Search Results - "Anett Schallmey"

Expanding the Halohydrin Dehalogenase Enzyme Family: Identification of Novel Enzymes by Database Mining by Schallmey, Marcus, Koopmeiners, Julia, Wells, Elizabeth, Wardenga, Rainer, Schallmey, Anett

“…Halohydrin dehalogenases are very rare enzymes that are naturally involved in the mineralization of halogenated xenobiotics. Due to their catalytic potential…”
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Crystal Contact Engineering for Enhanced Cross-Linking Efficiency of HheG Crystals by Marcel Staar, Sophie Staar, Anett Schallmey

“…The generation of cross-linked enzyme crystals is a very attractive method for immobilization of enzymes displaying high crystalizability. However, the…”
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Selective steroid oxyfunctionalisation by CYP154C5, a bacterial cytochrome P450 by Bracco, Paula, Janssen, Dick B, Schallmey, Anett

“…Cytochrome P450 monooxygenases--able to regio- and stereoselectively hydroxylate non-activated carbon atoms--are important enzymes for the synthesis of…”
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Position 123 of halohydrin dehalogenase HheG plays an important role in stability, activity, and enantioselectivity by Solarczek, Jennifer, Klünemann, Thomas, Brandt, Felix, Schrepfer, Patrick, Wolter, Mario, Jacob, Christoph R., Blankenfeldt, Wulf, Schallmey, Anett

“…HheG from Ilumatobacter coccineus is a halohydrin dehalogenase with synthetically useful activity in the ring opening of cyclic epoxides with various small…”
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Two-Phase Biocatalysis in Microfluidic Droplets by Xiang, Lanting, Kaspar, Felix, Schallmey, Anett, Constantinou, Iordania

“…This Perspective discusses the literature related to two-phase biocatalysis in microfluidic droplets. Enzymes used as catalysts in biocatalysis are generally…”
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The Depth-Dependent Mechanical Behavior of Anisotropic Native and Cross-Linked HheG Enzyme Crystals by Kubiak, Marta, Staar, Marcel, Kampen, Ingo, Schallmey, Anett, Schilde, Carsten

“…Enzymes are able to catalyze various specific reactions under mild conditions and can, therefore, be applied in industrial processes. To ensure process…”
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Two (Chemo)-Enzymatic Cascades for the Production of Opposite Enantiomers of Chiral Azidoalcohols by Elia Calderini, Philipp Süss, Frank Hollmann, Rainer Wardenga, Anett Schallmey

“…Multi-step cascade reactions have gained increasing attention in the biocatalysis field in recent years. In particular, multi-enzymatic cascades can achieve…”
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Bienzymatic Cascade for the Synthesis of an Optically Active O-benzoyl Cyanohydrin by Laura Leemans, Luuk van Langen, Frank Hollmann, Anett Schallmey

“…A concurrent bienzymatic cascade for the synthesis of optically pure (S)-4-methoxymandelonitrile benzoate ((S)-3) starting from 4-anisaldehyde (1) has been…”
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Enzyme-substrate complex structures of CYP154C5 shed light on its mode of highly selective steroid hydroxylation by Herzog, Konrad, Bracco, Paula, Onoda, Akira, Hayashi, Takashi, Hoffmann, Kurt, Schallmey, Anett

“…CYP154C5 from Nocardia farcinica is a bacterial cytochrome P450 monooxygenase active on steroid molecules. The enzyme has recently been shown to exhibit…”
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Characterization of cytochrome P450 monooxygenase CYP154H1 from the thermophilic soil bacterium Thermobifida fusca by Schallmey, Anett, den Besten, Gijs, Teune, Ite G. P, Kembaren, Roga F, Janssen, Dick B

“…Cytochrome P450 monooxygenases are valuable biocatalysts due to their ability to hydroxylate unactivated carbon atoms using molecular oxygen. We have cloned…”
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Multi-Catalytic Route for the Synthesis of (S)-Tembamide by Laura Leemans, Marc D. Walter, Frank Hollmann, Anett Schallmey, Luuk M. van Langen

“…Enantiopure β-amino alcohols constitute one of the most significant building blocks for the synthesis of active pharmaceutical ingredients. Despite the…”
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Enzymatische Ligninverwertung durch bakterielle β-Etherasen by Schallmey, Anett

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Recent advances on halohydrin dehalogenases—from enzyme identification to novel biocatalytic applications by Schallmey, Anett, Schallmey, Marcus

“…Halohydrin dehalogenases are industrially relevant enzymes that catalyze the reversible dehalogenation of vicinal haloalcohols with formation of the…”
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Performance of cross‐linked enzyme crystals of engineered halohydrin dehalogenase HheG in different chemical reactor systems by Staar, Marcel, Schallmey, Anett

“…Halohydrin dehalogenase HheG is an industrially interesting biocatalyst for the preparation of different β‐substituted alcohols starting from bulky internal…”
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Chemo-enzymatic synthesis of natural products and their analogs by Kaspar, Felix, Schallmey, Anett

“…Enzymes continue to gain recognition as valuable tools in synthetic chemistry as they enable transformations, which elude conventional organochemical…”
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UV-Spectroscopic Detection of (Pyro-)Phosphate with the PUB Module by Eilert, Lea, Schallmey, Anett, Kaspar, Felix

“…Despite the prevalence of ortho- and pyrophosphate in biochemistry, operationally simple and versatile high-throughput methodologies for their quantification…”
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Whole-cell cascade for the preparation of enantiopure β-O-4 aryl ether compounds with glutathione recycling by Husarcikova, Jana, Schallmey, Anett

“…•A whole-cell cascade combining β-etherases and glutathione lyase was established.•This enabled efficient β-O-4 aryl ether cleavage with intracellular…”
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G‐type Halohydrin Dehalogenases Catalyze Ring Opening Reactions of Cyclic Epoxides with Diverse Anionic Nucleophiles by Solarczek, Jennifer, Kaspar, Felix, Bauer, Pia, Schallmey, Anett

“…Halohydrin dehalogenases are promiscuous biocatalysts, which enable asymmetric ring opening reactions of epoxides with various anionic nucleophiles. However,…”
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Biocatalytically Active and Stable Cross‐Linked Enzyme Crystals of Halohydrin Dehalogenase HheG by Protein Engineering by Staar, Marcel, Henke, Steffi, Blankenfeldt, Wulf, Schallmey, Anett

“…A major drawback for practical application of halohydrin dehalogenase HheG in biocatalysis is its rather low thermal stability and low organic solvent…”
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Biochemical and biocatalytic characterization of 17 novel halohydrin dehalogenases by Koopmeiners, Julia, Halmschlag, Birthe, Schallmey, Marcus, Schallmey, Anett

“…Halohydrin dehalogenases are rare but catalytically remarkable enzymes since they are able to form novel C–C, C–O, C–N, or C–S bonds. Very recently, a…”
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