Validation of Potential Colorectal Cancer Stool Biomarkers by Ang, C S, Baker, M S, Nice, E C

“…Colorectal cancer (CRC) is the third leading cause of cancer mortality for both men and women, and the second leading cause of cancer death for men and women…”
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The prognostic value of high sensitivity troponin T 7 weeks after an acute coronary syndrome by Ang, Donald S C, Kao, Michelle P C, Dow, Ellie, Lang, Chim, Struthers, Allan

“…The role of high sensitivity troponin T (hs-TnT) in the convalescence phase after an acute coronary syndrome (ACS) is unknown. The authors aim to assess the…”
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A comparison between B-type natriuretic peptide, global registry of acute coronary events (GRACE) score and their combination in ACS risk stratification by Ang, D S C, Wei, L, Kao, M P C, Lang, C C, Struthers, A D

“…In acute coronary syndrome (ACS), both the Global Registry of Acute Coronary Events (GRACE) score and B-type natriuretic peptide (BNP) predict cardiovascular…”
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The electrocardiogram is an unreliable method of identifying left ventricular hypertrophy in stable, treated angina patients by Ang, D S C, Ti, L L, Struthers, A D

“…In coronary artery disease (CAD), a potentially reversible factor leading to cardiac death is left ventricular hypertrophy (LVH). While the electrocardiogram…”
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Extracellular Vesicles From the Cotton Pathogen Fusarium oxysporum f. sp. vasinfectum Induce a Phytotoxic Response in Plants by Bleackley, Mark R, Samuel, Monisha, Garcia-Ceron, Donovan, McKenna, James A, Lowe, Rohan G T, Pathan, Mohashin, Zhao, Kening, Ang, Ching-Seng, Mathivanan, Suresh, Anderson, Marilyn A

“…Extracellular vesicles (EVs) represent a system for the coordinated secretion of a variety of molecular cargo including proteins, lipids, nucleic acids, and…”
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Left ventricular hypertrophy is present in one-half of newly-diagnosed peripheral arterial disease patients by Wright, Gary A, Ang, Donald SC, Stonebridge, Peter A, Belch, Jill JF, Struthers, Allan D

“…OBJECTIVESPeripheral arterial disease (PAD) patients are at high risk of cardiac death. Coincidental but silent coronary disease is obviously a major…”
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CT and MRI of primary and metastatic fibrolamellar carcinoma: a case series of 37 patients by Do, R K G, McErlean, A, Ang, C S, DeMatteo, R P, Abou-Alfa, G K

“…Fibrolamellar carcinoma (FLC) is a rare disease, with limited radiographic reported information. We assessed the imaging patterns of primary and metastatic…”
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A novel community driven software for functional enrichment analysis of extracellular vesicles data by Pathan, Mohashin, Keerthikumar, Shivakumar, Chisanga, David, Alessandro, Riccardo, Ang, Ching-Seng, Askenase, Philip, Batagov, Arsen O., Benito-Martin, Alberto, Camussi, Giovanni, Clayton, Aled, Collino, Federica, Di Vizio, Dolores, Falcon-Perez, Juan Manuel, Fonseca, Pedro, Fonseka, Pamali, Fontana, Simona, Gho, Yong Song, Hendrix, An, Hoen, Esther Nolte-'t, Iraci, Nunzio, Kastaniegaard, Kenneth, Kislinger, Thomas, Kowal, Joanna, Kurochkin, Igor V., Leonardi, Tommaso, Liang, Yaxuan, Llorente, Alicia, Lunavat, Taral R., Maji, Sayantan, Monteleone, Francesca, Øverbye, Anders, Panaretakis, Theocharis, Patel, Tushar, Peinado, Héctor, Pluchino, Stefano, Principe, Simona, Ronquist, Goran, Royo, Felix, Sahoo, Susmita, Spinelli, Cristiana, Stensballe, Allan, Théry, Clotilde, van Herwijnen, Martijn J.C., Wauben, Marca, Welton, Joanne L., Zhao, Kening, Mathivanan, Suresh

“…Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific…”
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