Search Results - "Andronati, Sergei A"

Design, Virtual Screening, and Synthesis of Antagonists of αIIbβ3 as Antiplatelet Agents by Polishchuk, Pavel G., Samoylenko, Georgiy V., Khristova, Tetiana M., Krysko, Olga L., Kabanova, Tatyana A., Kabanov, Vladimir M., Kornylov, Alexander Yu, Klimchuk, Olga, Langer, Thierry, Andronati, Sergei A., Kuz’min, Victor E., Krysko, Andrei A., Varnek, Alexandre

“…This article describes design, virtual screening, synthesis, and biological tests of novel αIIbβ3 antagonists, which inhibit platelet aggregation. Two types of…”
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Synthesis, biological evaluation and molecular docking studies of 2-piperazin-1-yl-quinazolines as platelet aggregation inhibitors and ligands of integrin αIIbβ3 by Krysko, Andrei A., Kornylov, Alexander Yu, Polishchuk, Pavel G., Samoylenko, Georgiy V., Krysko, Olga L., Kabanova, Tatyana A., Kravtsov, Victor Ch, Kabanov, Vladimir M., Wicher, Barbara, Andronati, Sergei A.

“…This work reports the synthesis and biological activity of 2-piperazin-1-yl-quinazolines. Molecular docking of ligand–αIIbβ3 complexes showed the key…”
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Synthesis and crystal structures of 7-bromo-5-(2′-chloro)phenyl-3-hydroxy-1-methyl-1,2-dihydro-3H-1,4-benzodiazepin-2-one and 7-bromo-5-(2′-chloro)phenyl-1-hexyl-1,2,4,5-tetrahydro-3H-1,4-benzodiazepin-2,3-dione by Kravtsov, Victor Ch, Fonari, Marina S., Gdaniec, Мaria, Pavlovsky, Victor I., Andronati, Sergei A., Semenishyna, Ekaterina A.

“…► Synthesis and structural study of benzodiazepin-2-one derivatives. ► Influence of substituent in position 1 on heterocycle conformation and distortion. ►…”
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Derivatives of tetrahydroisoquinoline: synthesis and initial evaluation of novel non-peptide antagonists of the alpha(IIb)beta(3)-integrin by Krysko, Andrei A, Krysko, Olga L, Kabanova, Tatyana A, Andronati, Sergei A, Kabanov, Vladimir M

“…The novel RGDF mimetics were synthesized with the use of 4-(1,2,3,4-tetrahydroisoquinoline-7-yl)amino-4-oxobutyric or…”
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RGD mimetics containing phthalimidine fragment as novel ligands of fibrinogen receptor by Krysko, Andrei A., Samoylenko, Georgiy V., Polishchuk, Pavel G., Andronati, Sergei A., Kabanova, Tatyana A., Khristova, Tetiana M., Kuz’min, Victor E., Kabanov, Vladimir M., Krysko, Olga L., Varnek, Alexandre A., Grygorash, Ruslan Ya

“…The novel RGD mimetics with phthalimidine central fragment were synthesized with the use of 4-piperidine-4-yl-butyric, 4-piperidine-4-yl-benzoic,…”
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Derivatives of tetrahydroisoquinoline: Synthesis and initial evaluation of novel non-peptide antagonists of the αIIbβ3-integrin by Krysko, Andrei A., Krysko, Olga L., Kabanova, Tatyana A., Andronati, Sergei A., Kabanov, Vladimir M.

“…The synthesis of the novel fibrinogen receptor antagonists. The novel RGDF mimetics were synthesized with the use of…”
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Derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids as novel fibrinogen receptor antagonists by Malovichko, Olga L., Petrus, Anna S., Krysko, Andrei A., Kabanova, Tatyana A., Andronati, Sergei A., Karaseva, Tamara L., Kiriyak, Anna V.

