Search Results - "Andries, Julie"
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The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
Published in Nature communications (14-10-2022)“…Binding to the neonatal Fc receptor (FcRn) extends serum half-life of IgG, and antagonizing this interaction is a promising therapeutic approach in…”
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The pros and confs of IL-18 activation
Published in Immunity (Cambridge, Mass.) (09-07-2024)“…Interleukin-1 (IL-1) family cytokines are key immunological regulators that achieve their signaling prowess after post-translational proteolytic processing. In…”
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Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity
Published in The Journal of biological chemistry (01-05-2022)“…Human Interleukin-18 (IL-18) is an omnipresent proinflammatory cytokine of the IL-1 family with central roles in autoimmune and inflammatory diseases and…”
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