“…The synthesis of the novel fibrinogen receptor antagonists 9a– 9h is reported. The novel fibrinogen receptor antagonists containing fragments of…”
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Novel fibrinogen receptor antagonists. RGDF mimetics, derivatives of 4-(isoindoline-5-yl)amino-4-oxobutyric acid by Krysko, Andrei A., Chugunov, Boris M., Malovichko, Olga L., Andronati, Sergei A., Kabanova, Tatyana A., Karaseva, Tamara L., Kiriyak, Anna V.

“…The novel RGDF mimetics 9a and 9b were synthesized with the use of 4-(isoindoline-5-yl)amino-4-oxobutyric acid as a surrogate of Arg-Gly motif. The synthesized…”
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Derivatives of 1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid as novel fibrinogen receptor antagonists by Malovichko, Olga L, Krysko, Andrei A, Kabanova, Tatyana A, Andronati, Sergei A, Grishkovets, Vladimir I, Kachala, Vadim V, Panov, Denis A

“…It has been proposed a novel method for obtaining of 1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid as Arg-mimetic within the framework of search for novel…”
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Novel fibrinogen receptor antagonists--RGDF mimetics, 4-(1,2,3,4-tetrahydro-isoquinoline-7-yl)amino-4-oxo-butyric acid derivatives by Krysko, Andrei A, Malovichko, Olga L, Andronati, Sergei A, Kabanova, Tatyana A, Karaseva, Tamara L, Petrus, Anna S

“…Two novel RGDF mimetics were synthesized with the use of 4-(1,2,3,4-tetrahydro-isoquinoline-7-yl)amino-4-oxo-butyric acid as a new surrogate of Arg-Gly motif…”
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Synthesis and antiaggregatory activity of RGD-peptidomimetics based on 4-oxo-4-(piperazine-1-yl)butyric acid as Arg-mimetic by Andronati, Sergei A, Krysko, Andrei A, Kabanov, Vladimir M, Kabanova, Tatyana A, Karaseva, Tamara L, Chugunov, Boris M, Meshkova, Svetlana B, Topilova, Zoya M

“…A scheme of synthesis of previously obtained RGDF-peptidomimetic-4-oxo-4-(piperazine-1-yl)butyrylglycyl-D,L-beta-phenyl-beta-alanine (I), was simplified. The…”
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1,3-Phosphorotropic migration in the C super(3)NC super(5) triad of 1,4-benzodiazepines accompanied by isomerization of Ph sub(2)POC super(3)NC super(5) to Ph sub(2)P(O)C super(5)NC super(3) by Gololobov, Yuri G, Krasnova, Irina Yu, Barabanov, Sergei V, Khrustalev, Viktor N, Andronati, Sergei A, Pavlovsky, Viktor I

“…It is demonstrated that phosphorotropic migration occurs in the C super(3)NC super(5) triad of 1,4-benzodiazepines, which is accompanied by the isomerization…”
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1,3-Phosphorotropic migration in the C3NC5 triad of 1,4-benzodiazepines accompanied by isomerization of Ph2POC3NC5 to Ph2P(O)C5NC3 by Gololobov, Yuri G., Krasnova, Irina Yu, Barabanov, Sergei V., Khrustalev, Viktor N., Andronati, Sergei A., Pavlovsky, Viktor I.

“…It is demonstrated that phosphorotropic migration occurs in the C3NC5 triad of 1,4-benzodiazepines, which is accompanied by the isomerization of Ph2POC3 to…”
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Design, Virtual Screening, and Synthesis of Antagonists of α IIb β 3 as Antiplatelet Agents by Polishchuk, Pavel G., Samoylenko, Georgiy V., Khristova, Tetiana M., Krysko, Olga L., Kabanova, Tatyana A., Kabanov, Vladimir M., Kornylov, Alexander Yu, Klimchuk, Olga, Langer, Thierry, Andronati, Sergei A., Kuz’min, Victor E., Krysko, Andrei A., Varnek, Alexandre

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Synthesis, biological evaluation, X-ray molecular structure and molecular docking studies of RGD mimetics containing 6-amino-2,3-dihydroisoindolin-1-one fragment as ligands of integrin αIIbβ3 by Krysko, Andrei A., Samoylenko, Georgiy V., Polishchuk, Pavel G., Fonari, Marina S., Kravtsov, Victor Ch, Andronati, Sergei A., Kabanova, Tatyana A., Lipkowski, Janusz, Khristova, Tetiana M., Kuz’min, Victor E., Kabanov, Vladimir M., Krysko, Olga L., Varnek, Alexandre A.

“…A series of novel RGD mimetics containing phthalimidine fragment was designed and synthesized. Their antiaggregative activity determined by Born’s method was…”
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Synthesis, biological evaluation, X-ray molecular structure and molecular docking studies of RGD mimetics containing 6-amino-2,3-dihydroisoindolin-1-one fragment as ligands of integrin αIIbβ by Krysko, Andrei A, Samoylenko, Georgiy V, Polishchuk, Pavel G, Fonari, Marina S, Kravtsov, Victor Ch, Andronati, Sergei A, Kabanova, Tatyana A, Lipkowski, Janusz, Khristova, Tetiana M, Kuz’min, Victor E, Kabanov, Vladimir M, Krysko, Olga L, Varnek, Alexandre A

“…A series of novel RGD mimetics containing phthalimidine fragment was designed and synthesized. Their antiaggregative activity determined by Born’s method was…”
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Synthesis and crystal structures of 7-bromo-5-(2a2-chloro)phenyl-3-hydroxy-1-methyl-1,2-dihydro-3H-1,4 -benzodiazepin-2-one and 7-bromo-5-(2a2-chloro)phenyl-1-hexyl-1,2,4,5-tetrahydro-3H-1,4-ben zodiazepin-2,3-dione by Kravtsov, Victor Ch, Fonari, Marina S, Gdaniec, Taria, Pavlovsky, Victor I, Andronati, Sergei A, Semenishyna, Ekaterina A

“…Treatment of 7-bromo-5-(2a2-chloro)phenyl-3-hydroxy-1,2-dihydro-3H-1,4-benzodia zepin-2-one (1) with methyl or hexyl tosylate resulted in…”
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Derivatives of tetrahydroisoquinoline: Synthesis and initial evaluation of novel non-peptide antagonists of the a sub(IIb)b sub(3)-integrin by Krysko, Andrei A, Krysko, Olga L, Kabanova, Tatyana A, Andronati, Sergei A, Kabanov, Vladimir M

“…The novel RGDF mimetics were synthesized with the use of 4-(1,2,3,4-tetrahydroisoquinoline-7-yl)amino-4-oxobutyric or…”
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TRH mimetics: Differentiation of antiamnesic potency from antidepressant effect by Mazurov, Anatoly A., Andronati, Sergei A., Korotenko, Tamara I., Sokolenko, Nikolai I., Dyadenko, Alexei I., Shapiro, Yury E., Gorbatyuk, Vitalii Ya, Voronina, Tatyana A.

“…For the purpose of rational modification of the TRH molecule, we were pursuing an approach that consists of two steps: (1) ‘obligatory’ replacement of…”
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Design of a novel cognitive enhancer (8S, 10aS)-8-carbamoyl-1,2,3,6,7,8,9,10a-octahydro-5H,10H-pyrrolo[1,2-a][1,4]diazocin-5,10-dione by Mazurov, Anatoly A., Andronati, Sergei A., Korotenko, Tamara I., Sokolenko, Nikolai I., Dyadenko, Alexei I., Shapiro, Yuri E., Gorbatyuk, Vitalii Ya, Voronina, Tatyana A.

“…A new cognitive enhancer (8S, 10aS)-8-carbamoyl-1,2,3,6,7,8,9,10a-octahydro-5H,10H-pyrrolo[1,2-a][1,4]diazocin-5,10-dione ( 3) has been designed based on the…”
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